PPIH | ENSG00000171960 | NCBI 10465

Details for: PPIH

Gene ID: 10465

Symbol: PPIH

Ensembl ID: ENSG00000171960

Description: peptidylprolyl isomerase H

Associated with

Disease
(R-HSA-1643685)
Infectious disease
(R-HSA-5663205)
Metabolism of rna
(R-HSA-8953854)
Mrna splicing
(R-HSA-72172)
Mrna splicing - major pathway
(R-HSA-72163)
Processing of capped intron-containing pre-mrna
(R-HSA-72203)
Sars-cov-1 activates/modulates innate immune responses
(R-HSA-9692916)
Sars-cov-1 infection
(R-HSA-9678108)
Sars-cov-1-host interactions
(R-HSA-9692914)
Sars-cov infections
(R-HSA-9679506)
Viral infection pathways
(R-HSA-9824446)
Cyclosporin a binding
(GO:0016018)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Intracellular membrane-bounded organelle
(GO:0043231)
Mrna splicing, via spliceosome
(GO:0000398)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Peptidyl-prolyl cis-trans isomerase activity
(GO:0003755)
Positive regulation of viral genome replication
(GO:0045070)
Protein-containing complex assembly
(GO:0065003)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein peptidyl-prolyl isomerization
(GO:0000413)
Ribonucleoprotein complex binding
(GO:0043021)
Spliceosomal complex
(GO:0005681)
U4/u6 snrnp
(GO:0071001)
U4/u6 x u5 tri-snrnp complex
(GO:0046540)

Other Information

Proteins

Peptidyl-prolyl cis-trans isomerase H

Genular Protein ID: 1773919074

Symbol: PPIH_HUMAN

Name: Peptidyl-prolyl cis-trans isomerase H

UniProtKB Accession Codes:

O43447 A6NNE7

Database IDs:

Citations:

PubMed ID: 9404889

Title: A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs.

PubMed ID: 9404889

PubMed ID: 9570313

Title: The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins.

PubMed ID: 9570313

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11823439

Title: A cyclophilin functions in pre-mRNA splicing.

PubMed ID: 11823439

DOI: 10.1093/emboj/21.3.470

PubMed ID: 16723661

Title: The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.

PubMed ID: 16723661

DOI: 10.1261/rna.55406

PubMed ID: 20676357

Title: Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.

PubMed ID: 20676357

DOI: 10.1371/journal.pbio.1000439

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 10713041

Title: Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin.

PubMed ID: 10713041

DOI: 10.1074/jbc.275.11.7439

PubMed ID: 12875835

Title: Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide.

PubMed ID: 12875835

DOI: 10.1016/s0022-2836(03)00684-3

Sequence Information:

Length: 177
Mass: 19208
Checksum: 566BCE6361E0F339
Sequence:

MAVANSSPVN PVVFFDVSIG GQEVGRMKIE LFADVVPKTA ENFRQFCTGE FRKDGVPIGY 
KGSTFHRVIK DFMIQGGDFV NGDGTGVASI YRGPFADENF KLRHSAPGLL SMANSGPSTN 
GCQFFITCSK CDWLDGKHVV FGKIIDGLLV MRKIENVPTG PNNKPKLPVV ISQCGEM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: PPIH

Associated with

Other Information

A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. PubMed ID: 9404889

The 20kD protein of human [U4/U6.U5] tri-snRNPs is a novel cyclophilin that forms a complex with the U4/U6-specific 60kD and 90kD proteins. PubMed ID: 9570313

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A cyclophilin functions in pre-mRNA splicing. PubMed ID: 11823439

The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP. PubMed ID: 16723661

Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases. PubMed ID: 20676357

Initial characterization of the human central proteome. PubMed ID: 21269460

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Crystal structure of the human U4/U6 small nuclear ribonucleoprotein particle-specific SnuCyp-20, a nuclear cyclophilin. PubMed ID: 10713041

Crystal structure of a complex between human spliceosomal cyclophilin H and a U4/U6 snRNP-60K peptide. PubMed ID: 12875835