Details for: FST

Gene ID: 10468

Symbol: FST

Ensembl ID: ENSG00000134363

Description: follistatin

Associated with

Other Information

Genular Protein ID: 505704772

Symbol: FST_HUMAN

Name: N/A

UniProtKB Accession Codes:

P19883 B5BU94 Q9BTH0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 6 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 4 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 3380788

Title: Primary structure of the human follistatin precursor and its genomic organization.

PubMed ID: 3380788

DOI: 10.1073/pnas.85.12.4218

PubMed ID: 19054851

Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.

PubMed ID: 19054851

DOI: 10.1038/nmeth.1273

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 15472207

Title: Differential distribution of follistatin isoforms: application of a new FS315-specific immunoassay.

PubMed ID: 15472207

DOI: 10.1210/jc.2004-0162

PubMed ID: 31215115

Title: Mutations in GDF11 and the extracellular antagonist, Follistatin, as a likely cause of Mendelian forms of orofacial clefting in humans.

PubMed ID: 31215115

DOI: 10.1002/humu.23793

PubMed ID: 16198295

Title: The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding.

PubMed ID: 16198295

DOI: 10.1016/j.devcel.2005.09.008

PubMed ID: 17409095

Title: Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions.

PubMed ID: 17409095

DOI: 10.1074/jbc.m700737200

PubMed ID: 19644449

Title: The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding.

PubMed ID: 19644449

DOI: 10.1038/emboj.2009.205

PubMed ID: 28257634

Title: Structural basis for potency differences between GDF8 and GDF11.

PubMed ID: 28257634

DOI: 10.1186/s12915-017-0350-1

Sequence Information:

  • Length: 344
  • Mass: 38007
  • Checksum: D9BB45055D84AC90
  • Sequence:
    • MVRARHQPGG LCLLLLLLCQ FMEDRSAQAG NCWLRQAKNG RCQVLYKTEL SKEECCSTGR 
LSTSWTEEDV NDNTLFKWMI FNGGAPNCIP CKETCENVDC GPGKKCRMNK KNKPRCVCAP 
DCSNITWKGP VCGLDGKTYR NECALLKARC KEQPELEVQY QGRCKKTCRD VFCPGSSTCV 
VDQTNNAYCV TCNRICPEPA SSEQYLCGND GVTYSSACHL RKATCLLGRS IGLAYEGKCI 
KAKSCEDIQC TGGKKCLWDF KVGRGRCSLC DELCPDSKSD EPVCASDNAT YASECAMKEA 
ACSSGVLLEV KHSGSCNSIS EDTEEEEEDE DQDYSFPISS ILEW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.