ZBTB18 | ENSG00000179456 | NCBI 10472

Details for: ZBTB18

Gene ID: 10472

Symbol: ZBTB18

Ensembl ID: ENSG00000179456

Description: zinc finger and BTB domain containing 18

Associated with

Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription repressor activity, rna polymerase ii-specific
(GO:0001227)
Dna binding
(GO:0003677)
Heterochromatin
(GO:0000792)
Metal ion binding
(GO:0046872)
Negative regulation of dna-templated transcription
(GO:0045892)
Negative regulation of transcription by rna polymerase ii
(GO:0000122)
Nuclear speck
(GO:0016607)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)
Skeletal muscle tissue development
(GO:0007519)

Other Information

Proteins

Zinc finger and BTB domain-containing protein 18

Genular Protein ID: 430964142

Symbol: ZBT18_HUMAN

Name: Zinc finger and BTB domain-containing protein 18

UniProtKB Accession Codes:

Q99592 A8K5U3 Q13397 Q5VU40 Q8N463 Q9UD99

Database IDs:

Citations:

PubMed ID: 7633419

Title: Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.

PubMed ID: 7633419

DOI: 10.1093/hmg/4.4.685

PubMed ID: 9756912

Title: RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression.

PubMed ID: 9756912

DOI: 10.1074/jbc.273.41.26698

PubMed ID: 10721697

Title: Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin.

PubMed ID: 10721697

DOI: 10.1016/s0378-1119(99)00477-1

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8358434

Title: 3,400 new expressed sequence tags identify diversity of transcripts in human brain.

PubMed ID: 8358434

DOI: 10.1038/ng0793-256

PubMed ID: 11350943

Title: Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.

PubMed ID: 11350943

DOI: 10.1093/emboj/20.10.2536

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 24193349

Title: A de novo non-sense mutation in ZBTB18 in a patient with features of the 1q43q44 microdeletion syndrome.

PubMed ID: 24193349

DOI: 10.1038/ejhg.2013.249

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 26740508

Title: Identification of novel genetic causes of Rett syndrome-like phenotypes.

PubMed ID: 26740508

DOI: 10.1136/jmedgenet-2015-103568

Sequence Information:

Length: 522
Mass: 58354
Checksum: DE024B66E02DCE75
Sequence:

MEFPDHSRHL LQCLSEQRHQ GFLCDCTVLV GDAQFRAHRA VLASCSMYFH LFYKDQLDKR 
DIVHLNSDIV TAPAFALLLE FMYEGKLQFK DLPIEDVLAA ASYLHMYDIV KVCKKKLKEK 
ATTEADSTKK EEDASSCSDK VESLSDGSSH IAGDLPSDED EGEDEKLNIL PSKRDLAAEP 
GNMWMRLPSD SAGIPQAGGE AEPHATAAGK TVASPCSSTE SLSQRSVTSV RDSADVDCVL 
DLSVKSSLSG VENLNSSYFS SQDVLRSNLV QVKVEKEASC DESDVGTNDY DMEHSTVKES 
VSTNNRVQYE PAHLAPLRED SVLRELDRED KASDDEMMTP ESERVQVEGG MESSLLPYVS 
NILSPAGQIF MCPLCNKVFP SPHILQIHLS THFREQDGIR SKPAADVNVP TCSLCGKTFS 
CMYTLKRHER THSGEKPYTC TQCGKSFQYS HNLSRHAVVH TREKPHACKW CERRFTQSGD 
LYRHIRKFHC ELVNSLSVKS EALSLPTVRD WTLEDSSQEL WK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ZBTB18

Associated with

Other Information

Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain. PubMed ID: 7633419

RP58 associates with condensed chromatin and mediates a sequence-specific transcriptional repression. PubMed ID: 9756912

Structural analysis of the gene encoding RP58, a sequence-specific transrepressor associated with heterochromatin. PubMed ID: 10721697

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

3,400 new expressed sequence tags identify diversity of transcripts in human brain. PubMed ID: 8358434

Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. PubMed ID: 11350943

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

A de novo non-sense mutation in ZBTB18 in a patient with features of the 1q43q44 microdeletion syndrome. PubMed ID: 24193349

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

Identification of novel genetic causes of Rett syndrome-like phenotypes. PubMed ID: 26740508