TRIM38 | ENSG00000112343 | NCBI 10475

Details for: TRIM38

Gene ID: 10475

Symbol: TRIM38

Ensembl ID: ENSG00000112343

Description: tripartite motif containing 38

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Interferon gamma signaling
(R-HSA-877300)
Interferon signaling
(R-HSA-913531)
Cellular_component
(GO:0005575)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Innate immune response
(GO:0045087)
Negative regulation of defense response to virus
(GO:0050687)
Nucleoplasm
(GO:0005654)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of nf-kappab transcription factor activity
(GO:0051092)
Positive regulation of viral entry into host cell
(GO:0046598)
Positive regulation of viral genome replication
(GO:0045070)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Protein k48-linked ubiquitination
(GO:0070936)
Protein kinase binding
(GO:0019901)
Protein polyubiquitination
(GO:0000209)
Protein sumoylation
(GO:0016925)
Regulation of interferon-beta production
(GO:0032648)
Regulation of protein localization
(GO:0032880)
Regulation of viral entry into host cell
(GO:0046596)
Transcription coactivator activity
(GO:0003713)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

RING finger protein 15

Genular Protein ID: 297090993

Symbol: TRI38_HUMAN

Name: RING finger protein 15

UniProtKB Accession Codes:

O00635 B2R862

Database IDs:

Citations:

PubMed ID: 9149941

Title: A 1.1-Mb transcript map of the hereditary hemochromatosis locus.

PubMed ID: 9149941

DOI: 10.1101/gr.7.5.441

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23056470

Title: TRIM38 negatively regulates TLR3-mediated IFN-beta signaling by targeting TRIF for degradation.

PubMed ID: 23056470

DOI: 10.1371/journal.pone.0046825

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24434549

Title: TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.

PubMed ID: 24434549

DOI: 10.1073/pnas.1318227111

Sequence Information:

Length: 465
Mass: 53416
Checksum: 30A884051A2DA058
Sequence:

MASTTSTKKM MEEATCSICL SLMTNPVSIN CGHSYCHLCI TDFFKNPSQK QLRQETFCCP 
QCRAPFHMDS LRPNKQLGSL IEALKETDQE MSCEEHGEQF HLFCEDEGQL ICWRCERAPQ 
HKGHTTALVE DVCQGYKEKL QKAVTKLKQL EDRCTEQKLS TAMRITKWKE KVQIQRQKIR 
SDFKNLQCFL HEEEKSYLWR LEKEEQQTLS RLRDYEAGLG LKSNELKSHI LELEEKCQGS 
AQKLLQNVND TLSRSWAVKL ETSEAVSLEL HTMCNVSKLY FDVKKMLRSH QVSVTLDPDT 
AHHELILSED RRQVTRGYTQ ENQDTSSRRF TAFPCVLGCE GFTSGRRYFE VDVGEGTGWD 
LGVCMENVQR GTGMKQEPQS GFWTLRLCKK KGYVALTSPP TSLHLHEQPL LVGIFLDYEA 
GVVSFYNGNT GCHIFTFPKA SFSDTLRPYF QVYQYSPLFL PPPGD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TRIM38

Associated with

Other Information

A 1.1-Mb transcript map of the hereditary hemochromatosis locus. PubMed ID: 9149941

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Initial characterization of the human central proteome. PubMed ID: 21269460

TRIM38 negatively regulates TLR3-mediated IFN-beta signaling by targeting TRIF for degradation. PubMed ID: 23056470

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3. PubMed ID: 24434549