Details for: SLC9A6
Associated with
Other Information
Genular Protein ID: 2871928190
Symbol: SL9A6_HUMAN
Name: Sodium/hydrogen exchanger 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9507001
Title: Identification of a mitochondrial Na+/H+ exchanger.
PubMed ID: 9507001
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9039502
Title: Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.
PubMed ID: 9039502
PubMed ID: 11641397
Title: NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell.
PubMed ID: 11641397
PubMed ID: 11940519
Title: Human Na(+)/H(+) exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria.
PubMed ID: 11940519
PubMed ID: 15522866
Title: Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi Compartments and are involved in organelle pH regulation.
PubMed ID: 15522866
PubMed ID: 17370265
Title: Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry.
PubMed ID: 17370265
PubMed ID: 18057008
Title: Cell surface levels of organellar Na+/H+ exchanger isoform 6 are regulated by interaction with RACK1.
PubMed ID: 18057008
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 20130086
Title: The Na+/H+ exchanger NHE6 in the endosomal recycling system is involved in the development of apical bile canalicular surface domains in HepG2 cells.
PubMed ID: 20130086
PubMed ID: 18342287
Title: SLC9A6 mutations cause X-linked mental retardation, microcephaly, epilepsy, and ataxia, a phenotype mimicking Angelman syndrome.
PubMed ID: 18342287
PubMed ID: 24123876
Title: Identification of pathogenic gene variants in small families with intellectually disabled siblings by exome sequencing.
PubMed ID: 24123876
PubMed ID: 28635961
Title: Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance.
PubMed ID: 28635961
DOI: 10.1038/ncomms15884
PubMed ID: 25044251
Title: Genetic and phenotypic diversity of NHE6 mutations in Christianson syndrome.
PubMed ID: 25044251
DOI: 10.1002/ana.24225
PubMed ID: 30296617
Title: A potential gain-of-function variant of SLC9A6 leads to endosomal alkalinization and neuronal atrophy associated with Christianson Syndrome.
PubMed ID: 30296617
PubMed ID: 31676550
Title: Functional Assessment In Vivo of the Mouse Homolog of the Human Ala-9-Ser NHE6 Variant.
PubMed ID: 31676550
PubMed ID: 32277048
Title: Assorted dysfunctions of endosomal alkali cation/proton exchanger SLC9A6 variants linked to Christianson syndrome.
PubMed ID: 32277048
Sequence Information:
- Length: 701
- Mass: 77917
- Checksum: A2BE0E4EF07A62EC
- Sequence:
MARRGWRRAP LRRGVGSSPR ARRLMRPLWL LLAVGVFDWA GASDGGGGEA RAMDEEIVSE KQAEESHRQD SANLLIFILL LTLTILTIWL FKHRRARFLH ETGLAMIYGL LVGLVLRYGI HVPSDVNNVT LSCEVQSSPT TLLVNVSGKF YEYMLKGEIS SHELNNVQDN EMLRKVTFDP EVFFNILLPP IIFYAGYSLK RRHFFRNLGS ILAYAFLGTA ISCFVIGSIM YGCVTLMKVT GQLAGDFYFT DCLLFGAIVS ATDPVTVLAI FHELQVDVEL YALLFGESVL NDAVAIVLSS SIVAYQPAGD NSHTFDVTAM FKSIGIFLGI FSGSFAMGAA TGVVTALVTK FTKLREFQLL ETGLFFLMSW STFLLAEAWG FTGVVAVLFC GITQAHYTYN NLSTESQHRT KQLFELLNFL AENFIFSYMG LTLFTFQNHV FNPTFVVGAF VAIFLGRAAN IYPLSLLLNL GRRSKIGSNF QHMMMFAGLR GAMAFALAIR DTATYARQMM FSTTLLIVFF TVWVFGGGTT AMLSCLHIRV GVDSDQEHLG VPENERRTTK AESAWLFRMW YNFDHNYLKP LLTHSGPPLT TTLPACCGPI ARCLTSPQAY ENQEQLKDDD SDLILNDGDI SLTYGDSTVN TEPATSSAPR RFMGNSSEDA LDRELAFGDH ELVIRGTRLV LPMDDSEPPL NLLDNTRHGP A
Genular Protein ID: 3275843093
Symbol: A0A1B0GV11_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15772651
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 617
- Mass: 68505
- Checksum: 853497A2D6FD9E99
- Sequence:
MDEEIVSEKQ AEESHRQDSA NLLIFILLLT LTILTIWLFK HRRARFLHET GLAMIYGLLV GLVLRYGIHV PSDVNNVTLS CEVQSSPTTL LVTFDPEVFF NILLPPIIFY AGYSLKRRHF FRNLGSILAY AFLGTAISCF VIGSIMYGCV TLMKVTGQLA GDFYFTDCLL FGAIVSATDP VTVLAIFHEL QVDVELYALL FGESVLNDAV AIVLSSSIVA YQPAGDNSHT FDVTAMFKSI GIFLGIFSGS FAMGAATGVV TALVTKFTKL REFQLLETGL FFLMSWSTFL LAEAWGFTGV VAVLFCGITQ AHYTYNNLST ESQHRTKQLF ELLNFLAENF IFSYMGLTLF TFQNHVFNPT FVVGAFVAIF LGRAANIYPL SLLLNLGRRS KIGSNFQHMM MFAGLRGAMA FALAIRDTAT YARQMMFSTT LLIVFFTVWV FGGGTTAMLS CLHIRVGVDS DQEHLGVPEN ERRTTKAESA WLFRMWYNFD HNYLKPLLTH SGPPLTTTLP ACCGPIARCL TSPQAYENQE QLKDDDSDLI LNDGDISLTY GDSTVNTEPA TSSAPRRFMG NSSEDALDRE LAFGDHELVI RGTRLVLPMD DSEPPLNLLD NTRHGPA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.