CEACAM5 | ENSG00000105388 | NCBI 1048

Details for: CEACAM5

Gene ID: 1048

Symbol: CEACAM5

Ensembl ID: ENSG00000105388

Description: CEA cell adhesion molecule 5

Associated with

Cell surface interactions at the vascular wall
(R-HSA-202733)
Hemostasis
(R-HSA-109582)
Metabolism of proteins
(R-HSA-392499)
Post-translational modification: synthesis of gpi-anchored proteins
(R-HSA-163125)
Post-translational protein modification
(R-HSA-597592)
Apical plasma membrane
(GO:0016324)
Apoptotic process
(GO:0006915)
Basolateral plasma membrane
(GO:0016323)
Cell surface
(GO:0009986)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Gpi anchor binding
(GO:0034235)
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
(GO:0007157)
Homophilic cell adhesion via plasma membrane adhesion molecules
(GO:0007156)
Homotypic cell-cell adhesion
(GO:0034109)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Negative regulation of anoikis
(GO:2000811)
Negative regulation of apoptotic process
(GO:0043066)
Negative regulation of myotube differentiation
(GO:0010832)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein homodimerization activity
(GO:0042803)
Side of membrane
(GO:0098552)

Other Information

Proteins

Carcinoembryonic antigen-related cell adhesion molecule 5
Q53G30_HUMAN

Genular Protein ID: 1817482593

Symbol: CEAM5_HUMAN

Name: Carcinoembryonic antigen-related cell adhesion molecule 5

UniProtKB Accession Codes:

P06731 H9KVA7

Database IDs:

Citations:

PubMed ID: 3670312

Title: Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.

PubMed ID: 3670312

DOI: 10.1128/mcb.7.9.3221-3230.1987

PubMed ID: 3220478

Title: Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.

PubMed ID: 3220478

DOI: 10.1016/0888-7543(88)90160-7

PubMed ID: 2342461

Title: Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.

PubMed ID: 2342461

DOI: 10.1128/mcb.10.6.2738-2748.1990

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 3814146

Title: Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.

PubMed ID: 3814146

DOI: 10.1016/0006-291x(87)90304-4

PubMed ID: 3033671

Title: Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.

PubMed ID: 3033671

DOI: 10.1073/pnas.84.9.2960

PubMed ID: 2803308

Title: Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.

PubMed ID: 2803308

DOI: 10.1016/0006-291x(89)91679-3

PubMed ID: 2317824

Title: Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.

PubMed ID: 2317824

PubMed ID: 10436421

Title: Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.

PubMed ID: 10436421

DOI: 10.1159/000030075

PubMed ID: 10910050

Title: Human carcinoembryonic antigen functions as a general inhibitor of anoikis.

PubMed ID: 10910050

PubMed ID: 10864933

Title: Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion.

PubMed ID: 10864933

DOI: 10.1074/jbc.m909242199

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 26483485

Title: Diverse oligomeric states of CEACAM IgV domains.

PubMed ID: 26483485

DOI: 10.1073/pnas.1509511112

PubMed ID: 10854848

Title: Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.

PubMed ID: 10854848

DOI: 10.1016/s0014-5793(00)01612-4

PubMed ID: 18086185

Title: Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.

PubMed ID: 18086185

DOI: 10.1111/j.1365-2958.2007.06054.x

Sequence Information:

Length: 702
Mass: 76796
Checksum: 6299AE26CDDBDB5C
Sequence:

MESPSAPPHR WCIPWQRLLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLVHNLPQ 
HLFGYSWYKG ERVDGNRQII GYVIGTQQAT PGPAYSGREI IYPNASLLIQ NIIQNDTGFY 
TLHVIKSDLV NEEATGQFRV YPELPKPSIS SNNSKPVEDK DAVAFTCEPE TQDATYLWWV 
NNQSLPVSPR LQLSNGNRTL TLFNVTRNDT ASYKCETQNP VSARRSDSVI LNVLYGPDAP 
TISPLNTSYR SGENLNLSCH AASNPPAQYS WFVNGTFQQS TQELFIPNIT VNNSGSYTCQ 
AHNSDTGLNR TTVTTITVYA EPPKPFITSN NSNPVEDEDA VALTCEPEIQ NTTYLWWVNN 
QSLPVSPRLQ LSNDNRTLTL LSVTRNDVGP YECGIQNELS VDHSDPVILN VLYGPDDPTI 
SPSYTYYRPG VNLSLSCHAA SNPPAQYSWL IDGNIQQHTQ ELFISNITEK NSGLYTCQAN 
NSASGHSRTT VKTITVSAEL PKPSISSNNS KPVEDKDAVA FTCEPEAQNT TYLWWVNGQS 
LPVSPRLQLS NGNRTLTLFN VTRNDARAYV CGIQNSVSAN RSDPVTLDVL YGPDTPIISP 
PDSSYLSGAN LNLSCHSASN PSPQYSWRIN GIPQQHTQVL FIAKITPNNN GTYACFVSNL 
ATGRNNSIVK SITVSASGTS PGLSAGATVG IMIGVLVGVA LI

Genular Protein ID: 1008400546

Symbol: Q53G30_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53G30

Database IDs:

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

Length: 702
Mass: 76868
Checksum: 62992426CDDABB5C
Sequence:

MESPSAPPHR WCIPWQRLLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLVHNLPQ 
HLFGYSWYKG ERVDGNRQII GYVIGTQQAT PGPAYSGREI IYPNASLLIQ NIIQNDTGFY 
TLHVIKSDLV NEEATGQFRV YPELPKPSIS SNNSKPVEDK DAVAFTCEPE TQDATYLWWV 
NNQSLPVSPR LQLSNGNRTL TLFNVTRNDT ASYKCETQNP VSARRSDSVI LNVLYGPDAP 
TISPLNTSYR SGENLNLSCH AASNPPAQYS WFVNGTFQQS TQELFIPNIT VNNSGSYTCQ 
AHNSDTGLNR TTVTTITVYA EPPKPFITSN NSNPVEDEDA VALTCEPEIQ NTTYLWWVNN 
QSLPVSPRLQ LSNDNRTLTL LSVTRNDVGP YECGIQNELS VDHSDPVILN VLYGPDDPTI 
SPSYTYYRPG VNLSLSCHAA SNPPAQYSWL IDENIQQHTQ ELFISNITEK NSGLYTCQAN 
NSASGHSRTT VKTITVSAEL PKPSISSNNS KPVEDKDAVA FTCEPEAQNT TYLWWVNGQS 
LPVSPRLQLS NGNRTLTLFN VTRNDARAYV CGIQNSVSAN RSDPVTLDVL YGPDTPIISP 
PDSSYLSGAN LNLSCHSASN PSPQYSWRIN GIPQQHTQVL FIAKITPNNN GTYACFVSNL 
ATGRNNSIVK SITVSASGTS PGLSAGATVG IMIGVLVGVA LI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CEACAM5

Associated with

Other Information

Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen. PubMed ID: 3670312

Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. PubMed ID: 3220478

Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression. PubMed ID: 2342461

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. PubMed ID: 3814146

Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure. PubMed ID: 3033671

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion. PubMed ID: 2803308

Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products. PubMed ID: 2317824

Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat. PubMed ID: 10436421

Human carcinoembryonic antigen functions as a general inhibitor of anoikis. PubMed ID: 10910050

Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion. PubMed ID: 10864933

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. PubMed ID: 16740002

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

Diverse oligomeric states of CEACAM IgV domains. PubMed ID: 26483485

Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. PubMed ID: 10854848

Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. PubMed ID: 18086185

Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. PubMed ID: 8125298

Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. PubMed ID: 9373149