Details for: CEACAM5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: ileal goblet cell (CL1000326)
Fold Change: 21.7728
Cell Significance Index: -14.6100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 7.1196
Cell Significance Index: 322.7100 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.4501
Cell Significance Index: -14.6000 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 4.5785
Cell Significance Index: 49.6200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 3.3303
Cell Significance Index: 388.1200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.5588
Cell Significance Index: 33.7700 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.4594
Cell Significance Index: 1317.7100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.4562
Cell Significance Index: 21.8200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.2711
Cell Significance Index: 125.7400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 1.1001
Cell Significance Index: 125.5800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.9187
Cell Significance Index: 63.5300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8368
Cell Significance Index: 26.8000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7834
Cell Significance Index: 127.4100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.5128
Cell Significance Index: 18.0200 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.4234
Cell Significance Index: 3.5000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.3881
Cell Significance Index: 81.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2949
Cell Significance Index: 32.0800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1801
Cell Significance Index: 34.2700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0986
Cell Significance Index: 2.8400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0790
Cell Significance Index: 49.3500 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.0552
Cell Significance Index: 0.3600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0235
Cell Significance Index: 0.5000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0232
Cell Significance Index: 0.5800 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0222
Cell Significance Index: 12.1500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0129
Cell Significance Index: 0.5600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0019
Cell Significance Index: 0.3400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0004
Cell Significance Index: -0.2900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0005
Cell Significance Index: -0.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0155
Cell Significance Index: -11.7000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0260
Cell Significance Index: -3.2000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0378
Cell Significance Index: -17.1400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0388
Cell Significance Index: -13.9100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0601
Cell Significance Index: -0.8200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0649
Cell Significance Index: -3.9800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0690
Cell Significance Index: -13.8400 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0693
Cell Significance Index: -0.7600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0715
Cell Significance Index: -12.2100 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0749
Cell Significance Index: -1.2600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0809
Cell Significance Index: -4.0900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0847
Cell Significance Index: -1.2500 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.0905
Cell Significance Index: -0.9600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0958
Cell Significance Index: -13.1500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1021
Cell Significance Index: -11.7000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1043
Cell Significance Index: -4.2800 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.1147
Cell Significance Index: -1.1600 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.1299
Cell Significance Index: -1.3800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1320
Cell Significance Index: -17.0500 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1529
Cell Significance Index: -3.8200 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.1596
Cell Significance Index: -0.9900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1697
Cell Significance Index: -6.2300 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: -0.1786
Cell Significance Index: -1.0700 - Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: -0.1816
Cell Significance Index: -1.5700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1817
Cell Significance Index: -2.0600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1893
Cell Significance Index: -14.5300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2249
Cell Significance Index: -16.7600 - Cell Name: stem cell (CL0000034)
Fold Change: -0.2394
Cell Significance Index: -1.7400 - Cell Name: goblet cell (CL0000160)
Fold Change: -0.2421
Cell Significance Index: -2.1900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2430
Cell Significance Index: -5.0400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2486
Cell Significance Index: -15.2800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2762
Cell Significance Index: -15.5000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2786
Cell Significance Index: -12.9900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2974
Cell Significance Index: -15.4900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.3096
Cell Significance Index: -9.1200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3151
Cell Significance Index: -16.3700 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.3166
Cell Significance Index: -4.2200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3329
Cell Significance Index: -20.9800 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: -0.3403
Cell Significance Index: -3.5100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3475
Cell Significance Index: -15.3700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.3716
Cell Significance Index: -5.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3932
Cell Significance Index: -18.4800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3956
Cell Significance Index: -13.8600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4046
Cell Significance Index: -15.3200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.4194
Cell Significance Index: -6.3200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4356
Cell Significance Index: -14.2600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4584
Cell Significance Index: -14.6000 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.5529
Cell Significance Index: -10.8100 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.5541
Cell Significance Index: -9.1300 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: -0.5825
Cell Significance Index: -7.0900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.5835
Cell Significance Index: -6.0400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.5913
Cell Significance Index: -14.7500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.5951
Cell Significance Index: -17.0600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.6288
Cell Significance Index: -16.7900 - Cell Name: choroid plexus epithelial cell (CL0000706)
Fold Change: -0.6563
Cell Significance Index: -7.8100 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.6659
Cell Significance Index: -13.5500 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.6741
Cell Significance Index: -16.8100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.6753
Cell Significance Index: -14.5900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.6947
Cell Significance Index: -16.6600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.7034
Cell Significance Index: -14.9300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.7221
Cell Significance Index: -15.0700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.7439
Cell Significance Index: -14.7100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.7487
Cell Significance Index: -20.3800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.7556
Cell Significance Index: -15.1700 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.7578
Cell Significance Index: -14.9200 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: -0.7645
Cell Significance Index: -5.3800 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -0.7793
Cell Significance Index: -15.5400 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.7918
Cell Significance Index: -19.1800 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.7943
Cell Significance Index: -13.3800 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: -0.7981
Cell Significance Index: -8.1400 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.8166
Cell Significance Index: -17.0300 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.8281
Cell Significance Index: -11.4900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1817482593
Symbol: CEAM5_HUMAN
Name: Carcinoembryonic antigen-related cell adhesion molecule 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3670312
Title: Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen.
PubMed ID: 3670312
PubMed ID: 3220478
Title: Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.
PubMed ID: 3220478
PubMed ID: 2342461
Title: Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.
PubMed ID: 2342461
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 3814146
Title: Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence.
PubMed ID: 3814146
PubMed ID: 3033671
Title: Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure.
PubMed ID: 3033671
PubMed ID: 2803308
Title: Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.
PubMed ID: 2803308
PubMed ID: 2317824
Title: Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.
PubMed ID: 2317824
PubMed ID: 10436421
Title: Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat.
PubMed ID: 10436421
DOI: 10.1159/000030075
PubMed ID: 10910050
Title: Human carcinoembryonic antigen functions as a general inhibitor of anoikis.
PubMed ID: 10910050
PubMed ID: 10864933
Title: Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion.
PubMed ID: 10864933
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 26483485
Title: Diverse oligomeric states of CEACAM IgV domains.
PubMed ID: 26483485
PubMed ID: 10854848
Title: Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23.
PubMed ID: 10854848
PubMed ID: 18086185
Title: Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation.
PubMed ID: 18086185
Sequence Information:
- Length: 702
- Mass: 76796
- Checksum: 6299AE26CDDBDB5C
- Sequence:
MESPSAPPHR WCIPWQRLLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNRQII GYVIGTQQAT PGPAYSGREI IYPNASLLIQ NIIQNDTGFY TLHVIKSDLV NEEATGQFRV YPELPKPSIS SNNSKPVEDK DAVAFTCEPE TQDATYLWWV NNQSLPVSPR LQLSNGNRTL TLFNVTRNDT ASYKCETQNP VSARRSDSVI LNVLYGPDAP TISPLNTSYR SGENLNLSCH AASNPPAQYS WFVNGTFQQS TQELFIPNIT VNNSGSYTCQ AHNSDTGLNR TTVTTITVYA EPPKPFITSN NSNPVEDEDA VALTCEPEIQ NTTYLWWVNN QSLPVSPRLQ LSNDNRTLTL LSVTRNDVGP YECGIQNELS VDHSDPVILN VLYGPDDPTI SPSYTYYRPG VNLSLSCHAA SNPPAQYSWL IDGNIQQHTQ ELFISNITEK NSGLYTCQAN NSASGHSRTT VKTITVSAEL PKPSISSNNS KPVEDKDAVA FTCEPEAQNT TYLWWVNGQS LPVSPRLQLS NGNRTLTLFN VTRNDARAYV CGIQNSVSAN RSDPVTLDVL YGPDTPIISP PDSSYLSGAN LNLSCHSASN PSPQYSWRIN GIPQQHTQVL FIAKITPNNN GTYACFVSNL ATGRNNSIVK SITVSASGTS PGLSAGATVG IMIGVLVGVA LI
Genular Protein ID: 1008400546
Symbol: Q53G30_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
Sequence Information:
- Length: 702
- Mass: 76868
- Checksum: 62992426CDDABB5C
- Sequence:
MESPSAPPHR WCIPWQRLLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLVHNLPQ HLFGYSWYKG ERVDGNRQII GYVIGTQQAT PGPAYSGREI IYPNASLLIQ NIIQNDTGFY TLHVIKSDLV NEEATGQFRV YPELPKPSIS SNNSKPVEDK DAVAFTCEPE TQDATYLWWV NNQSLPVSPR LQLSNGNRTL TLFNVTRNDT ASYKCETQNP VSARRSDSVI LNVLYGPDAP TISPLNTSYR SGENLNLSCH AASNPPAQYS WFVNGTFQQS TQELFIPNIT VNNSGSYTCQ AHNSDTGLNR TTVTTITVYA EPPKPFITSN NSNPVEDEDA VALTCEPEIQ NTTYLWWVNN QSLPVSPRLQ LSNDNRTLTL LSVTRNDVGP YECGIQNELS VDHSDPVILN VLYGPDDPTI SPSYTYYRPG VNLSLSCHAA SNPPAQYSWL IDENIQQHTQ ELFISNITEK NSGLYTCQAN NSASGHSRTT VKTITVSAEL PKPSISSNNS KPVEDKDAVA FTCEPEAQNT TYLWWVNGQS LPVSPRLQLS NGNRTLTLFN VTRNDARAYV CGIQNSVSAN RSDPVTLDVL YGPDTPIISP PDSSYLSGAN LNLSCHSASN PSPQYSWRIN GIPQQHTQVL FIAKITPNNN GTYACFVSNL ATGRNNSIVK SITVSASGTS PGLSAGATVG IMIGVLVGVA LI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.