Details for: NXF1
Associated with
Other Information
Genular Protein ID: 31446091
Symbol: NXF1_HUMAN
Name: Nuclear RNA export factor 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10202158
Title: TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus.
PubMed ID: 10202158
PubMed ID: 10323864
Title: The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences.
PubMed ID: 10323864
PubMed ID: 10454577
Title: Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs.
PubMed ID: 10454577
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9175835
Title: Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregation.
PubMed ID: 9175835
PubMed ID: 9660949
Title: TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus.
PubMed ID: 9660949
PubMed ID: 10228171
Title: The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human.
PubMed ID: 10228171
PubMed ID: 10924507
Title: Specific interaction between RNA helicase A and Tap, two cellular proteins that bind to the constitutive transport element of type D retrovirus.
PubMed ID: 10924507
PubMed ID: 11259411
Title: Overexpression of TAP/p15 heterodimers bypasses nuclear retention and stimulates nuclear mRNA export.
PubMed ID: 11259411
PubMed ID: 10668806
Title: The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.
PubMed ID: 10668806
PubMed ID: 11256625
Title: Prediction of structural domains of TAP reveals details of its interaction with p15 and nucleoporins.
PubMed ID: 11256625
PubMed ID: 11707413
Title: Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex.
PubMed ID: 11707413
PubMed ID: 11546873
Title: Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex.
PubMed ID: 11546873
PubMed ID: 11546874
Title: Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.
PubMed ID: 11546874
PubMed ID: 14729961
Title: RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export.
PubMed ID: 14729961
PubMed ID: 14730019
Title: eIF4A3 is a novel component of the exon junction complex.
PubMed ID: 14730019
DOI: 10.1261/rna.5230104
PubMed ID: 17001072
Title: RNA-binding motif protein 15 binds to the RNA transport element RTE and provides a direct link to the NXF1 export pathway.
PubMed ID: 17001072
PubMed ID: 18596238
Title: The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control.
PubMed ID: 18596238
PubMed ID: 18364396
Title: Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP.
PubMed ID: 18364396
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19836239
Title: UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.
PubMed ID: 19836239
PubMed ID: 19165146
Title: Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA.
PubMed ID: 19165146
DOI: 10.1038/emboj.2009.5
PubMed ID: 19586903
Title: The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of the nuclear export receptor NXF1.
PubMed ID: 19586903
PubMed ID: 19864460
Title: Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.
PubMed ID: 19864460
PubMed ID: 18936162
Title: Fragile X mental retardation protein FMRP binds mRNAs in the nucleus.
PubMed ID: 18936162
DOI: 10.1128/mcb.01377-08
PubMed ID: 19324961
Title: Assembly and mobility of exon-exon junction complexes in living cells.
PubMed ID: 19324961
DOI: 10.1261/rna.1387009
PubMed ID: 19369354
Title: The cellular RNA export receptor TAP/NXF1 is required for ICP27-mediated export of herpes simplex virus 1 RNA, but the TREX complex adaptor protein Aly/REF appears to be dispensable.
PubMed ID: 19369354
DOI: 10.1128/jvi.00375-09
PubMed ID: 19793817
Title: Epstein-Barr virus protein EB2 contains an N-terminal transferable nuclear export signal that promotes nucleocytoplasmic export by directly binding TAP/NXF1.
PubMed ID: 19793817
DOI: 10.1128/jvi.01276-09
PubMed ID: 20005110
Title: mRNA export from mammalian cell nuclei is dependent on GANP.
PubMed ID: 20005110
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21699900
Title: Facioscapulohumeral muscular dystrophy region gene 1 is a dynamic RNA-associated and actin-bundling protein.
PubMed ID: 21699900
PubMed ID: 22893130
Title: TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export.
PubMed ID: 22893130
DOI: 10.1038/ncomms2005
PubMed ID: 23299939
Title: Chtop is a component of the dynamic TREX mRNA export complex.
PubMed ID: 23299939
PubMed ID: 23591820
Title: The human TREX-2 complex is stably associated with the nuclear pore basket.
PubMed ID: 23591820
DOI: 10.1242/jcs.118000
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23826332
Title: Mapping interactions between mRNA export factors in living cells.
PubMed ID: 23826332
PubMed ID: 25662211
Title: Luzp4 defines a new mRNA export pathway in cancer cells.
PubMed ID: 25662211
DOI: 10.1093/nar/gkv070
PubMed ID: 28984244
Title: YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs.
PubMed ID: 28984244
DOI: 10.7554/elife.31311
PubMed ID: 31940815
Title: The Ebola Virus Nucleoprotein Recruits the Nuclear RNA Export Factor NXF1 into Inclusion Bodies to Facilitate Viral Protein Expression.
PubMed ID: 31940815
DOI: 10.3390/cells9010187
PubMed ID: 11060011
Title: The structure of the mRNA export factor TAP reveals a cis arrangement of a non-canonical RNP domain and an LRR domain.
PubMed ID: 11060011
PubMed ID: 11583626
Title: Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
PubMed ID: 11583626
PubMed ID: 12581645
Title: Structural basis for the interaction between the Tap/NXF1 UBA domain and FG nucleoporins at 1A resolution.
PubMed ID: 12581645
PubMed ID: 11875519
Title: Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1.
PubMed ID: 11875519
DOI: 10.1038/nsb773
Sequence Information:
- Length: 619
- Mass: 70182
- Checksum: 338872AADA789FBF
- Sequence:
MADEGKSYSE HDDERVNFPQ RKKKGRGPFR WKYGEGNRRS GRGGSGIRSS RLEEDDGDVA MSDAQDGPRV RYNPYTTRPN RRGDTWHDRD RIHVTVRRDR APPERGGAGT SQDGTSKNWF KITIPYGRKY DKAWLLSMIQ SKCSVPFTPI EFHYENTRAQ FFVEDASTAS ALKAVNYKIL DRENRRISII INSSAPPHTI LNELKPEQVE QLKLIMSKRY DGSQQALDLK GLRSDPDLVA QNIDVVLNRR SCMAATLRII EENIPELLSL NLSNNRLYRL DDMSSIVQKA PNLKILNLSG NELKSERELD KIKGLKLEEL WLDGNSLCDT FRDQSTYISA IRERFPKLLR LDGHELPPPI AFDVEAPTTL PPCKGSYFGT ENLKSLVLHF LQQYYAIYDS GDRQGLLDAY HDGACCSLSI PFIPQNPARS SLAEYFKDSR NVKKLKDPTL RFRLLKHTRL NVVAFLNELP KTQHDVNSFV VDISAQTSTL LCFSVNGVFK EVDGKSRDSL RAFTRTFIAV PASNSGLCIV NDELFVRNAS SEEIQRAFAM PAPTPSSSPV PTLSPEQQEM LQAFSTQSGM NLEWSQKCLQ DNNWDYTRSA QAFTHLKAKG EIPEVAFMK
Genular Protein ID: 2360233510
Symbol: Q59E96_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 369
- Mass: 41852
- Checksum: 22790CB637B60811
- Sequence:
RPAPEPALDL RCGMADEGKS YSEHDDERVN FPQRKKKGRG PFRWKYGEGN RRSGRGGSGI RSSRLEEDDG DVAMSDAQDG PRVRYNPYTT RPNRRGDTWH DRDRIHVTVR RDRAPPERGG AGTSQDGTSK NWFKITIPYG RKYDKAWLLS MIQSKCSVPF TPIEFHYENT RAQFFVEDAS TASALKAVNY KILDRENRRI SIIINSSAPP HTILNELKPE QVEQLKLIMS KRYDGSQQAL DLKGLRSDPD LVAQNIDVVL NRRSCMAATL RIIEENIPEL LSLNLSNNRL YRLDDMSSIV QKAPNLKILN LSGNELKSER ELDKIKGLKL EELWLDGNSL CDTFRDQSTY IRSVVACVSP PGDLHPLGG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.