LRRC41 | ENSG00000132128 | NCBI 10489

Details for: LRRC41

Gene ID: 10489

Symbol: LRRC41

Ensembl ID: ENSG00000132128

Description: leucine rich repeat containing 41

Associated with

Adaptive immune system
(R-HSA-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-HSA-983168)
Class i mhc mediated antigen processing & presentation
(R-HSA-983169)
Immune system
(R-HSA-168256)
Metabolism of proteins
(R-HSA-392499)
Neddylation
(R-HSA-8951664)
Post-translational protein modification
(R-HSA-597592)
Rhobtb3 atpase cycle
(R-HSA-9706019)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Nucleus
(GO:0005634)
Protein binding
(GO:0005515)
Protein ubiquitination
(GO:0016567)

Other Information

Proteins

Leucine-rich repeat-containing protein 41

Genular Protein ID: 2319059934

Symbol: LRC41_HUMAN

Name: Leucine-rich repeat-containing protein 41

UniProtKB Accession Codes:

Q15345 A8K5G8 Q3MJ96 Q5TDF5 Q71RA8 Q9BSM0

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15498874

Title: Large-scale cDNA transfection screening for genes related to cancer development and progression.

PubMed ID: 15498874

DOI: 10.1073/pnas.0404089101

PubMed ID: 11384984

Title: Muf1, a novel elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.

PubMed ID: 11384984

DOI: 10.1074/jbc.m103093200

PubMed ID: 15601820

Title: VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.

PubMed ID: 15601820

DOI: 10.1101/gad.1252404

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 812
Mass: 88650
Checksum: 9356F26D014B436A
Sequence:

MAAPEAWRAR SCWFCEVAAA TTMEATSREA APAKSSASGP NAPPALFELC GRAVSAHMGV 
LESGVWALPG PILQSILPLL NIYYLERIEE TALKKGLSTQ AIWRRLWDEL MKTRPSSLES 
VTCWRAKFME AFFSHVLRGT IDVSSDRRLC DQRFSPLLHS SRHVRQLTIC NMLQGATELV 
AEPNRRVLET LASSLHTLKF RHLLFSDVAA QQSLRQLLHQ LIHHGAVSQV SLYSWPVPES 
ALFILILTMS AGFWQPGPGG PPCRLCGEAS RGRAPSRDEG SLLLGSRRPR RDAAERCAAA 
LMASRRKSEA KQMPRAAPAT RVTRRSTQES LTAGGTDLKR ELHPPATSHE APGTKRSPSA 
PAATSSASSS TSSYKRAPAS SAPQPKPLKR FKRAAGKKGA RTRQGPGAES EDLYDFVFIV 
AGEKEDGEEM EIGEVACGAL DGSDPSCLGL PALEASQRFR SISTLELFTV PLSTEAALTL 
CHLLSSWVSL ESLTLSYNGL GSNIFRLLDS LRALSGQAGC RLRALHLSDL FSPLPILELT 
RAIVRALPLL RVLSIRVDHP SQRDNPGVPG NAGPPSHIIG DEEIPENCLE QLEMGFPRGA 
QPAPLLCSVL KASGSLQQLS LDSATFASPQ DFGLVLQTLK EYNLALKRLS FHDMNLADCQ 
SEVLFLLQNL TLQEITFSFC RLFEKRPAQF LPEMVAAMKG NSTLKGLRLP GNRLGNAGLL 
ALADVFSEDS SSSLCQLDIS SNCIKPDGLL EFAKRLERWG RGAFGHLRLF QNWLDQDAVT 
AREAIRRLRA TCHVVSDSWD SSQAFADYVS TM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: LRRC41

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Large-scale cDNA transfection screening for genes related to cancer development and progression. PubMed ID: 15498874

Muf1, a novel elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. PubMed ID: 11384984

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. PubMed ID: 15601820

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. PubMed ID: 17525332

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Initial characterization of the human central proteome. PubMed ID: 21269460

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569