Details for: CARM1

Gene ID: 10498

Symbol: CARM1

Ensembl ID: ENSG00000142453

Description: coactivator associated arginine methyltransferase 1

Associated with

Other Information

Genular Protein ID: 2428170889

Symbol: CARM1_HUMAN

Name: Histone-arginine methyltransferase CARM1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12237300

Title: Lipopolysaccharide-induced methylation of HuR, an mRNA-stabilizing protein, by CARM1. Coactivator-associated arginine methyltransferase.

PubMed ID: 12237300

DOI: 10.1074/jbc.m206187200

PubMed ID: 15221992

Title: Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen-independent status.

PubMed ID: 15221992

DOI: 10.1002/cncr.20327

PubMed ID: 15471871

Title: Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1.

PubMed ID: 15471871

DOI: 10.1074/jbc.m410021200

PubMed ID: 15731352

Title: Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination.

PubMed ID: 15731352

DOI: 10.1073/pnas.0407159102

PubMed ID: 17005681

Title: Coactivator-associated arginine methyltransferase 1 enhances transcriptional activity of the human T-cell lymphotropic virus type 1 long terminal repeat through direct interaction with Tax.

PubMed ID: 17005681

DOI: 10.1128/jvi.00186-06

PubMed ID: 16497732

Title: Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.

PubMed ID: 16497732

DOI: 10.1210/me.2005-0365

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19405910

Title: Kinetic analysis of human protein arginine N-methyltransferase 2: formation of monomethyl- and asymmetric dimethyl-arginine residues on histone H4.

PubMed ID: 19405910

DOI: 10.1042/bj20090268

PubMed ID: 19843527

Title: Biochemical control of CARM1 enzymatic activity by phosphorylation.

PubMed ID: 19843527

DOI: 10.1074/jbc.m109.065524

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 33412112

Title: CARM1 regulates replication fork speed and stress response by stimulating PARP1.

PubMed ID: 33412112

DOI: 10.1016/j.molcel.2020.12.010

PubMed ID: 34480022

Title: Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia.

PubMed ID: 34480022

DOI: 10.1038/s41419-021-04115-7

PubMed ID: 21410432

Title: Structural basis for CARM1 inhibition by indole and pyrazole inhibitors.

PubMed ID: 21410432

DOI: 10.1042/bj20102161

Sequence Information:

  • Length: 608
  • Mass: 65854
  • Checksum: 094AC60D4A70B263
  • Sequence:
  • MAAAAAAVGP GAGGAGSAVP GGAGPCATVS VFPGARLLTI GDANGEIQRH AEQQALRLEV 
    RAGPDSAGIA LYSHEDVCVF KCSVSRETEC SRVGKQSFII TLGCNSVLIQ FATPNDFCSF 
    YNILKTCRGH TLERSVFSER TEESSAVQYF QFYGYLSQQQ NMMQDYVRTG TYQRAILQNH 
    TDFKDKIVLD VGCGSGILSF FAAQAGARKI YAVEASTMAQ HAEVLVKSNN LTDRIVVIPG 
    KVEEVSLPEQ VDIIISEPMG YMLFNERMLE SYLHAKKYLK PSGNMFPTIG DVHLAPFTDE 
    QLYMEQFTKA NFWYQPSFHG VDLSALRGAA VDEYFRQPVV DTFDIRILMA KSVKYTVNFL 
    EAKEGDLHRI EIPFKFHMLH SGLVHGLAFW FDVAFIGSIM TVWLSTAPTE PLTHWYQVRC 
    LFQSPLFAKA GDTLSGTCLL IANKRQSYDI SIVAQVDQTG SKSSNLLDLK NPFFRYTGTT 
    PSPPPGSHYT SPSENMWNTG STYNLSSGMA VAGMPTAYDL SSVIASGSSV GHNNLIPLAN 
    TGIVNHTHSR MGSIMSTGIV QGSSGAQGSG GGSTSAHYAV NSQFTMGGPA ISMASPMSIP 
    TNTMHYGS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.