Details for: FBLN5

Gene ID: 10516

Symbol: FBLN5

Ensembl ID: ENSG00000140092

Description: fibulin 5

Associated with

Other Information

Genular Protein ID: 3831761225

Symbol: FBLN5_HUMAN

Name: Fibulin-5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10428823

Title: DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries.

PubMed ID: 10428823

DOI: 10.1074/jbc.274.32.22476

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15790312

Title: Fibulin-5 interacts with fibrillin-1 molecules and microfibrils.

PubMed ID: 15790312

DOI: 10.1042/bj20050368

PubMed ID: 17255108

Title: Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

PubMed ID: 17255108

DOI: 10.1074/jbc.m608204200

PubMed ID: 19570982

Title: Differential regulation of elastic fiber formation by fibulin-4 and -5.

PubMed ID: 19570982

DOI: 10.1074/jbc.m109.019364

PubMed ID: 19617354

Title: Fibulin 5 forms a compact dimer in physiological solutions.

PubMed ID: 19617354

DOI: 10.1074/jbc.m109.011627

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12189163

Title: Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa.

PubMed ID: 12189163

DOI: 10.1093/hmg/11.18.2113

PubMed ID: 12618961

Title: Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene.

PubMed ID: 12618961

DOI: 10.1086/373940

PubMed ID: 15269314

Title: Missense variations in the fibulin 5 gene and age-related macular degeneration.

PubMed ID: 15269314

DOI: 10.1056/nejmoa040833

PubMed ID: 17035250

Title: Fibulin-5 mutations: mechanisms of impaired elastic fiber formation in recessive cutis laxa.

PubMed ID: 17035250

DOI: 10.1093/hmg/ddl414

PubMed ID: 16652333

Title: Reduced secretion of fibulin 5 in age-related macular degeneration and cutis laxa.

PubMed ID: 16652333

DOI: 10.1002/humu.20344

PubMed ID: 16691202

Title: Homozygous missense mutation in fibulin-5 in an Iranian autosomal recessive cutis laxa pedigree and associated haplotype.

PubMed ID: 16691202

DOI: 10.1038/sj.jid.5700247

PubMed ID: 18185537

Title: A p.C217R mutation in fibulin-5 from cutis laxa patients is associated with incomplete extracellular matrix formation in a skin equivalent model.

PubMed ID: 18185537

DOI: 10.1038/sj.jid.5701211

PubMed ID: 19194475

Title: An autosomal-recessive form of cutis laxa is due to homozygous elastin mutations, and the phenotype may be modified by a heterozygous fibulin 5 polymorphism.

PubMed ID: 19194475

DOI: 10.1038/jid.2008.450

PubMed ID: 20007835

Title: Structural effects of fibulin 5 missense mutations associated with age-related macular degeneration and cutis laxa.

PubMed ID: 20007835

DOI: 10.1167/iovs.09-4620

PubMed ID: 20599547

Title: Biophysical characterisation of fibulin-5 proteins associated with disease.

PubMed ID: 20599547

DOI: 10.1016/j.jmb.2010.06.039

PubMed ID: 21576112

Title: Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin.

PubMed ID: 21576112

DOI: 10.1093/brain/awr076

PubMed ID: 23328402

Title: Czech family confirms the link between FBLN5 and Charcot-Marie-Tooth type 1 neuropathy.

PubMed ID: 23328402

DOI: 10.1093/brain/aws333

Sequence Information:

  • Length: 448
  • Mass: 50180
  • Checksum: 19FCA51FDA328003
  • Sequence:
  • MPGIKRILTV TILALCLPSP GNAQAQCTNG FDLDRQSGQC LDIDECRTIP EACRGDMMCV 
    NQNGGYLCIP RTNPVYRGPY SNPYSTPYSG PYPAAAPPLS APNYPTISRP LICRFGYQMD 
    ESNQCVDVDE CATDSHQCNP TQICINTEGG YTCSCTDGYW LLEGQCLDID ECRYGYCQQL 
    CANVPGSYSC TCNPGFTLNE DGRSCQDVNE CATENPCVQT CVNTYGSFIC RCDPGYELEE 
    DGVHCSDMDE CSFSEFLCQH ECVNQPGTYF CSCPPGYILL DDNRSCQDIN ECEHRNHTCN 
    LQQTCYNLQG GFKCIDPIRC EEPYLRISDN RCMCPAENPG CRDQPFTILY RDMDVVSGRS 
    VPADIFQMQA TTRYPGAYYI FQIKSGNEGR EFYMRQTGPI SATLVMTRPI KGPREIQLDL 
    EMITVNTVIN FRGSSVIRLR IYVSQYPF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.