Details for: CIB2

Gene ID: 10518

Symbol: CIB2

Ensembl ID: ENSG00000136425

Description: calcium and integrin binding family member 2

Associated with

Other Information

Genular Protein ID: 2972014505

Symbol: CIB2_HUMAN

Name: Calcium and integrin-binding family member 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9931475

Title: Structure, expression profile and chromosomal location of an isolog of DNA-PKcs interacting protein (KIP) gene.

PubMed ID: 9931475

DOI: 10.1016/s0167-4781(98)00253-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 22779914

Title: Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.

PubMed ID: 22779914

DOI: 10.1139/o2012-021

PubMed ID: 31636333

Title: Oligomeric state, hydrodynamic properties and target recognition of human Calcium and Integrin Binding protein 2 (CIB2).

PubMed ID: 31636333

DOI: 10.1038/s41598-019-51573-3

PubMed ID: 23023331

Title: Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.

PubMed ID: 23023331

DOI: 10.1038/ng.2426

PubMed ID: 26416264

Title: PDZD7 and hearing loss: More than just a modifier.

PubMed ID: 26416264

DOI: 10.1002/ajmg.a.37274

PubMed ID: 26426422

Title: A novel c-terminal CIB2 (calcium and integrin binding protein 2) mutation associated with non-syndromic hearing loss in a hispanic family.

PubMed ID: 26426422

DOI: 10.1371/journal.pone.0133082

PubMed ID: 26173970

Title: Novel and recurrent CIB2 variants, associated with nonsyndromic deafness, do not affect calcium buffering and localization in hair cells.

PubMed ID: 26173970

DOI: 10.1038/ejhg.2015.157

PubMed ID: 29084757

Title: CIB2, defective in isolated deafness, is key for auditory hair cell mechanotransduction and survival.

PubMed ID: 29084757

DOI: 10.15252/emmm.201708087

PubMed ID: 28663585

Title: CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.

PubMed ID: 28663585

DOI: 10.1038/s41467-017-00061-1

PubMed ID: 34089643

Title: CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells.

PubMed ID: 34089643

DOI: 10.1016/j.neuron.2021.05.007

Sequence Information:

  • Length: 187
  • Mass: 21644
  • Checksum: D51F6C25AD381BEF
  • Sequence:
  • MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HSRFYELAPN LVPMDYRKSP IVHVPMSLII 
    QMPELRENPF KERIVAAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD 
    NFICKEDLEL TLARLTKSEL DEEEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL 
    STFHIRI

Genular Protein ID: 1468083896

Symbol: H0YKC8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

Sequence Information:

  • Length: 167
  • Mass: 19016
  • Checksum: E6C639315075BFDB
  • Sequence:
  • MDYRKSPIVH VPMSLIIQMP ELRENPFKER IVAAFSEDGE GNLTFNDFVD MFSVLCESAP 
    RELKANYAFK IYDFNTDNFI CKEDLELTLA RLTKSELDEE EVVLVCDKVI EEADLDGDGK 
    LGFADFEDMI AKAPDFLRCC HYRGRAWAGQ SRAGRDVGAE APITRYL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.