Details for: CIB1
Associated with
Other Information
Genular Protein ID: 3329042991
Symbol: CIB1_HUMAN
Name: Calcium and integrin-binding protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9030514
Title: Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain.
PubMed ID: 9030514
PubMed ID: 9372844
Title: Interaction between DNA-dependent protein kinase and a novel protein, KIP.
PubMed ID: 9372844
PubMed ID: 10826701
Title: Genomic structure of mouse and human genes for DNA-PKcs interacting protein (KIP).
PubMed ID: 10826701
PubMed ID: 23503467
Title: A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis.
PubMed ID: 23503467
DOI: 10.1038/onc.2013.43
PubMed ID: 19054851
Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.
PubMed ID: 19054851
DOI: 10.1038/nmeth.1273
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10477286
Title: Calcium-dependent properties of CIB binding to the integrin alphaIIb cytoplasmic domain and translocation to the platelet cytoskeleton.
PubMed ID: 10477286
DOI: 10.1042/bj3420729
PubMed ID: 10366599
Title: A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein.
PubMed ID: 10366599
PubMed ID: 11323029
Title: The interaction of the calcium- and integrin-binding protein (CIBP) with the coagulation factor VIII.
PubMed ID: 11323029
PubMed ID: 11856312
Title: NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube.
PubMed ID: 11856312
PubMed ID: 11756406
Title: The small GTPase Rac3 interacts with the integrin-binding protein CIB and promotes integrin alpha(IIb)beta(3)-mediated adhesion and spreading.
PubMed ID: 11756406
PubMed ID: 12011095
Title: EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.
PubMed ID: 12011095
PubMed ID: 12023286
Title: Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain.
PubMed ID: 12023286
PubMed ID: 12714504
Title: Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen.
PubMed ID: 12714504
PubMed ID: 14992593
Title: Metal ion binding properties and conformational states of calcium- and integrin-binding protein.
PubMed ID: 14992593
DOI: 10.1021/bi035432b
PubMed ID: 15475008
Title: Calcium binding sequences in calmyrin regulates interaction with presenilin-2.
PubMed ID: 15475008
PubMed ID: 12881299
Title: Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen.
PubMed ID: 12881299
PubMed ID: 15933764
Title: Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.
PubMed ID: 15933764
PubMed ID: 15685448
Title: G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell.
PubMed ID: 15685448
PubMed ID: 16061695
Title: Essential role of CIB1 in regulating PAK1 activation and cell migration.
PubMed ID: 16061695
PubMed ID: 15883187
Title: Calcium- and magnesium-dependent interactions between calcium- and integrin-binding protein and the integrin alphaIIb cytoplasmic domain.
PubMed ID: 15883187
DOI: 10.1110/ps.041312805
PubMed ID: 16723353
Title: CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel.
PubMed ID: 16723353
PubMed ID: 16418530
Title: CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation.
PubMed ID: 16418530
PubMed ID: 18627437
Title: Sweet taste receptor interacting protein CIB1 is a general inhibitor of InsP3-dependent Ca2+ release in vivo.
PubMed ID: 18627437
PubMed ID: 19805025
Title: CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1.
PubMed ID: 19805025
PubMed ID: 19388079
Title: Auxiliary Ca2+ binding sites can influence the structure of CIB1.
PubMed ID: 19388079
DOI: 10.1002/pro.104
PubMed ID: 19854831
Title: Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1.
PubMed ID: 19854831
PubMed ID: 20639889
Title: CIB1 is a regulator of pathological cardiac hypertrophy.
PubMed ID: 20639889
DOI: 10.1038/nm.2181
PubMed ID: 21215777
Title: Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.
PubMed ID: 21215777
PubMed ID: 20951827
Title: Calcium- and integrin-binding protein 1 regulates microtubule organization and centrosome segregation through polo like kinase 3 during cell cycle progression.
PubMed ID: 20951827
PubMed ID: 20473878
Title: Calcium-dependent inhibition of polo-like kinase 3 activity by CIB1 in breast cancer cells.
PubMed ID: 20473878
DOI: 10.1002/ijc.25388
PubMed ID: 21748785
Title: Contra-regulation of calcium- and integrin-binding protein 1-induced cell migration on fibronectin by PAK1 and MAP kinase signaling.
PubMed ID: 21748785
DOI: 10.1002/jcb.23255
PubMed ID: 21264284
Title: Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells.
PubMed ID: 21264284
PubMed ID: 22779914
Title: Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.
PubMed ID: 22779914
DOI: 10.1139/o2012-021
PubMed ID: 24011356
Title: Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity.
PubMed ID: 24011356
DOI: 10.1021/bi400678y
PubMed ID: 22964641
Title: CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signaling.
PubMed ID: 22964641
DOI: 10.1038/onc.2012.408
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 30068544
Title: The human CIB1-EVER1-EVER2 complex governs keratinocyte-intrinsic immunity to beta-papillomaviruses.
PubMed ID: 30068544
DOI: 10.1084/jem.20170308
PubMed ID: 10822252
Title: Structures of the platelet calcium- and integrin-binding protein and the alphaIIb-integrin cytoplasmic domain suggest a mechanism for calcium-regulated recognition; homology modelling and NMR studies.
PubMed ID: 10822252
DOI: 10.1002/(sici)1099-1352(200003/04)13:2<83::aid-jmr491>3.0.co;2-a
PubMed ID: 15574431
Title: Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins.
PubMed ID: 15574431
PubMed ID: 15840829
Title: The crystal structure of calcium- and integrin-binding protein 1: insights into redox regulated functions.
PubMed ID: 15840829
DOI: 10.1110/ps.041270805
PubMed ID: 21388953
Title: Solution structures of Ca2+-CIB1 and Mg2+-CIB1 and their interactions with the platelet integrin alphaIIb cytoplasmic domain.
PubMed ID: 21388953
PubMed ID: 22283712
Title: Structural basis for the activation of platelet integrin alphaIIbbeta3 by calcium- and integrin-binding protein 1.
PubMed ID: 22283712
DOI: 10.1021/ja2111306
Sequence Information:
- Length: 191
- Mass: 21703
- Checksum: 9AA19A0DE7AA1E05
- Sequence:
MGGSGSRLSK ELLAEYQDLT FLTKQEILLA HRRFCELLPQ EQRSVESSLR AQVPFEQILS LPELKANPFK ERICRVFSTS PAKDSLSFED FLDLLSVFSD TATPDIKSHY AFRIFDFDDD GTLNREDLSR LVNCLTGEGE DTRLSASEMK QLIDNILEES DIDRDGTINL SEFQHVISRS PDFASSFKIV L
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.