Details for: DDX17
Associated with
Other Information
Genular Protein ID: 3880743842
Symbol: DDX17_HUMAN
Name: Probable ATP-dependent RNA helicase DDX17
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8871553
Title: p72: a human nuclear DEAD box protein highly related to p68.
PubMed ID: 8871553
PubMed ID: 15461802
Title: A genome annotation-driven approach to cloning the human ORFeome.
PubMed ID: 15461802
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 10591208
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 26209609
Title: Systematic determination of human cyclin dependent kinase (CDK)-9 interactome identifies novel functions in RNA splicing mediated by the DEAD box (DDX)-5/17 RNA helicases.
PubMed ID: 26209609
PubMed ID: 17011493
Title: The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation.
PubMed ID: 17011493
PubMed ID: 11250900
Title: A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA.
PubMed ID: 11250900
PubMed ID: 25452582
PubMed ID: 11675387
Title: The mRNA of DEAD box protein p72 is alternatively translated into an 82-kDa RNA helicase.
PubMed ID: 11675387
PubMed ID: 12138182
Title: Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72.
PubMed ID: 12138182
PubMed ID: 12595555
Title: The highly related DEAD box RNA helicases p68 and p72 exist as heterodimers in cells.
PubMed ID: 12595555
DOI: 10.1093/nar/gkg236
PubMed ID: 15298701
Title: The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.
PubMed ID: 15298701
PubMed ID: 15531877
Title: The microprocessor complex mediates the genesis of microRNAs.
PubMed ID: 15531877
DOI: 10.1038/nature03120
PubMed ID: 15660129
Title: The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor.
PubMed ID: 15660129
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17699760
Title: Involvement of RNA helicases p68 and p72 in colon cancer.
PubMed ID: 17699760
PubMed ID: 17226766
Title: Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF.
PubMed ID: 17226766
DOI: 10.1002/jcb.21250
PubMed ID: 17485482
Title: Redundant role of DEAD box proteins p68 (Ddx5) and p72/p82 (Ddx17) in ribosome biogenesis and cell proliferation.
PubMed ID: 17485482
DOI: 10.1093/nar/gkm058
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18279852
Title: Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.
PubMed ID: 18279852
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18334637
Title: p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein.
PubMed ID: 18334637
PubMed ID: 19718048
Title: The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.
PubMed ID: 19718048
DOI: 10.1038/onc.2009.261
PubMed ID: 19995069
Title: Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.
PubMed ID: 19995069
DOI: 10.1021/bi901263m
PubMed ID: 20406972
Title: Estrogen regulation and physiopathologic significance of alternative promoters in breast cancer.
PubMed ID: 20406972
PubMed ID: 20663877
Title: Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.
PubMed ID: 20663877
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21876179
Title: Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation.
PubMed ID: 21876179
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22002106
Title: Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.
PubMed ID: 22002106
PubMed ID: 23022728
Title: Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness.
PubMed ID: 23022728
DOI: 10.1038/nsmb.2390
PubMed ID: 22266867
Title: Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.
PubMed ID: 22266867
DOI: 10.1038/onc.2011.618
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23788676
Title: The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA.
PubMed ID: 23788676
DOI: 10.1093/nar/gkt538
PubMed ID: 24589731
Title: Cell cycle-dependent regulation of Aurora kinase B mRNA by the Microprocessor complex.
PubMed ID: 24589731
PubMed ID: 24581491
Title: Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.
PubMed ID: 24581491
PubMed ID: 25126784
Title: Stem-loop recognition by DDX17 facilitates miRNA processing and antiviral defense.
PubMed ID: 25126784
PubMed ID: 24910439
Title: RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.
PubMed ID: 24910439
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 24275493
Title: The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways.
PubMed ID: 24275493
DOI: 10.1093/nar/gkt1216
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 26030138
Title: Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.
PubMed ID: 26030138
PubMed ID: 27478153
Title: The miRNA biogenesis factors, p72/DDX17 and KHSRP regulate the protein level of Ago2 in human cells.
PubMed ID: 27478153
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 729
- Mass: 80272
- Checksum: C819F53515B1BC39
- Sequence:
MPTGFVAPIL CVLLPSPTRE AATVASATGD SASERESAAP AAAPTAEAPP PSVVTRPEPQ ALPSPAIRAP LPDLYPFGTM RGGGFGDRDR DRDRGGFGAR GGGGLPPKKF GNPGERLRKK KWDLSELPKF EKNFYVEHPE VARLTPYEVD ELRRKKEITV RGGDVCPKPV FAFHHANFPQ YVMDVLMDQH FTEPTPIQCQ GFPLALSGRD MVGIAQTGSG KTLAYLLPAI VHINHQPYLE RGDGPICLVL APTRELAQQV QQVADDYGKC SRLKSTCIYG GAPKGPQIRD LERGVEICIA TPGRLIDFLE SGKTNLRRCT YLVLDEADRM LDMGFEPQIR KIVDQIRPDR QTLMWSATWP KEVRQLAEDF LRDYTQINVG NLELSANHNI LQIVDVCMES EKDHKLIQLM EEIMAEKENK TIIFVETKRR CDDLTRRMRR DGWPAMCIHG DKSQPERDWV LNEFRSGKAP ILIATDVASR GLDVEDVKFV INYDYPNSSE DYVHRIGRTA RSTNKGTAYT FFTPGNLKQA RELIKVLEEA NQAINPKLMQ LVDHRGGGGG GGGRSRYRTT SSANNPNLMY QDECDRRLRG VKDGGRRDSA SYRDRSETDR AGYANGSGYG SPNSAFGAQA GQYTYGQGTY GAAAYGTSSY TAQEYGAGTY GASSTTSTGR SSQSSSQQFS GIGRSGQQPQ PLMSQQFAQP PGATNMIGYM GQTAYQYPPP PPPPPPSRK
Genular Protein ID: 3680867001
Symbol: A0A5H1ZRQ2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10591208
Sequence Information:
- Length: 731
- Mass: 80458
- Checksum: A4851DD1B35A48A2
- Sequence:
MPTGFVAPIL CVLLPSPTRE AATVASATGD SASERESAAP AAAPTAEAPP PSVVTRPEPQ ALPSPAIRAP LPDLYPFGTM RGGGFGDRDR DRDRGGFGAR GGGGLPPKKF GNPGERLRKK KWDLSELPKF EKNFYVEHPE VARLTPYEVD ELRRKKEITV RGGDVCPKPV FAFHHANFPQ YVMDVLMDQH FTEPTPIQCQ GFPLALSGRD MVGIAQTGSG KTLAYLLPAI VHINHQPYLE RGDGPICLVL APTRELAQQV QQVADDYGKC SRLKSTCIYG GAPKGPQIRD LERGVEICIA TPGRLIDFLE SGKTNLRRCT YLVLDEADRM LDMGFEPQIR KIVDQIRPDR QTLMWSATWP KEVRQLAEDF LRDYTQINVG NLELSANHNI LQIVDVCMES EKDHKLIQLM EEIMAEKENK TIIFVETKRR CDDLTRRMRR DGWPAMCIHG DKSQPERDWV LNEFRSGKAP ILIATDVASR GLDVEDVKFV INYDYPNSSE DYVHRIGRTA RSTNKGTAYT FFTPGNLKQA RELIKVLEEA NQAINPKLMQ LVDHRGGGGG GGKGGRSRYR TTSSANNPNL MYQDECDRRL RGVKDGGRRD SASYRDRSET DRAGYANGSG YGSPNSAFGA QAGQYTYGQG TYGAAAYGTS SYTAQEYGAG TYGASSTTST GRSSQSSSQQ FSGIGRSGQQ PQPLMSQQFA QPPGATNMIG YMGQTAYQYP PPPPPPPPSR K
Genular Protein ID: 3786404254
Symbol: Q59F66_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 737
- Mass: 81067
- Checksum: FA5E2A47B8844D1C
- Sequence:
PNLPTGFVAP ILCVLLPSPT REAATVASAT GDSASERESA APAAAPTAEA PPPSVVTRPE PQALPSPAIR APLPDLYPFG TMRGGGFGDR DRDRDRGGFG ARGGGGLPPK KFGNPGERLR KKKWDLSELP KFEKNFYVEH PEVARLTPYE VDELRRKKEI TVRGGDVCPK PVFAFHHANF PQYVMDVLMD QHFTEPTPIQ CQGFPLALSG RDMVGIAQTG SGKTLAYLLP AIVHINHQPY LERGDGPICL VLAPTRELAQ QVQQVADDYG KCSRLKSTCI YGGAPKGPQI RDLERGVEIC IATPGRLIDF LESGKTNLRR CTYLVLDEAD RMLDMGFEPQ IRKIVDQIRP DRQTLMWSAT WPKEVRQLAE DFLRDYTQIN VGNLELSANH NILQIVDVCM ESEKDHKLIQ LMEEIMAEKE NKTIIFVETK RRCDDLTRRM RRDGWPAMCI HGDKSQPERD WVLNEFRSGK APILIATDVA SRGLDVEDVK FVINYDYPNS SEDYVHRIGR TARSTNKGTA YTFFTPGNLK QARELIKVLE EANQAINPKL MQLVDHRGGG GGGGKGGRSR YRTTSSANNP NLMYQDECDR RLRGVKDGGR RDSASYRDRS ETDRAGYANG SGYGSPNSAF GAQAGQYTYG QGTYGAAAYG TSSYTAQEYG AGTYGASSTT STGRSSQSSS QQFSGIGRSG QQPQPLMSQQ FAQPPGATNT LLLLPLLLLH VNETTQVVVT PADLITF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.