Details for: DEAF1

Gene ID: 10522

Symbol: DEAF1

Ensembl ID: ENSG00000177030

Description: DEAF1 transcription factor

Associated with

Other Information

Genular Protein ID: 955192056

Symbol: DEAF1_HUMAN

Name: Deformed epidermal autoregulatory factor 1 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9773984

Title: Characterization of a nuclear deformed epidermal autoregulatory factor-1 (DEAF-1)-related (NUDR) transcriptional regulator protein.

PubMed ID: 9773984

DOI: 10.1210/mend.12.10.0181

PubMed ID: 11705868

Title: Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas.

PubMed ID: 11705868

PubMed ID: 19668219

Title: Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes.

PubMed ID: 19668219

DOI: 10.1038/ni.1773

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10521432

Title: Nuclear DEAF-1-related (NUDR) protein contains a novel DNA binding domain and represses transcription of the heterogeneous nuclear ribonucleoprotein A2/B1 promoter.

PubMed ID: 10521432

DOI: 10.1074/jbc.274.43.30510

PubMed ID: 11427895

Title: The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.

PubMed ID: 11427895

DOI: 10.1038/89675

PubMed ID: 18826651

Title: Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland.

PubMed ID: 18826651

DOI: 10.1186/1471-213x-8-94

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 22442688

Title: Deformed epidermal autoregulatory factor-1 (DEAF1) interacts with the Ku70 subunit of the DNA-dependent protein kinase complex.

PubMed ID: 22442688

DOI: 10.1371/journal.pone.0033404

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24726472

Title: Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems.

PubMed ID: 24726472

DOI: 10.1016/j.ajhg.2014.03.013

PubMed ID: 16527309

Title: Structure and functional analysis of the MYND domain.

PubMed ID: 16527309

DOI: 10.1016/j.jmb.2006.01.087

PubMed ID: 18286714

Title: Retraction notice to 'Structure and functional analysis of the MYND domain' [J. Mol. Biol. (2006) 358, 498-508].

PubMed ID: 18286714

DOI: 10.1016/j.jmb.2008.01.071

PubMed ID: 23372760

Title: Structural and functional analysis of the DEAF-1 and BS69 MYND domains.

PubMed ID: 23372760

DOI: 10.1371/journal.pone.0054715

PubMed ID: 21076407

Title: A de novo paradigm for mental retardation.

PubMed ID: 21076407

DOI: 10.1038/ng.712

PubMed ID: 26048982

Title: Recessive DEAF1 mutation associates with autism, intellectual disability, basal ganglia dysfunction and epilepsy.

PubMed ID: 26048982

DOI: 10.1136/jmedgenet-2015-103083

PubMed ID: 24668509

Title: Novel homozygous DEAF1 variant suspected in causing white matter disease, intellectual disability, and microcephaly.

PubMed ID: 24668509

DOI: 10.1002/ajmg.a.36482

Sequence Information:

  • Length: 565
  • Mass: 59327
  • Checksum: 3BDFEDBF6AD4BDDE
  • Sequence:
  • MEDSDSAAKQ LGLAEAAAVA AAAAVAAAAA AAAGGEAEEP VLSRDEDSEE DADSEAERET 
    PRVTAVAVMA AEPGHMDMGA EALPGPDEAA AAAAFAEVTT VTVANVGAAA DNVFTTSVAN 
    AASISGHVLS GRTALQIGDS LNTEKATLIV VHTDGSIVET TGLKGPAAPL TPGPQSPPTP 
    LAPGQEKGGT KYNWDPSVYD SELPVRCRNI SGTLYKNRLG SGGRGRCIKQ GENWYSPTEF 
    EAMAGRASSK DWKRSIRYAG RPLQCLIQDG ILNPHAASCT CAACCDDMTL SGPVRLFVPY 
    KRRKKENELP TTPVKKDSPK NITLLPATAA TTFTVTPSGQ ITTSGALTFD RASTVEATAV 
    ISESPAQGDV FAGATVQEAS VQPPCRASHP EPHYPGYQDS CQIAPFPEAA LPTSHPKIVL 
    TSLPALAVPP PTPTKAAPPA LVNGLELSEP RSWLYLEEMV NSLLNTAQQL KTLFEQAKHA 
    STYREAATNQ AKIHADAERK EQSCVNCGRE AMSECTGCHK VNYCSTFCQR KDWKDHQHIC 
    GQSAAVTVQA DEVHVAESVM EKVTV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.