Details for: PITRM1
Associated with
Other Information
Genular Protein ID: 862935582
Symbol: PREP_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10360838
Title: Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases.
PubMed ID: 10360838
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10470851
Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10470851
PubMed ID: 16849325
Title: Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP.
PubMed ID: 16849325
PubMed ID: 19196155
Title: Mammalian pitrilysin: substrate specificity and mitochondrial targeting.
PubMed ID: 19196155
DOI: 10.1021/bi8016125
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21621546
Title: Targeting capacity and conservation of PreP homologues localization in mitochondria of different species.
PubMed ID: 21621546
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24931469
Title: Molecular basis of substrate recognition and degradation by human presequence protease.
PubMed ID: 24931469
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26697887
Title: Defective PITRM1 mitochondrial peptidase is associated with Abeta amyloidotic neurodegeneration.
PubMed ID: 26697887
PubMed ID: 29764912
Title: Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy.
PubMed ID: 29764912
PubMed ID: 29383861
Title: Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy.
PubMed ID: 29383861
DOI: 10.1002/pro.3380
Sequence Information:
- Length: 1037
- Mass: 117413
- Checksum: F488389F0E219718
- Sequence:
MWRCGGRQGL CVLRRLSGGH AHHRAWRWNS NRACERALQY KLGDKIHGFT VNQVTSVPEL FLTAVKLTHD DTGARYLHLA REDTNNLFSV QFRTTPMDST GVPHILEHTV LCGSQKYPCR DPFFKMLNRS LSTFMNAFTA SDYTLYPFST QNPKDFQNLL SVYLDATFFP CLRELDFWQE GWRLEHENPS DPQTPLVFKG VVFNEMKGAF TDNERIFSQH LQNRLLPDHT YSVVSGGDPL CIPELTWEQL KQFHATHYHP SNARFFTYGN FPLEQHLKQI HEEALSKFQK IEPSTVVPAQ TPWDKPREFQ ITCGPDSFAT DPSKQTTISV SFLLPDITDT FEAFTLSLLS SLLTSGPNSP FYKALIESGL GTDFSPDVGY NGYTREAYFS VGLQGIAEKD IETVRSLIDR TIDEVVEKGF EDDRIEALLH KIEIQMKHQS TSFGLMLTSY IASCWNHDGD PVELLKLGNQ LAKFRQCLQE NPKFLQEKVK QYFKNNQHKL TLSMRPDDKY HEKQAQVEAT KLKQKVEALS PGDRQQIYEK GLELRSQQSK PQDASCLPAL KVSDIEPTIP VTELDVVLTA GDIPVQYCAQ PTNGMVYFRA FSSLNTLPEE LRPYVPLFCS VLTKLGCGLL DYREQAQQIE LKTGGMSASP HVLPDDSHMD TYEQGVLFSS LCLDRNLPDM MQLWSEIFNN PCFEEEEHFK VLVKMTAQEL ANGIPDSGHL YASIRAGRTL TPAGDLQETF SGMDQVRLMK RIAEMTDIKP ILRKLPRIKK HLLNGDNMRC SVNATPQQMP QTEKAVEDFL RSIGRSKKER RPVRPHTVEK PVPSSSGGDA HVPHGSQVIR KLVMEPTFKP WQMKTHFLMP FPVNYVGECI RTVPYTDPDH ASLKILARLM TAKFLHTEIR EKGGAYGGGA KLSHNGIFTL YSYRDPNTIE TLQSFGKAVD WAKSGKFTQQ DIDEAKLSVF STVDAPVAPS DKGMDHFLYG LSDEMKQAHR EQLFAVSHDK LLAVSDRYLG TGKSTHGLAI LGPENPKIAK DPSWIIQ
Genular Protein ID: 685888882
Symbol: A0A7I2V397_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
Sequence Information:
- Length: 971
- Mass: 109956
- Checksum: A1FFDD2E6972EB1C
- Sequence:
MWRCGGRQGL CVLRRLSGGH AHHRAWRWNS NRACERALQY KLGDKIHGFT VNQVTSVPEL FLTAVKLTHD DTGARYLHLA REDTNNLFSV QFRTTPMDST GVPHILEHTV LCGSQKYPCR DPFFKMLNRS LSTFMNAFTA SDYTLYPFST QNPKDFQNLL SVYLDATFFP CLRELDFWQE GWRLEHENPS DPQTPLVFKG VVFNEMKGAF TDNERIFSQH LQNRLLPDHT YSVVSGGDPL CIPELTWEQL KQFHATHYHP SNARFFTYGN FPLEQHLKQI HEEALSKFQK IEPSTVVPAQ TPWDKPREFQ ITCGPDSFAT DPSKQTTISV SFLLPDITDT FEAFTLSLLS SLLTSGPNSP FYKALIESGL GTDFSPDVGY NGYTREAYFS VGLQGIAEKD IETVRSLIDR TIDEVVEKGF EDDRIEALLH KIEIQMKHQS TSFGLMLTSY IASCWNHDGD PVELLKLGNQ LAKFRQCLQE NPKFLQEKVK QYFKNNQHKL TLSMRPDDKY HEKQAQVEAT KLKQKVEALS PGDRQQIYEK GLELRSQQSK PQDASCLPAL KVSDIEPTIP VTELDVVLTA GDIPVQYCAQ PTNGMVYFRA FSSLNTLPEE LRPYVPLFCS VLTNPCFEEE EHFKVLVKMT AQELANGIPD SGHLYASIRA GRTLTPAGDL QETFSGMDQV RLMKRIAEMT DIKPILRKLP RIKKHLLNGD NMRCSVNATP QQMPQTEKAV EDFLRSIGRS KKERRPVRPH TVEKPVPSSS GGDAHVPHGS QVIRKLVMEP TFKPWQMKTH FLMPFPVNYV GECIRTVPYT DPDHASLKIL ARLMTAKFLH TEIREKGGAY GGGAKLSHNG IFTLYSYRDP NTIETLQSFG KAVDWAKSGK FTQQDIDEAK LSVFSTVDAP VAPSDKGMDH FLYGLSDEMK QAHREQLFAV SHDKLLAVSD RYLGTGKSTH GLAILGPENP KIAKDPSWII Q
Genular Protein ID: 1637155346
Symbol: A0A0A0MRX9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 832
- Mass: 93696
- Checksum: AA4619827401B8B8
- Sequence:
MKGAFTDNER IFSQHLQNRL LPDHTYSVVS GGDPLCIPEL TWEQLKQFHA THYHPSNARF FTYGNFPLEQ HLKQIHEEAL SKFQKIEPST VVPAQTPWDK PREFQITCGP DSFATDPSKQ TTISVSFLLP DITDTFEAFT LSLLSSLLTS GPNSPFYKAL IESGLGTDFS PDVGYNGYTR EAYFSVGLQG IAEKDIETVR SLIDRTIDEV VEKGFEDDRI EALLHKIEIQ MKHQSTSFGL MLTSYIASCW NHDGDPVELL KLGNQLAKFR QCLQENPKFL QEKVKQYFKN NQHKLTLSMR PDDKYHEKQA QVEATKLKQK VEALSPGDRQ QIYEKGLELR SQQSKPQDAS CLPALKVSDI EPTIPVTELD VVLTAGDIPV QYCAQPTNGM VYFRAFSSLN TLPEELRPYV PLFCSVLTKL GCGLLDYREQ AQQIELKTGG MSASPHVLPD DSHMDTYEQG VLFSSLCLDR NLPDMMQLWS EIFNNPCFEE EEHFKVLVKM TAQELANGIP DSGHLYASIR AGRTLTPAGD LQETFSGMDQ VRLMKRIAEM TDIKPILRKL PRIKKHLLNG DNMRCSVNAT PQQMPQTEKA VEDFLRSIGR SKKERRPVRP HTVEKPVPSS SGGDAHVPHG SQVIRKLVME PTFKPWQMKT HFLMPFPVNY VGECIRTVPY TDPDHASLKI LARLMTAKFL HTEIREKGGA YGGGAKLSHN GIFTLYSYRD PNTIETLQSF GKAVDWAKSG KFTQQDIDEA KLSVFSTVDA PVAPSDKGMD HFLYGLSDEM KQAHREQLFA VSHDKLLAVS DRYLGTGKST HGLAILGPEN PKIAKDPSWI IQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.