P3H3 | ENSG00000110811 | NCBI 10536

Details for: P3H3

Gene ID: 10536

Symbol: P3H3

Ensembl ID: ENSG00000110811

Description: prolyl 3-hydroxylase 3

Associated with

Collagen biosynthesis and modifying enzymes
(R-HSA-1650814)
Collagen formation
(R-HSA-1474290)
Extracellular matrix organization
(R-HSA-1474244)
Catalytic complex
(GO:1902494)
Collagen biosynthetic process
(GO:0032964)
Collagen metabolic process
(GO:0032963)
Endoplasmic reticulum
(GO:0005783)
Iron ion binding
(GO:0005506)
L-ascorbic acid binding
(GO:0031418)
Negative regulation of cell population proliferation
(GO:0008285)
Peptidyl-lysine hydroxylation
(GO:0017185)
Procollagen-proline 3-dioxygenase activity
(GO:0019797)

Other Information

Proteins

P3H3_HUMAN

Genular Protein ID: 513714412

Symbol: P3H3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IVL6 Q13512 Q15740 Q66K32 Q6NX61 Q7L2T1

Database IDs:

Citations:

PubMed ID: 8723724

Title: A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13.

PubMed ID: 8723724

DOI: 10.1101/gr.6.4.314

PubMed ID: 9074930

Title: Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.

PubMed ID: 9074930

DOI: 10.1101/gr.7.3.268

PubMed ID: 15063763

Title: LEPREL1, a novel ER and Golgi resident member of the Leprecan family.

PubMed ID: 15063763

DOI: 10.1016/j.bbrc.2004.03.060

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 28115524

Title: P3h3-null and Sc65-null Mice Phenocopy the Collagen Lysine Under-hydroxylation and Cross-linking Abnormality of Ehlers-Danlos Syndrome Type VIA.

PubMed ID: 28115524

DOI: 10.1074/jbc.m116.762245

Sequence Information:

Length: 736
Mass: 81837
Checksum: 82526D30C9788369
Sequence:

MLRLLRPLLL LLLLPPPGSP EPPGLTQLSP GAPPQAPDLL YADGLRAYAA GAWAPAVALL 
REALRSQAAL GRVRLDCGAS CAADPGAALP AVLLGAPEPD SGPGPTQGSW ERQLLRAALR 
RADCLTQCAA RRLGPGGAAR LRVGSALRDA FRRREPYNYL QRAYYQLKKL DLAAAAAHTF 
FVANPMHLQM REDMAKYRRM SGVRPQSFRD LETPPHWAAY DTGLELLGRQ EAGLALPRLE 
EALQGSLAQM ESCRADCEGP EEQQGAEEEE DGAASQGGLY EAIAGHWIQV LQCRQRCVGE 
TATRPGRSFP VPDFLPNQLR RLHEAHAQVG NLSQAIENVL SVLLFYPEDE AAKRALNQYQ 
AQLGEPRPGL GPREDIQRFI LRSLGEKRQL YYAMEHLGTS FKDPDPWTPA ALIPEALREK 
LREDQEKRPW DHEPVKPKPL TYWKDVLLLE GVTLTQDSRQ LNGSERAVLD GLLTPAECGV 
LLQLAKDAAG AGARSGYRGR RSPHTPHERF EGLTVLKAAQ LARAGTVGSQ GAKLLLEVSE 
RVRTLTQAYF SPERPLHLSF THLVCRSAIE GEQEQRMDLS HPVHADNCVL DPDTGECWRE 
PPAYTYRDYS GLLYLNDDFQ GGDLFFTEPN ALTVTARVRP RCGRLVAFSS GVENPHGVWA 
VTRGRRCALA LWHTWAPEHR EQEWIEAKEL LQESQEEEEE EEEEMPSKDP SPEPPSRRHQ 
RVQDKTGRAP RVREEL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: P3H3

Associated with

Other Information

A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. PubMed ID: 8723724

Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. PubMed ID: 9074930

LEPREL1, a novel ER and Golgi resident member of the Leprecan family. PubMed ID: 15063763

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Initial characterization of the human central proteome. PubMed ID: 21269460