Gene CEBPG - ENSG00000153879 | NCBI Gene ID: 1054

Details for: CEBPG

Gene ID: 1054

Symbol: CEBPG

Ensembl ID: ENSG00000153879

Description: CCAAT enhancer binding protein gamma

Associated with

Atf4 activates genes in response to endoplasmic reticulum stress
(R-HSA-380994)
Cellular responses to stimuli
(R-HSA-8953897)
Cellular responses to stress
(R-HSA-2262752)
Cellular response to starvation
(R-HSA-9711097)
Perk regulates gene expression
(R-HSA-381042)
Response of eif2ak1 (hri) to heme deficiency
(R-HSA-9648895)
Response of eif2ak4 (gcn2) to amino acid deficiency
(R-HSA-9633012)
Unfolded protein response (upr)
(R-HSA-381119)
B cell differentiation
(GO:0030183)
Chromatin
(GO:0000785)
Dna-binding transcription activator activity, rna polymerase ii-specific
(GO:0001228)
Dna-binding transcription factor activity, rna polymerase ii-specific
(GO:0000981)
Dna-binding transcription factor binding
(GO:0140297)
Dna-templated transcription
(GO:0006351)
Dna binding
(GO:0003677)
Enucleate erythrocyte differentiation
(GO:0043353)
Identical protein binding
(GO:0042802)
Immune response
(GO:0006955)
Integrated stress response signaling
(GO:0140467)
Liver development
(GO:0001889)
Mrna metabolic process
(GO:0016071)
Natural killer cell mediated cytotoxicity
(GO:0042267)
Negative regulation of dna-binding transcription factor activity
(GO:0043433)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of dna binding
(GO:0043388)
Positive regulation of dna repair
(GO:0045739)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of type ii interferon production
(GO:0032729)
Protein binding
(GO:0005515)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Rna polymerase ii cis-regulatory region sequence-specific dna binding
(GO:0000978)
Rna polymerase ii transcription regulator complex
(GO:0090575)
Sequence-specific dna binding
(GO:0043565)
Sequence-specific double-stranded dna binding
(GO:1990837)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: colon epithelial cell (CL0011108)
Fold Change: 1.97
Marker Score: 6182
Cell Name: enterocyte (CL0000584)
Fold Change: 1.61
Marker Score: 7707
Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.46
Marker Score: 1153
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.39
Marker Score: 2054
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.35
Marker Score: 3293
Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: 1.32
Marker Score: 3279
Cell Name: stem cell (CL0000034)
Fold Change: 1.19
Marker Score: 2835
Cell Name: primordial germ cell (CL0000670)
Fold Change: 1.19
Marker Score: 1486
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.18
Marker Score: 40305
Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 1.17
Marker Score: 1254
Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 1.17
Marker Score: 397
Cell Name: PP cell (CL0000696)
Fold Change: 1.16
Marker Score: 262
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.14
Marker Score: 7303
Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 1.13
Marker Score: 9763
Cell Name: oogonial cell (CL0000024)
Fold Change: 1.13
Marker Score: 1626
Cell Name: intestine goblet cell (CL0019031)
Fold Change: 1.11
Marker Score: 1068
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 1.09
Marker Score: 8486
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.05
Marker Score: 5161.5
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.03
Marker Score: 1080.5
Cell Name: IgG memory B cell (CL0000979)
Fold Change: 1.01
Marker Score: 607
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.01
Marker Score: 1004
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.01
Marker Score: 3957
Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 1
Marker Score: 632
Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71661
Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 0.99
Marker Score: 47885
Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 0.99
Marker Score: 352
Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.99
Marker Score: 577
Cell Name: male germ cell (CL0000015)
Fold Change: 0.98
Marker Score: 283
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.98
Marker Score: 54907
Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30384
Cell Name: endothelial cell (CL0000115)
Fold Change: 0.97
Marker Score: 870
Cell Name: keratinocyte (CL0000312)
Fold Change: 0.95
Marker Score: 792
Cell Name: large pre-B-II cell (CL0000957)
Fold Change: 0.94
Marker Score: 2566
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.94
Marker Score: 2391
Cell Name: enterocyte of colon (CL1000347)
Fold Change: 0.93
Marker Score: 1439
Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 0.93
Marker Score: 351
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.92
Marker Score: 476
Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.91
Marker Score: 432
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.91
Marker Score: 1612
Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.91
Marker Score: 5189
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: 0.91
Marker Score: 1401
Cell Name: pneumocyte (CL0000322)
Fold Change: 0.91
Marker Score: 1455
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.9
Marker Score: 3459
Cell Name: abnormal cell (CL0001061)
Fold Change: 0.9
Marker Score: 2684
Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: 0.9
Marker Score: 348
Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.89
Marker Score: 255
Cell Name: alveolar macrophage (CL0000583)
Fold Change: 0.89
Marker Score: 22674
Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 0.88
Marker Score: 560
Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.88
Marker Score: 1485
Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.88
Marker Score: 263
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5280
Cell Name: endothelial cell of uterus (CL0009095)
Fold Change: 0.87
Marker Score: 1739
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.85
Marker Score: 307
Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.85
Marker Score: 205
Cell Name: vein endothelial cell (CL0002543)
Fold Change: 0.85
Marker Score: 765
Cell Name: glandular epithelial cell (CL0000150)
Fold Change: 0.83
Marker Score: 2050
Cell Name: hepatocyte (CL0000182)
Fold Change: 0.83
Marker Score: 565
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.82
Marker Score: 735
Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.82
Marker Score: 1348
Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 0.82
Marker Score: 7139
Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.82
Marker Score: 1858
Cell Name: basal cell (CL0000646)
Fold Change: 0.81
Marker Score: 1049
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.81
Marker Score: 896
Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.81
Marker Score: 2986
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.81
Marker Score: 200
Cell Name: pulmonary artery endothelial cell (CL1001568)
Fold Change: 0.8
Marker Score: 691
Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
Fold Change: 0.8
Marker Score: 1558
Cell Name: mature B cell (CL0000785)
Fold Change: 0.8
Marker Score: 585
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.79
Marker Score: 6804
Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.78
Marker Score: 599.5
Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.78
Marker Score: 357
Cell Name: microglial cell (CL0000129)
Fold Change: 0.78
Marker Score: 1423
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1264
Cell Name: transitional stage B cell (CL0000818)
Fold Change: 0.78
Marker Score: 275
Cell Name: precursor cell (CL0011115)
Fold Change: 0.77
Marker Score: 188
Cell Name: dendritic cell, human (CL0001056)
Fold Change: 0.77
Marker Score: 787
Cell Name: capillary endothelial cell (CL0002144)
Fold Change: 0.77
Marker Score: 829.5
Cell Name: cardiac mesenchymal cell (CL0000569)
Fold Change: 0.76
Marker Score: 188
Cell Name: common dendritic progenitor (CL0001029)
Fold Change: 0.76
Marker Score: 263
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.76
Marker Score: 305
Cell Name: Unknown (CL0000548)
Fold Change: 0.75
Marker Score: 548
Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.75
Marker Score: 310
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.74
Marker Score: 11621
Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 0.74
Marker Score: 1409
Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.74
Marker Score: 1505
Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
Fold Change: 0.74
Marker Score: 1881
Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.74
Marker Score: 407
Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.74
Marker Score: 472
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.74
Marker Score: 176
Cell Name: oocyte (CL0000023)
Fold Change: 0.74
Marker Score: 182
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.73
Marker Score: 4776
Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.73
Marker Score: 690
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 0.73
Marker Score: 5418
Cell Name: mesenchymal lymphangioblast (CL0005021)
Fold Change: 0.73
Marker Score: 162
Cell Name: NKp44-positive group 3 innate lymphoid cell, human (CL0001079)
Fold Change: 0.73
Marker Score: 164
Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.72
Marker Score: 7307
Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.72
Marker Score: 808.5
Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.72
Marker Score: 489
Cell Name: dendritic cell (CL0000451)
Fold Change: 0.72
Marker Score: 492
Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.72
Marker Score: 371

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**Key characteristics**: * The CEBPG gene is located on chromosome 17q21. * It is a member of the CCAAT family of transcription factors. * It is induced by the endoplasmic reticulum stress response (ERS) and by a variety of stimuli, including cytokines, hormones, and growth factors. * It binds to DNA sequences rich in GGGCGC motifs. * It is a key regulator of gene expression in a variety of physiological and pathological conditions. **Pathways and functions**: * CEBPG is a key regulator of the expression of genes involved in stress resistance, cell cycle regulation, and apoptosis. * It is involved in the regulation of hepatic glucose metabolism, inflammation, and cancer. * It is also involved in the regulation of the immune response. **Clinical significance**: * Mutations in the CEBPG gene have been linked to a number of human diseases, including liver disease, cancer, and autoimmune disorders. * CEBPG is a potential therapeutic target for these diseases. **Additional information**: * The CEBPG protein is a highly conserved protein that is found in all eukaryotes. * It is a well-characterized protein that has been extensively studied in model systems. * It is a promising target for the treatment of a variety of diseases.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

CCAAT/enhancer-binding protein gamma

Genular Protein ID: 2498218559

Symbol: CEBPG_HUMAN

Name: CCAAT/enhancer-binding protein gamma

UniProtKB Accession Codes:

P53567 B2R946 Q5U052

Database IDs:

Citations:

PubMed ID: 7665092

Title: Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter.

PubMed ID: 7665092

DOI: 10.1016/0378-1119(95)00271-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

Length: 150
Mass: 16408
Checksum: 630D1C1F92A00186
Sequence:

MSKISQQNST PGVNGISVIH TQAHASGLQQ VPQLVPAGPG GGGKAVAPSK QSKKSSPMDR 
NSDEYRQRRE RNNMAVKKSR LKSKQKAQDT LQRVNQLKEE NERLEAKIKL LTKELSVLKD 
LFLEHAHNLA DNVQSISTEN TTADGDNAGQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: CEBPG

Associated with

Cells (max top 100)

Other Information

Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter. PubMed ID: 7665092

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334