Details for: CEL
Gene ID: 1056
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: CEL
Ensembl ID: ENSG00000170835
Description: carboxyl ester lipase
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 9.38rCSI 12.47%PRS 99.35
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CSI 8.14rCSI 7.16%PRS 98.35
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CSI 5.28rCSI 5.66%PRS 99.53
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CSI 4.41rCSI 5.37%PRS 99.56
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CSI 4.01rCSI 6.17%PRS 97.56
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CSI 3.01rCSI 3.15%PRS 99.36
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CSI 2.39rCSI 6.45%PRS 99.8
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CSI 1.92rCSI 3.72%PRS 99.42
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CSI 1.74rCSI 3.86%PRS 99.27
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CSI 0.79rCSI 4.6%PRS 99.35
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
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Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 328110702
Symbol: O75612_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9774442
Title: Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase.
PubMed ID: 9774442
Sequence Information:
- Length: 612
- Mass: 66363
- Checksum: A5E9092D19390B26
- Sequence:
AKLGAVYTEG GFVEGVNKKL GLLGDSVDIF KGIPFAAPTK ALENPQPHPG WQGTLKAKNF KKRCLQATIT QDSTYGDEDC LYLNIWVPQG RKQVSRDLPV MIWIYGGAFL MGSGHGANFL NNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG NYGLRDQHMA IAWVKRNIAA FGGDPNNITL FGESAGGASV SLQTLSPYNK GLIRRAISQS GVALSPWVIQ KNPLFWAKKV AEKVGCPVGD AARMAQCLKV TDPRALTLAY KVPLAGLEYP MLHYVGFVPV IDGDFIPADP INLYANAADI DYIAGTNNMD GHIFASIDMP AINKGNKKVT EEDFYKLVSE FTITKGLRGA KTTFDVYTES WAQDPSQENK KKTVVDFETD VLFLVPTEIA LAQHRANAKS AKTYAYLFSH PSRMPVYPKW VGADHADDIQ YVFGKPFATP TGYRPQDRTV SKAMIAYWTN FAKTGDPNMG DSAVPTHWEP YTTENSGYLE ITKKMGSSSM KRSLRTNFLR YWTLTYLALP TVTDQEATPV PPTGDSEATP VPPTGDSETA PVPPTGDSGA PPVPPTGDSG APPVPPTGDS EAAPVPPTGD SKEAQMPAVI RF
Genular Protein ID: 1383753183
Symbol: B4DSX9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 521
- Mass: 55909
- Checksum: 9AA18B4E89656285
- Sequence:
MIWIYGGAFL MGSGHGANFL NNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG NYGLRDQHMA IAWVKRNIAA FGGDPNNITL FGESAGGASV SLQTLSPYNK GLIRRAISQS GVALSPWVIQ KNPLFWAKKV AEKVGCPVGD AARMAQCLKV TDPRALTLAY KVPLAGLEYP MLHYVGFVPV IDGDFIPADP INLYANAADI DYIAGTNNMD GHIFASIDMP AINKGNKKVT EEDFYKLVSE FTITKGLRGA KTTFDVYTES WAQDPSQENK KKTVVDFETD VLFLVPTEIA LAQHRANAKS AKTYAYLFSH PSRMPVYPKW VGADHADDIQ YVFGKPFATP TGYRPQDRTV SKAMIAYWTN FAKTGDPNMG DSAVPTHWEP YTTENSGYLE ITKKMGSSSM KRSLRTNFLR YWTLTYLALP TVTDQEATPV PPTGDSEATP VPPTGDSETA PVPPTGDSGA PPVPPTGDSG APPVPPTGDS GAPPVPPTGD SGAPPVPPTG DSGAPPRAAH G
Genular Protein ID: 3670956093
Symbol: Q86SR3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 722
- Mass: 76610
- Checksum: 8AA686E4CF02928B
- Sequence:
MLTMGRLQLV VLGLTCCWAV ASAAKLGAVY TEGGFVEGVN KKLGLLGDSV DIFKGIPFAA PTKALENPQP HPGWQGTLKA KNFKKRCLQA TITQDSTYGD EDCLYLNIWV PQGRKQVSRD LPVMIWIYGG AFLMGSGHGA NFLNNYLYDG EEIATRGNVI VVTFNYRVGP LGFLSTGDAN LPGNYGLRDQ HMAIAWVKRN IAAFGGDPNN ITLFGESAGG ASVSLQTLSP YNKGLIRRAI SQSGVALSPW VIQKNPLFWA KKVAEKVGCP VGDAARMAQC LKVTDPRALT LAYKVPLAGL EYPMLHYVGF VPVIDGDFIP ADPINLYANA ADIDYIAGTN NMDGHIFASI DMPAINKGNK KVTEDFYKLV SEFTITKGLR GAKTTFDVYT ESWAQDPSQE NKKKTVVDFE TDVLFLVPTE IALAQHRANA KSAKTYAYLF SHPSRMPVYP KWVGADHADD IQYVFGKPFA TPTGYRPQDR TVSKAMIAYW TNFAKTGDPN MGDSAVPTHW EPYTTENSGY LEITKKMGSS SMKRSLRTNF LRYWTLTYLA LPTVTDQEAT PVPPTGDSEA TPVPPTGDSE TAPVPPTGDS GAPPVPPTGD SGAPPVPPTG DSGAPPVPPT GDSGAPPVPP TGDSGAPPVP PTGDAGPPPV PPTGDSGAPP VPPTGDSGAP PVTPTGDSET APVPPTGDSG APPVPPTGDS EAAPVPPTDD SKEAQMPAVI RF