Details for: CEL

Gene ID: 1056

Symbol: CEL

Ensembl ID: ENSG00000170835

Description: carboxyl ester lipase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 21.6014
    Cell Significance Index: -3.3600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 18.1703
    Cell Significance Index: 2074.1200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 13.1287
    Cell Significance Index: -3.3300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 9.4479
    Cell Significance Index: 1613.2900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 6.1322
    Cell Significance Index: 196.4100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 3.8754
    Cell Significance Index: -3.7000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.9881
    Cell Significance Index: 378.3600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.4774
    Cell Significance Index: 146.1500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0936
    Cell Significance Index: 987.4100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8695
    Cell Significance Index: 94.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7794
    Cell Significance Index: 126.7700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7681
    Cell Significance Index: 46.1100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6107
    Cell Significance Index: 28.7000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.4800
    Cell Significance Index: 4.4200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4520
    Cell Significance Index: 31.2600
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.2685
    Cell Significance Index: 3.2500
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.2142
    Cell Significance Index: 2.4900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1773
    Cell Significance Index: 35.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1667
    Cell Significance Index: 8.6600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1590
    Cell Significance Index: 4.2600
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.1540
    Cell Significance Index: 1.9400
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.1535
    Cell Significance Index: 1.0800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.1371
    Cell Significance Index: 1.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1223
    Cell Significance Index: 24.5300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1111
    Cell Significance Index: 12.7300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0993
    Cell Significance Index: 2.8600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0836
    Cell Significance Index: 1.7400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0740
    Cell Significance Index: 40.4100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0737
    Cell Significance Index: 1.1100
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.0620
    Cell Significance Index: 0.8700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0599
    Cell Significance Index: 10.7900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.0531
    Cell Significance Index: 0.8800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.0497
    Cell Significance Index: 1.2400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0441
    Cell Significance Index: 1.6700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0430
    Cell Significance Index: 1.9000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0384
    Cell Significance Index: 28.1300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0336
    Cell Significance Index: 0.8400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0294
    Cell Significance Index: 3.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0290
    Cell Significance Index: 1.9500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0287
    Cell Significance Index: 10.2900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0273
    Cell Significance Index: 18.8500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0271
    Cell Significance Index: 0.3700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0263
    Cell Significance Index: 0.5600
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.0113
    Cell Significance Index: 0.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0092
    Cell Significance Index: 0.2000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0088
    Cell Significance Index: 0.2500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0023
    Cell Significance Index: 0.0800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0021
    Cell Significance Index: 0.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.0020
    Cell Significance Index: 1.1500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0014
    Cell Significance Index: 1.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0009
    Cell Significance Index: 0.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.0009
    Cell Significance Index: 0.2000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0002
    Cell Significance Index: -0.3800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0007
    Cell Significance Index: -1.3400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0011
    Cell Significance Index: -1.6200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0023
    Cell Significance Index: -1.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0023
    Cell Significance Index: -3.1300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0033
    Cell Significance Index: -0.3800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0035
    Cell Significance Index: -1.5300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0042
    Cell Significance Index: -0.1800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0048
    Cell Significance Index: -3.6400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0049
    Cell Significance Index: -3.1200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0059
    Cell Significance Index: -0.8100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0071
    Cell Significance Index: -3.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0087
    Cell Significance Index: -0.5400
  • Cell Name: PP cell (CL0000696)
    Fold Change: -0.0089
    Cell Significance Index: -0.0900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0092
    Cell Significance Index: -2.6600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0116
    Cell Significance Index: -1.6900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0135
    Cell Significance Index: -0.1400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0161
    Cell Significance Index: -2.0700
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: -0.0162
    Cell Significance Index: -0.0900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0172
    Cell Significance Index: -1.3200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0240
    Cell Significance Index: -0.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0255
    Cell Significance Index: -3.2900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0255
    Cell Significance Index: -0.6700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0269
    Cell Significance Index: -1.6500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0290
    Cell Significance Index: -1.5100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0300
    Cell Significance Index: -0.9600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0303
    Cell Significance Index: -3.1000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0316
    Cell Significance Index: -3.2900
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0320
    Cell Significance Index: -0.7400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0329
    Cell Significance Index: -3.8800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0339
    Cell Significance Index: -2.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0368
    Cell Significance Index: -2.0700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0374
    Cell Significance Index: -0.5400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0398
    Cell Significance Index: -3.1500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0413
    Cell Significance Index: -1.1300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0443
    Cell Significance Index: -2.8600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0509
    Cell Significance Index: -3.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0514
    Cell Significance Index: -3.2400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0551
    Cell Significance Index: -1.9300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0557
    Cell Significance Index: -0.9600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0586
    Cell Significance Index: -1.9200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0654
    Cell Significance Index: -0.8600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0673
    Cell Significance Index: -3.1400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0688
    Cell Significance Index: -3.6100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0796
    Cell Significance Index: -1.1400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0804
    Cell Significance Index: -2.9500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0822
    Cell Significance Index: -1.7500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0824
    Cell Significance Index: -1.7800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CEL is a member of the esterase family, specifically classified as a carboxyl ester lipase. It is a secreted enzyme, primarily produced by the exocrine pancreas, with significant expression in epithelial cells of the pancreas, pancreatic acinar cells, and intestinal epithelial cells. CEL's molecular weight ranges from 55 to 60 kDa, and it exhibits a high degree of specificity for triglyceride lipase activity. **Pathways and Functions:** CEL is involved in various signaling pathways, including: 1. **Lipid Metabolic Process:** CEL plays a crucial role in the hydrolysis of triglycerides, enabling the breakdown of dietary fats and the absorption of fatty acids. 2. **Acetylesterase Activity:** CEL's esterolytic activity is essential for the degradation of ester bonds in lipids, including triglycerides, cholesterol esters, and phospholipids. 3. **Ceramide Catabolic Process:** CEL's lipid hydrolytic activity is also involved in the breakdown of ceramides, a type of sphingolipid, which is essential for cellular signaling and membrane structure. 4. **Heparin Binding:** CEL's ability to bind heparin is significant, as it enables the enzyme to interact with heparin-binding proteins and modulate its activity. **Clinical Significance:** Dysregulation of the CEL gene has been implicated in various diseases, including: 1. **Pancreatic Insufficiency:** Impaired CEL activity can lead to pancreatic insufficiency, characterized by malabsorption of dietary fats and fatty acids. 2. **Diabetes:** Alterations in CEL expression and activity have been linked to the development of type 2 diabetes, a metabolic disorder characterized by insulin resistance and impaired glucose metabolism. 3. **Atherosclerosis:** CEL's role in lipid metabolism and its ability to modulate cholesterol esterase activity make it an important regulator of atherosclerosis, a cardiovascular disease characterized by the buildup of fatty plaques in arteries. In conclusion, the carboxyl ester lipase gene (CEL) plays a vital role in lipid metabolism, cellular signaling, and various physiological processes. Its dysregulation can lead to a range of diseases, highlighting the importance of understanding the molecular mechanisms underlying CEL's functions. Further research is necessary to elucidate the complex interactions between CEL and other genes, proteins, and signaling pathways, ultimately leading to the development of novel therapeutic strategies for diseases associated with CEL dysfunction.

Genular Protein ID: 328110702

Symbol: O75612_HUMAN

Name: N/A

UniProtKB Accession Codes:

O75612

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ESTHER 1 GO 7 Gene3D 1 InterPro 5 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 9774442

Title: Molecular cloning of the oncofetal isoform of the human pancreatic bile salt-dependent lipase.

PubMed ID: 9774442

DOI: 10.1074/jbc.273.43.28208

Sequence Information:

  • Length: 612
  • Mass: 66363
  • Checksum: A5E9092D19390B26
  • Sequence:
    • AKLGAVYTEG GFVEGVNKKL GLLGDSVDIF KGIPFAAPTK ALENPQPHPG WQGTLKAKNF 
KKRCLQATIT QDSTYGDEDC LYLNIWVPQG RKQVSRDLPV MIWIYGGAFL MGSGHGANFL 
NNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG NYGLRDQHMA IAWVKRNIAA 
FGGDPNNITL FGESAGGASV SLQTLSPYNK GLIRRAISQS GVALSPWVIQ KNPLFWAKKV 
AEKVGCPVGD AARMAQCLKV TDPRALTLAY KVPLAGLEYP MLHYVGFVPV IDGDFIPADP 
INLYANAADI DYIAGTNNMD GHIFASIDMP AINKGNKKVT EEDFYKLVSE FTITKGLRGA 
KTTFDVYTES WAQDPSQENK KKTVVDFETD VLFLVPTEIA LAQHRANAKS AKTYAYLFSH 
PSRMPVYPKW VGADHADDIQ YVFGKPFATP TGYRPQDRTV SKAMIAYWTN FAKTGDPNMG 
DSAVPTHWEP YTTENSGYLE ITKKMGSSSM KRSLRTNFLR YWTLTYLALP TVTDQEATPV 
PPTGDSEATP VPPTGDSETA PVPPTGDSGA PPVPPTGDSG APPVPPTGDS EAAPVPPTGD 
SKEAQMPAVI RF

Genular Protein ID: 1383753183

Symbol: B4DSX9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DSX9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ESTHER 1 GO 1 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SUPFAM 1

Sequence Information:

  • Length: 521
  • Mass: 55909
  • Checksum: 9AA18B4E89656285
  • Sequence:
    • MIWIYGGAFL MGSGHGANFL NNYLYDGEEI ATRGNVIVVT FNYRVGPLGF LSTGDANLPG 
NYGLRDQHMA IAWVKRNIAA FGGDPNNITL FGESAGGASV SLQTLSPYNK GLIRRAISQS 
GVALSPWVIQ KNPLFWAKKV AEKVGCPVGD AARMAQCLKV TDPRALTLAY KVPLAGLEYP 
MLHYVGFVPV IDGDFIPADP INLYANAADI DYIAGTNNMD GHIFASIDMP AINKGNKKVT 
EEDFYKLVSE FTITKGLRGA KTTFDVYTES WAQDPSQENK KKTVVDFETD VLFLVPTEIA 
LAQHRANAKS AKTYAYLFSH PSRMPVYPKW VGADHADDIQ YVFGKPFATP TGYRPQDRTV 
SKAMIAYWTN FAKTGDPNMG DSAVPTHWEP YTTENSGYLE ITKKMGSSSM KRSLRTNFLR 
YWTLTYLALP TVTDQEATPV PPTGDSEATP VPPTGDSETA PVPPTGDSGA PPVPPTGDSG 
APPVPPTGDS GAPPVPPTGD SGAPPVPPTG DSGAPPRAAH G

Genular Protein ID: 3670956093

Symbol: Q86SR3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q86SR3

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 ESTHER 1 GO 1 Gene3D 1 InterPro 5 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 722
  • Mass: 76610
  • Checksum: 8AA686E4CF02928B
  • Sequence:
    • MLTMGRLQLV VLGLTCCWAV ASAAKLGAVY TEGGFVEGVN KKLGLLGDSV DIFKGIPFAA 
PTKALENPQP HPGWQGTLKA KNFKKRCLQA TITQDSTYGD EDCLYLNIWV PQGRKQVSRD 
LPVMIWIYGG AFLMGSGHGA NFLNNYLYDG EEIATRGNVI VVTFNYRVGP LGFLSTGDAN 
LPGNYGLRDQ HMAIAWVKRN IAAFGGDPNN ITLFGESAGG ASVSLQTLSP YNKGLIRRAI 
SQSGVALSPW VIQKNPLFWA KKVAEKVGCP VGDAARMAQC LKVTDPRALT LAYKVPLAGL 
EYPMLHYVGF VPVIDGDFIP ADPINLYANA ADIDYIAGTN NMDGHIFASI DMPAINKGNK 
KVTEDFYKLV SEFTITKGLR GAKTTFDVYT ESWAQDPSQE NKKKTVVDFE TDVLFLVPTE 
IALAQHRANA KSAKTYAYLF SHPSRMPVYP KWVGADHADD IQYVFGKPFA TPTGYRPQDR 
TVSKAMIAYW TNFAKTGDPN MGDSAVPTHW EPYTTENSGY LEITKKMGSS SMKRSLRTNF 
LRYWTLTYLA LPTVTDQEAT PVPPTGDSEA TPVPPTGDSE TAPVPPTGDS GAPPVPPTGD 
SGAPPVPPTG DSGAPPVPPT GDSGAPPVPP TGDSGAPPVP PTGDAGPPPV PPTGDSGAPP 
VPPTGDSGAP PVTPTGDSET APVPPTGDSG APPVPPTGDS EAAPVPPTDD SKEAQMPAVI 
RF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.