OLFM4 | ENSG00000102837 | NCBI 10562

Details for: OLFM4

Gene ID: 10562

Symbol: OLFM4

Ensembl ID: ENSG00000102837

Description: olfactomedin 4

Associated with

Immune system
(R-HSA-168256)
Innate immune system
(R-HSA-168249)
Neutrophil degranulation
(R-HSA-6798695)
Azurophil granule
(GO:0042582)
Cadherin binding
(GO:0045296)
Cell adhesion
(GO:0007155)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Intercellular bridge
(GO:0045171)
Mitochondrion
(GO:0005739)
Nucleoplasm
(GO:0005654)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of substrate adhesion-dependent cell spreading
(GO:1900026)
Protein-containing complex
(GO:0032991)
Protein binding
(GO:0005515)
Secretory granule
(GO:0030141)
Signal transduction
(GO:0007165)
Specific granule
(GO:0042581)
Specific granule lumen
(GO:0035580)
Structural molecule activity
(GO:0005198)
Tertiary granule lumen
(GO:1904724)

Other Information

Proteins

Olfactomedin-4

Genular Protein ID: 1280020859

Symbol: OLFM4_HUMAN

Name: Olfactomedin-4

UniProtKB Accession Codes:

Q6UX06 O95362 Q5VWG0 Q86T22

Database IDs:

Citations:

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11867215

Title: Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development.

PubMed ID: 11867215

DOI: 10.1016/s0378-1119(01)00763-6

PubMed ID: 15059901

Title: GW112, a novel antiapoptotic protein that promotes tumor growth.

PubMed ID: 15059901

DOI: 10.1158/0008-5472.can-03-3443

PubMed ID: 16566923

Title: The glycoprotein hGC-1 binds to cadherin and lectins.

PubMed ID: 16566923

DOI: 10.1016/j.yexcr.2006.02.011

PubMed ID: 17270022

Title: Olfactomedin 4 promotes S-phase transition in proliferation of pancreatic cancer cells.

PubMed ID: 17270022

DOI: 10.1111/j.1349-7006.2007.00397.x

PubMed ID: 20724538

Title: Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.

PubMed ID: 20724538

DOI: 10.1182/blood-2009-10-246439

Sequence Information:

Length: 510
Mass: 57280
Checksum: ACF03365D2164900
Sequence:

MRPGLSFLLA LLFFLGQAAG DLGDVGPPIP SPGFSSFPGV DSSSSFSSSS RSGSSSSRSL 
GSGGSVSQLF SNFTGSVDDR GTCQCSVSLP DTTFPVDRVE RLEFTAHVLS QKFEKELSKV 
REYVQLISVY EKKLLNLTVR IDIMEKDTIS YTELDFELIK VEVKEMEKLV IQLKESFGGS 
SEIVDQLEVE IRNMTLLVEK LETLDKNNVL AIRREIVALK TKLKECEASK DQNTPVVHPP 
PTPGSCGHGG VVNISKPSVV QLNWRGFSYL YGAWGRDYSP QHPNKGLYWV APLNTDGRLL 
EYYRLYNTLD DLLLYINARE LRITYGQGSG TAVYNNNMYV NMYNTGNIAR VNLTTNTIAV 
TQTLPNAAYN NRFSYANVAW QDIDFAVDEN GLWVIYSTEA STGNMVISKL NDTTLQVLNT 
WYTKQYKPSA SNAFMVCGVL YATRTMNTRT EEIFYYYDTN TGKEGKLDIV MHKMQEKVQS 
INYNPFDQKL YVYNDGYLLN YDLSVLQKPQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: OLFM4

Associated with

Other Information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The DNA sequence and analysis of human chromosome 13. PubMed ID: 15057823

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification and characterization of a novel member of olfactomedin-related protein family, hGC-1, expressed during myeloid lineage development. PubMed ID: 11867215

GW112, a novel antiapoptotic protein that promotes tumor growth. PubMed ID: 15059901

The glycoprotein hGC-1 binds to cadherin and lectins. PubMed ID: 16566923

Olfactomedin 4 promotes S-phase transition in proliferation of pancreatic cancer cells. PubMed ID: 17270022

Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. PubMed ID: 20724538