Details for: SIVA1

Gene ID: 10572

Symbol: SIVA1

Ensembl ID: ENSG00000184990

Description: SIVA1 apoptosis inducing factor

Associated with

Other Information

Genular Protein ID: 343621278

Symbol: SIVA_HUMAN

Name: Apoptosis regulatory protein Siva

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9177220

Title: CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein.

PubMed ID: 9177220

DOI: 10.1073/pnas.94.12.6346

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10756043

Title: Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva.

PubMed ID: 10756043

DOI: 10.1128/jvi.74.9.4284-4290.2000

PubMed ID: 11278261

Title: The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress.

PubMed ID: 11278261

DOI: 10.1074/jbc.c100050200

PubMed ID: 11601913

Title: The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva.

PubMed ID: 11601913

DOI: 10.1006/viro.2001.1082

PubMed ID: 12011449

Title: Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis.

PubMed ID: 12011449

DOI: 10.1073/pnas.102182299

PubMed ID: 14739602

Title: The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis.

PubMed ID: 14739602

DOI: 10.1023/b:appt.0000012125.01799.4c

PubMed ID: 15034012

Title: Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway.

PubMed ID: 15034012

DOI: 10.4049/jimmunol.172.7.4008

PubMed ID: 15958577

Title: Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2.

PubMed ID: 15958577

DOI: 10.1158/0008-5472.can-04-3270

PubMed ID: 16683188

Title: The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22.

PubMed ID: 16683188

DOI: 10.1007/s11010-005-9082-6

PubMed ID: 16491128

Title: Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD).

PubMed ID: 16491128

DOI: 10.1038/sj.onc.1209381

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 175
  • Mass: 18695
  • Checksum: DB62B7DF4E6B39B3
  • Sequence:
  • MPKRSCPFAD VAPLQLKVRV SQRELSRGVC AERYSQEVFE KTKRLLFLGA QAYLDHVWDE 
    GCAVVHLPES PKPGPTGAPR AARGQMLIGP DGRLIRSLGQ ASEADPSGVA SIACSSCVRA 
    VDGKAVCGQC ERALCGQCVR TCWGCGSVAC TLCGLVDCSD MYEKVLCTSC AMFET

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.