CCT7 | ENSG00000135624 | NCBI 10574

Details for: CCT7

Gene ID: 10574

Symbol: CCT7

Ensembl ID: ENSG00000135624

Description: chaperonin containing TCP1 subunit 7

Associated with

Association of tric/cct with target proteins during biosynthesis
(R-HSA-390471)
Chaperonin-mediated protein folding
(R-HSA-390466)
Cooperation of pdcl (phlp1) and tric/cct in g-protein beta folding
(R-HSA-6814122)
Cooperation of prefoldin and tric/cct in actin and tubulin folding
(R-HSA-389958)
Folding of actin by cct/tric
(R-HSA-390450)
Formation of tubulin folding intermediates by cct/tric
(R-HSA-389960)
Metabolism of proteins
(R-HSA-392499)
Prefoldin mediated transfer of substrate to cct/tric
(R-HSA-389957)
Rhobtb1 gtpase cycle
(R-HSA-9013422)
Rhobtb2 gtpase cycle
(R-HSA-9013418)
Rhobtb gtpase cycle
(R-HSA-9706574)
Rho gtpase cycle
(R-HSA-9012999)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Atp-dependent protein folding chaperone
(GO:0140662)
Atp binding
(GO:0005524)
Atp hydrolysis activity
(GO:0016887)
Binding of sperm to zona pellucida
(GO:0007339)
Cell body
(GO:0044297)
Chaperone-mediated protein folding
(GO:0061077)
Chaperonin-containing t-complex
(GO:0005832)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Extracellular exosome
(GO:0070062)
Microtubule
(GO:0005874)
Positive regulation of establishment of protein localization to telomere
(GO:1904851)
Positive regulation of protein localization to cajal body
(GO:1904871)
Positive regulation of telomerase rna localization to cajal body
(GO:1904874)
Positive regulation of telomere maintenance via telomerase
(GO:0032212)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Protein folding chaperone
(GO:0044183)
Protein stabilization
(GO:0050821)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

T-complex protein 1 subunit eta

Genular Protein ID: 1593758706

Symbol: TCPH_HUMAN

Name: T-complex protein 1 subunit eta

UniProtKB Accession Codes:

Q99832 A8K7E6 A8MWI8 B7WNW9 B7Z4T9 B7Z4Z7 O14871 Q6FI26

Database IDs:

Citations:

PubMed ID: 9819444

Title: Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT.

PubMed ID: 9819444

DOI: 10.1128/mcb.18.12.7584

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14532270

Title: A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.

PubMed ID: 14532270

DOI: 10.1074/jbc.m309655200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25467444

Title: Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1.

PubMed ID: 25467444

DOI: 10.1016/j.cell.2014.10.059

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 33144677

Title: Dlec1 is required for spermatogenesis and male fertility in mice.

PubMed ID: 33144677

DOI: 10.1038/s41598-020-75957-y

Sequence Information:

Length: 543
Mass: 59367
Checksum: 9F1E33FA80E6238E
Sequence:

MMPTPVILLK EGTDSSQGIP QLVSNISACQ VIAEAVRTTL GPRGMDKLIV DGRGKATISN 
DGATILKLLD VVHPAAKTLV DIAKSQDAEV GDGTTSVTLL AAEFLKQVKP YVEEGLHPQI 
IIRAFRTATQ LAVNKIKEIA VTVKKADKVE QRKLLEKCAM TALSSKLISQ QKAFFAKMVV 
DAVMMLDDLL QLKMIGIKKV QGGALEDSQL VAGVAFKKTF SYAGFEMQPK KYHNPKIALL 
NVELELKAEK DNAEIRVHTV EDYQAIVDAE WNILYDKLEK IHHSGAKVVL SKLPIGDVAT 
QYFADRDMFC AGRVPEEDLK RTMMACGGSI QTSVNALSAD VLGRCQVFEE TQIGGERYNF 
FTGCPKAKTC TFILRGGAEQ FMEETERSLH DAIMIVRRAI KNDSVVAGGG AIEMELSKYL 
RDYSRTIPGK QQLLIGAYAK ALEIIPRQLC DNAGFDATNI LNKLRARHAQ GGTWYGVDIN 
NEDIADNFEA FVWEPAMVRI NALTAASEAA CLIVSVDETI KNPRSTVDAP TAAGRGRGRG 
RPH

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: CCT7

Associated with

Other Information

Maturation of human cyclin E requires the function of eukaryotic chaperonin CCT. PubMed ID: 9819444

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. PubMed ID: 14532270

Proteomic characterization of the human centrosome by protein correlation profiling. PubMed ID: 14654843

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Initial characterization of the human central proteome. PubMed ID: 21269460

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. PubMed ID: 22223895

N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. PubMed ID: 22814378

Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. PubMed ID: 25467444

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. PubMed ID: 24129315

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. PubMed ID: 28112733

Dlec1 is required for spermatogenesis and male fertility in mice. PubMed ID: 33144677