Details for: GNLY

Gene ID: 10578

Symbol: GNLY

Ensembl ID: ENSG00000115523

Description: granulysin

Associated with

Other Information

Genular Protein ID: 73265538

Symbol: GNLY_HUMAN

Name: Granulysin

UniProtKB Accession Codes:

P22749 P09325 Q6GU08

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 5 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 2434598

Title: The isolation and sequence of a novel gene from a human functional T cell line.

PubMed ID: 2434598

DOI: 10.1084/jem.165.3.601

PubMed ID: 2212946

Title: A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein.

PubMed ID: 2212946

DOI: 10.1084/jem.172.4.1159

PubMed ID: 8423048

Title: Genomic structure of NKG5, a human NK and T cell-specific activation gene.

PubMed ID: 8423048

DOI: 10.1007/bf00216832

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10644038

Title: Granulysin: a novel antimicrobial peptide of cytolytic T lymphocytes and natural killer cells.

PubMed ID: 10644038

DOI: 10.1016/s0006-2952(99)00177-x

PubMed ID: 9756476

Title: An antimicrobial activity of cytolytic T cells mediated by granulysin.

PubMed ID: 9756476

DOI: 10.1126/science.282.5386.121

PubMed ID: 10449094

Title: Biosynthesis of granulysin, a novel cytolytic molecule.

PubMed ID: 10449094

DOI: 10.1016/s0161-5890(99)00063-2

PubMed ID: 12488100

Title: Granulysin crystal structure and a structure-derived lytic mechanism.

PubMed ID: 12488100

DOI: 10.1016/s0022-2836(02)01234-2

Sequence Information:

  • Length: 145
  • Mass: 16374
  • Checksum: CEC5432FFBDBA1F4
  • Sequence:
    • MATWALLLLA AMLLGNPGLV FSRLSPEYYD LARAHLRDEE KSCPCLAQEG PQGDLLTKTQ 
ELGRDYRTCL TIVQKLKKMV DKPTQRSVSN AATRVCRTGR SRWRDVCRNF MRRYQSRVTQ 
GLVAGETAQQ ICEDLRLCIP STGPL

Genular Protein ID: 2038764857

Symbol: B4E3H9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E3H9

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 172
  • Mass: 19266
  • Checksum: D3B523F7363C620F
  • Sequence:
    • MATWALLLLA AMLLGNPGLE VSVSPKGKNT SGRESGFGWA IWMEGLVFSR LSPEYYDLAR 
AHLRDEEKSC PCLAQEGPQG DLLTKTQELG RDYRTCLTIV QKLKKMVDKP TQRSVSNAAT 
RVCRTGRSRW RDVCRNFMRR YQSRVTQGLV AGETAQQICE DLRLCIPSTG PL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.