Details for: SORBS1

Gene ID: 10580

Symbol: SORBS1

Ensembl ID: ENSG00000095637

Description: sorbin and SH3 domain containing 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 6.26
    Marker Score: 4,117
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 5.33
    Marker Score: 119,074
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 5
    Marker Score: 6,234
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 4.39
    Marker Score: 1,604
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.75
    Marker Score: 8,242
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 3.75
    Marker Score: 13,334
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.73
    Marker Score: 9,341
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 3.7
    Marker Score: 3,036
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.66
    Marker Score: 123,470
  • Cell Name: fat cell (CL0000136)
    Fold Change: 3.53
    Marker Score: 1,972
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 3.52
    Marker Score: 1,908
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.27
    Marker Score: 69,784
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.16
    Marker Score: 14,633
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 3
    Marker Score: 1,794
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.93
    Marker Score: 15,754
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.92
    Marker Score: 922
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.84
    Marker Score: 5,469
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.79
    Marker Score: 884
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.77
    Marker Score: 11,604
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.76
    Marker Score: 54,827
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.73
    Marker Score: 20,961
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 2.69
    Marker Score: 14,138
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.67
    Marker Score: 6,273
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.66
    Marker Score: 39,834
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.63
    Marker Score: 99,771
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.62
    Marker Score: 2,274
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 2.57
    Marker Score: 1,490
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.56
    Marker Score: 1,267
  • Cell Name: granule cell (CL0000120)
    Fold Change: 2.55
    Marker Score: 19,226
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.54
    Marker Score: 10,519
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.51
    Marker Score: 1,469
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.51
    Marker Score: 1,052
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.47
    Marker Score: 4,154
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.47
    Marker Score: 2,841
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.42
    Marker Score: 89,394
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.41
    Marker Score: 2,657
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.36
    Marker Score: 1,377
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.35
    Marker Score: 7,696
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 2.32
    Marker Score: 7,769
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.24
    Marker Score: 8,676
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.17
    Marker Score: 2,073
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.15
    Marker Score: 1,032
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.13
    Marker Score: 4,888
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 2.13
    Marker Score: 666
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 2.12
    Marker Score: 799
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.12
    Marker Score: 814
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.11
    Marker Score: 6,019
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.09
    Marker Score: 3,031
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.08
    Marker Score: 19,586
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.05
    Marker Score: 126,042
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 2.03
    Marker Score: 2,173
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.96
    Marker Score: 7,972
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.91
    Marker Score: 18,192
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 1.87
    Marker Score: 2,437
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.87
    Marker Score: 16,048
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.86
    Marker Score: 509
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.83
    Marker Score: 18,915
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.82
    Marker Score: 1,616
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 1.75
    Marker Score: 662
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.65
    Marker Score: 2,542
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.64
    Marker Score: 426
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.62
    Marker Score: 10,419
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.61
    Marker Score: 8,641
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.6
    Marker Score: 899
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.6
    Marker Score: 1,931
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.57
    Marker Score: 400
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.57
    Marker Score: 3,690
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.54
    Marker Score: 2,066
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.52
    Marker Score: 6,552
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.52
    Marker Score: 399
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 168,043
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.4
    Marker Score: 740
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 1.4
    Marker Score: 920
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.39
    Marker Score: 22,307
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.37
    Marker Score: 21,434
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.36
    Marker Score: 2,765
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.35
    Marker Score: 1,673
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 1.34
    Marker Score: 1,666
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.3
    Marker Score: 1,826
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.28
    Marker Score: 2,232
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.21
    Marker Score: 354
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.17
    Marker Score: 767
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.16
    Marker Score: 563
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.1
    Marker Score: 410
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.08
    Marker Score: 687
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.04
    Marker Score: 4,355
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.03
    Marker Score: 6,166
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.02
    Marker Score: 783
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.01
    Marker Score: 413
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 1.01
    Marker Score: 286
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 1.01
    Marker Score: 306
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 1
    Marker Score: 477
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1
    Marker Score: 1,877
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,771
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47,997
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.99
    Marker Score: 272
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.99
    Marker Score: 13,114
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,405
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 501
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.97
    Marker Score: 313

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular localization:** SORBS1 is predominantly localized to the plasma membrane, where it interacts with various signaling proteins and receptors. 2. **Domain structure:** The protein contains a sorbin domain, a SH3 domain, and an SH2 domain, which confer its ability to interact with multiple signaling molecules. 3. **Expression pattern:** SORBS1 is highly expressed in mature astrocytes, cardiac myocytes, neurons, and muscle fibers, suggesting its importance in maintaining tissue homeostasis. 4. **Protein interactions:** SORBS1 interacts with a wide range of proteins, including adhesion molecules, signaling receptors, and metabolic enzymes, highlighting its central role in regulating cellular processes. **Pathways and Functions:** 1. **Cell adhesion:** SORBS1 regulates cell adhesion by interacting with adhesion molecules, such as integrins and cadherins, and modulating the formation of focal adhesions and stress fibers. 2. **Signaling:** SORBS1 acts as a signaling adaptor protein, interacting with insulin receptors, growth factor receptors, and other signaling molecules to regulate cellular responses to various stimuli. 3. **Metabolic regulation:** SORBS1 regulates metabolic processes, including glucose import, glycogen biosynthesis, and lipid biosynthesis, by interacting with metabolic enzymes and signaling molecules. 4. **Cytoskeletal organization:** SORBS1 plays a role in regulating cytoskeletal organization by interacting with cytoskeletal proteins and modulating the formation of stress fibers and focal adhesions. **Clinical Significance:** 1. **Cancer:** Dysregulation of SORBS1 has been implicated in various cancers, including breast, lung, and colon cancer, where it contributes to tumor progression and metastasis. 2. **Cardiovascular disorders:** SORBS1 plays a role in regulating cardiac function and has been implicated in heart failure, hypertension, and atherosclerosis. 3. **Metabolic syndromes:** SORBS1 regulates metabolic processes, including glucose and lipid metabolism, and its dysregulation has been implicated in metabolic syndromes, such as insulin resistance and type 2 diabetes. 4. **Neurological disorders:** SORBS1 has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and stroke, where it contributes to cellular damage and death. In conclusion, SORBS1 is a critical regulator of cellular adhesion, signaling, and metabolic processes, and its dysregulation has been implicated in various diseases. Further studies are needed to fully elucidate the mechanisms by which SORBS1 regulates cellular processes and to explore its therapeutic potential.

Genular Protein ID: 3108318657

Symbol: SRBS1_HUMAN

Name: Sorbin and SH3 domain-containing protein 1

UniProtKB Accession Codes:

Q9BX66 A0AED4 A6NEK3 A6NID8 A6NJS4 A7MD40 D3DR42 O43857 Q5T923 Q5T924 Q5T927 Q5T928 Q5T929 Q5T930 Q5T931 Q5T932 Q7LBE5 Q8IVK0 Q8IVQ4 Q96KF3 Q96KF4 Q9BX64 Q9BX65 Q9P2Q0 Q9UFT2 Q9UHN7 Q9Y338

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 9 CDD 3 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 25 EPD 1 Ensembl 12 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 16 PDBsum 11 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 12 Pumba 1 RNAct 1 Reactome 1 RefSeq 13 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11374898

Title: Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B.

PubMed ID: 11374898

DOI: 10.1006/geno.2001.6541

PubMed ID: 11371513

Title: Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions.

PubMed ID: 11371513

DOI: 10.1093/hmg/10.11.1201

PubMed ID: 11532984

Title: Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes.

PubMed ID: 11532984

DOI: 10.1093/hmg/10.17.1753

PubMed ID: 12504111

Title: The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2.

PubMed ID: 12504111

DOI: 10.1016/s0006-291x(02)02894-2

PubMed ID: 17462669

Title: Paxillin and ponsin interact in nascent costameres of muscle cells.

PubMed ID: 17462669

DOI: 10.1016/j.jmb.2007.03.050

PubMed ID: 10718198

Title: Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10718198

DOI: 10.1093/dnares/7.1.65

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17784760

Title: Second SH3 domain of ponsin solved from powder diffraction.

PubMed ID: 17784760

DOI: 10.1021/ja073846c

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1292
  • Mass: 142513
  • Checksum: 70DA4169B6D82F06
  • Sequence:
    • MSSECDGGSK AVMNGLAPGS NGQDKATADP LRARSISAVK IIPVKTVKNA SGLVLPTDMD 
LTKICTGKGA VTLRASSSYR ETPSSSPASP QETRQHESKP GLEPEPSSAD EWRLSSSADA 
NGNAQPSSLA AKGYRSVHPN LPSDKSQDAT SSSAAQPEVI VVPLYLVNTD RGQEGTARPP 
TPLGPLGCVP TIPATASAAS PLTFPTLDDF IPPHLQRWPH HSQPARASGS FAPISQTPPS 
FSPPPPLVPP APEDLRRVSE PDLTGAVSST DSSPLLNEVS SSLIGTDSQA FPSVSKPSSA 
YPSTTIVNPT IVLLQHNREQ QKRLSSLSDP VSERRVGEQD SAPTQEKPTS PGKAIEKRAK 
DDSRRVVKST QDLSDVSMDE VGIPLRNTER SKDWYKTMFK QIHKLNRDTP EENPYFPTYK 
FPELPEIQQT SEEDNPYTPT YQFPASTPSP KSEDDDSDLY SPRYSFSEDT KSPLSVPRSK 
SEMSYIDGEK VVKRSATLPL PARSSSLKSS SERNDWEPPD KKVDTRKYRA EPKSIYEYQP 
GKSSVLTNEK MSRDISPEEI DLKNEPWYKF FSELEFGKPP PKKIWDYTPG DCSILPREDR 
KTNLDKDLSL CQTELEADLE KMETLNKAPS ANVPQSSAIS PTPEISSETP GYIYSSNFHA 
VKRESDGAPG DLTSLENERQ IYKSVLEGGD IPLQGLSGLK RPSSSASTKD SESPRHFIPA 
DYLESTEEFI RRRHDDKEKL LADQRRLKRE QEEADIAARR HTGVIPTHHQ FITNERFGDL 
LNIDDTAKRK SGSEMRPARA KFDFKAQTLK ELPLQKGDIV YIYKQIDQNW YEGEHHGRVG 
IFPRTYIELL PPAEKAQPKK LTPVQVLEYG EAIAKFNFNG DTQVEMSFRK GERITLLRQV 
DENWYEGRIP GTSRQGIFPI TYVDVIKRPL VKNPVDYMDL PFSSSPSRSA TASPQFSSHS 
KLITPAPSSL PHSRRALSPE MHAVTSEWIS LTVGVPGRRS LALTPPLPPL PEASIYNTDH 
LALSPRASPS LSLSLPHLSW SDRPTPRSVA SPLALPSPHK TYSLAPTSQA SLHMNGDGGV 
HTPSSGIHQD SFLQLPLGSS DSVISQLSDA FSSQSKRQPW REESGQYERK AERGAGERGP 
GGPKISKKSC LKPSDVVRCL STEQRLSDLN TPEESRPGKP LGSAFPGSEA EQTERHRGGE 
QAGRKAARRG GSQQPQAQQR RVTPDRSQTS QDLFSYQALY SYIPQNDDEL ELRDGDIVDV 
MEKCDDGWFV GTSRRTKQFG TFPGNYVKPL YL

Genular Protein ID: 3792016059

Symbol: B4DTX5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DTX5

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 6 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 2 SAM 1 SMART 2 SUPFAM 1

Sequence Information:

  • Length: 749
  • Mass: 83913
  • Checksum: E197FCEDF54D6C83
  • Sequence:
    • MSSECDGGSK AVMNGLAPGS NGQDKDMDPT KICTGKGAVT LRASSSYRET PSSSPASPQE 
TRQHESKPGL EPEPSSADEW RLSSSADANG NAQPSSLAAK GYRSVHPNLP SDKSQDSSPL 
LNEVSSSLIG TDSQAFPSVS KPSSAYPSTT IVNPTIVLLQ HNREQQKRLS SLSDPVSERR 
VGEQDSAPTQ EKPTSPGKAI EKRAKDDSRR VVKSTQDLSD VSMDEVGIPL RNTERSKDWY 
KTMFKQIHKL NRDDDSDLYS PRYSFSEDTK SPLSVPRSKS EMSYIDGEKV VKRSATLPLP 
ARSSSLKSSS ERNDWEPPDK KVDTRKYRAE PKSIYEYQPG KSSVLTNEKM SSAISPTPEI 
SSETPGYIYS SNFHAVKRES DGAPGDLTSL ENERQIYKSV LEGGDIPLQG LSGLKRPSSS 
ASTKDSESPR HFIPADYLES TEEFIRRRHD DKEKLLADQR RLKREQEEAD IAARRHTGVI 
PTHHQFITNE RFGDLLNIDD TAKRKSGSEM RPARAKFDFK AQTLKELPLQ KGDIVYIYKQ 
IDQNWYEGEH HGRVGIFPRT YIELLPPAEK AQPKKLTPVQ VLEYGEAIAK FNFNGDTQVE 
MSFRKGERIT LLRQVDENWY EGRIPGTSRQ GIFPITYVDV IKRPLVKNPV DYMDLPFSSS 
PSRSATASPQ QPQAQQRRVT PDRSQTSQDL FSYQALYSYI PQNDDELELR DGDIVDVMEK 
CDDGWFVGTS RRTKQFGTFP GNYVKPLYL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.