Details for: IFITM2

Gene ID: 10581

Symbol: IFITM2

Ensembl ID: ENSG00000185201

Description: interferon induced transmembrane protein 2

Associated with

Other Information

Genular Protein ID: 2341946148

Symbol: IFM2_HUMAN

Name: Dispanin subfamily A member 2c

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1906403

Title: Molecular analysis of a human interferon-inducible gene family.

PubMed ID: 1906403

DOI: 10.1111/j.1432-1033.1991.tb16139.x

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 20064371

Title: The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus.

PubMed ID: 20064371

DOI: 10.1016/j.cell.2009.12.017

PubMed ID: 19544527

Title: The human 1-8D gene (IFITM2) is a novel p53 independent pro-apoptotic gene.

PubMed ID: 19544527

DOI: 10.1002/ijc.24669

PubMed ID: 20534863

Title: Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections.

PubMed ID: 20534863

DOI: 10.1128/jvi.02199-09

PubMed ID: 20943977

Title: Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.

PubMed ID: 20943977

DOI: 10.1128/jvi.01328-10

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21166591

Title: The small interferon-induced transmembrane genes and proteins.

PubMed ID: 21166591

DOI: 10.1089/jir.2010.0112

PubMed ID: 21177806

Title: The IFITM proteins inhibit HIV-1 infection.

PubMed ID: 21177806

DOI: 10.1128/jvi.01531-10

PubMed ID: 21253575

Title: Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus.

PubMed ID: 21253575

DOI: 10.1371/journal.ppat.1001258

PubMed ID: 22479637

Title: IFITM proteins restrict antibody-dependent enhancement of dengue virus infection.

PubMed ID: 22479637

DOI: 10.1371/journal.pone.0034508

PubMed ID: 22363774

Title: The dispanins: a novel gene family of ancient origin that contains 14 human members.

PubMed ID: 22363774

DOI: 10.1371/journal.pone.0031961

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26354436

Title: The Interferon-induced Transmembrane Proteins, IFITM1, IFITM2, and IFITM3 Inhibit Hepatitis C Virus Entry.

PubMed ID: 26354436

DOI: 10.1074/jbc.m115.657346

PubMed ID: 33239446

Title: Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion.

PubMed ID: 33239446

DOI: 10.1073/pnas.2012197117

PubMed ID: 33270927

Title: Opposing activities of IFITM proteins in SARS-CoV-2 infection.

PubMed ID: 33270927

DOI: 10.15252/embj.2020106501

PubMed ID: 33563656

Title: The polybasic cleavage site in the SARS-CoV-2 spike modulates viral sensitivity to Type I interferon and IFITM2.

PubMed ID: 33563656

DOI: 10.1128/jvi.02422-20

Sequence Information:

  • Length: 132
  • Mass: 14632
  • Checksum: 232A32D109EEBF5D
  • Sequence:
  • MNHIVQTFSP VNSGQPPNYE MLKEEQEVAM LGVPHNPAPP MSTVIHIRSE TSVPDHVVWS 
    LFNTLFMNTC CLGFIAFAYS VKSRDRKMVG DVTGAQAYAS TAKCLNIWAL ILGIFMTILL 
    IIIPVLVVQA QR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.