Details for: POMT1

Gene ID: 10585

Symbol: POMT1

Ensembl ID: ENSG00000130714

Description: protein O-mannosyltransferase 1

Associated with

Other Information

Genular Protein ID: 838941427

Symbol: POMT1_HUMAN

Name: Protein O-mannosyl-transferase 1

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10366449

Title: Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1.

PubMed ID: 10366449

DOI: 10.1006/geno.1999.5819

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12369018

Title: Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome.

PubMed ID: 12369018

DOI: 10.1086/342975

PubMed ID: 14699049

Title: Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity.

PubMed ID: 14699049

DOI: 10.1073/pnas.0307228101

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 28512129

Title: Mammalian O-mannosylation of cadherins and plexins is independent of protein O-mannosyltransferases 1 and 2.

PubMed ID: 28512129

DOI: 10.1074/jbc.m117.794487

PubMed ID: 15037715

Title: POMT1 mutation results in defective glycosylation and loss of laminin-binding activity in alpha-DG.

PubMed ID: 15037715

DOI: 10.1212/01.wnl.0000115386.28769.65

PubMed ID: 15637732

Title: Mutations in POMT1 are found in a minority of patients with Walker-Warburg syndrome.

PubMed ID: 15637732

DOI: 10.1002/ajmg.a.30487

PubMed ID: 15792865

Title: An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 gene.

PubMed ID: 15792865

DOI: 10.1016/j.nmd.2005.01.013

PubMed ID: 16575835

Title: The expanding phenotype of POMT1 mutations: from Walker-Warburg syndrome to congenital muscular dystrophy, microcephaly, and mental retardation.

PubMed ID: 16575835

DOI: 10.1002/humu.20313

PubMed ID: 16717220

Title: Expanding the clinical spectrum of POMT1 phenotype.

PubMed ID: 16717220

DOI: 10.1212/01.wnl.0000216145.66476.36

PubMed ID: 19299310

Title: Congenital muscular dystrophies with defective glycosylation of dystroglycan: a population study.

PubMed ID: 19299310

DOI: 10.1212/01.wnl.0000346518.68110.60

Sequence Information:

  • Length: 747
  • Mass: 84881
  • Checksum: 6E1D26C87FF5D9C5
  • Sequence:
  • MWGFLKRPVV VTADINLSLV ALTGMGLLSR LWRLTYPRAV VFDEVYYGQY ISFYMKQIFF 
    LDDSGPPFGH MVLALGGYLG GFDGNFLWNR IGAEYSSNVP VWSLRLLPAL AGALSVPMAY 
    QIVLELHFSH CAAMGAALLM LIENALITQS RLMLLESVLI FFNLLAVLSY LKFFNCQKHS 
    PFSLSWWFWL TLTGVACSCA VGIKYMGVFT YVLVLGVAAV HAWHLLGDQT LSNVGADVQC 
    CMRPACMGQM QMSQGVCVFC HLLARAVALL VIPVVLYLLF FYVHLILVFR SGPHDQIMSS 
    AFQASLEGGL ARITQGQPLE VAFGSQVTLR NVFGKPVPCW LHSHQDTYPM IYENGRGSSH 
    QQQVTCYPFK DVNNWWIVKD PRRHQLVVSS PPRPVRHGDM VQLVHGMTTR SLNTHDVAAP 
    LSPHSQEVSC YIDYNISMPA QNLWRLEIVN RGSDTDVWKT ILSEVRFVHV NTSAVLKLSG 
    AHLPDWGYRQ LEIVGEKLSR GYHGSTVWNV EEHRYGASQE QRERERELHS PAQVDVSRNL 
    SFMARFSELQ WRMLALRSDD SEHKYSSSPL EWVTLDTNIA YWLHPRTSAQ IHLLGNIVIW 
    VSGSLALAIY ALLSLWYLLR RRRNVHDLPQ DAWLRWVLAG ALCAGGWAVN YLPFFLMEKT 
    LFLYHYLPAL TFQILLLPVV LQHISDHLCR SQLQRSIFSA LVVAWYSSAC HVSNTLRPLT 
    YGDKSLSPHE LKALRWKDSW DILIRKH

Genular Protein ID: 3279543660

Symbol: A0A140VKE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 725
  • Mass: 82567
  • Checksum: B58F992ADA9DF552
  • Sequence:
  • MWGFLKRPVV VTADINLSLV ALTGMGLLSR LWRLTYPRAV VFDEVYYGQY ISFYMKQIFF 
    LDDSGPPFGH MVLALGGYLG GFDGNFLWNR IGAEYSSNVP VWSLRLLPAL AGALSVPMAY 
    QIVLELHFSH CAAMGAALLM LIENALITQS RLMLLESVLI FFNLLAVLSY LKFFNCQKHS 
    PFSLSWWFWL TLTGVACSCA VGIKYMGVFT YVLVLGVAAV HAWHLLGDQT LSNVCVFCHL 
    LARAVALLVI PVVLYLLFFY VHLILVFRSG PHDQIMSSAF QASLEGGLAR ITQGQPLEVA 
    FGSQVTLRNV FGKPVPCWLH SHQDTYPMIY ENGRGSSHQQ QVTCYPFKDV NNWWIVKDPR 
    RHQLVVSSPP RPVRHGDMVQ LVHGMTTRSL NTHDVAAPLS PHSQEVSCYI DYNISMPAQN 
    LWRLEIVNRG SDTDVWKTIL SEVRFVHVNT SAVLKLSGAH LPDWGYRQLE IVGEKLSRGY 
    HGSTVWNVEE HRYGASQEQR ERERELHSPA QVDVSRNLSF MARFSELQWR MLALRSDDSE 
    HKYSSSPLEW VTLDTNIAYW LHPRTSAQIH LLGNIVIWVS GSLALAIYAL LSLWYLLRRR 
    RNVHDLPQDA WLRWVLAGAL CAGGWAVNYL PFFLMEKTLF LYHYLPALTF QILLLPVVLQ 
    HISDHLCRSQ LQRSIFSALV VAWYSSACHV SNTLRPLTYG DKSLSPHELK ALRWKDSWDI 
    LIRKH

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.