Details for: CENPB

Gene ID: 1059

Symbol: CENPB

Ensembl ID: ENSG00000125817

Description: centromere protein B

Associated with

Other Information

Genular Protein ID: 3451939280

Symbol: CENPB_HUMAN

Name: Major centromere autoantigen B

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 1893793

Title: CENP-B is a highly conserved mammalian centromere protein with homology to the helix-loop-helix family of proteins.

PubMed ID: 1893793

DOI: 10.1007/bf00337514

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2435739

Title: Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen.

PubMed ID: 2435739

DOI: 10.1083/jcb.104.4.817

PubMed ID: 1469042

Title: A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activity.

PubMed ID: 1469042

DOI: 10.1083/jcb.119.6.1413

PubMed ID: 18072184

Title: Assembly of the inner kinetochore proteins CENP-A and CENP-B in living human cells.

PubMed ID: 18072184

DOI: 10.1002/cbic.200700358

PubMed ID: 19412974

Title: Live-cell imaging reveals sustained centromere binding of CENP-T via CENP-A and CENP-B.

PubMed ID: 19412974

DOI: 10.1002/jbio.200810014

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23978223

Title: Identification of novel alpha-n-methylation of CENP-B that regulates its binding to the centromeric DNA.

PubMed ID: 23978223

DOI: 10.1021/pr400498y

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24522885

Title: A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.

PubMed ID: 24522885

DOI: 10.1098/rsob.130229

PubMed ID: 27499292

Title: The flexible ends of CENP-A nucleosome are required for mitotic fidelity.

PubMed ID: 27499292

DOI: 10.1016/j.molcel.2016.06.023

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 9451007

Title: A helix-turn-helix structure unit in human centromere protein B (CENP-B).

PubMed ID: 9451007

DOI: 10.1093/emboj/17.3.827

PubMed ID: 11726497

Title: Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.

PubMed ID: 11726497

DOI: 10.1093/emboj/20.23.6612

PubMed ID: 14522975

Title: Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution.

PubMed ID: 14522975

DOI: 10.1074/jbc.m310388200

Sequence Information:

  • Length: 599
  • Mass: 65171
  • Checksum: 9B4B7DB957A914AA
  • Sequence:
  • MGPKRRQLTF REKSRIIQEV EENPDLRKGE IARRFNIPPS TLSTILKNKR AILASERKYG 
    VASTCRKTNK LSPYDKLEGL LIAWFQQIRA AGLPVKGIIL KEKALRIAEE LGMDDFTASN 
    GWLDRFRRRH GVVSCSGVAR ARARNAAPRT PAAPASPAAV PSEGSGGSTT GWRAREEQPP 
    SVAEGYASQD VFSATETSLW YDFLPDQAAG LCGGDGRPRQ ATQRLSVLLC ANADGSEKLP 
    PLVAGKSAKP RAGQAGLPCD YTANSKGGVT TQALAKYLKA LDTRMAAESR RVLLLAGRLA 
    AQSLDTSGLR HVQLAFFPPG TVHPLERGVV QQVKGHYRQA MLLKAMAALE GQDPSGLQLG 
    LTEALHFVAA AWQAVEPSDI AACFREAGFG GGPNATITTS LKSEGEEEEE EEEEEEEEEG 
    EGEEEEEEGE EEEEEGGEGE ELGEEEEVEE EGDVDSDEEE EEDEESSSEG LEAEDWAQGV 
    VEAGGSFGAY GAQEEAQCPT LHFLEGGEDS DSDSEEEDDE EEDDEDEDDD DDEEDGDEVP 
    VPSFGEAMAY FAMVKRYLTS FPIDDRVQSH ILHLEHDLVH VTRKNHARQA GVRGLGHQS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.