Details for: CENPC

Gene ID: 1060

Symbol: CENPC

Ensembl ID: ENSG00000145241

Description: centromere protein C

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 314.5387
    Cell Significance Index: -48.9300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 187.0343
    Cell Significance Index: -47.4400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 112.5767
    Cell Significance Index: -53.1500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 103.9859
    Cell Significance Index: -42.2500
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 79.2373
    Cell Significance Index: -53.1700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 44.6403
    Cell Significance Index: -42.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 42.6475
    Cell Significance Index: -52.5800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.9853
    Cell Significance Index: -48.1800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.5045
    Cell Significance Index: -44.5500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.5351
    Cell Significance Index: -53.4100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 11.1990
    Cell Significance Index: -24.5100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.8143
    Cell Significance Index: 35.4100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7136
    Cell Significance Index: 23.3800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.6948
    Cell Significance Index: 339.9800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.5419
    Cell Significance Index: 19.1300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.4519
    Cell Significance Index: 64.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4398
    Cell Significance Index: 80.8000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.4118
    Cell Significance Index: 53.4600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.4117
    Cell Significance Index: 506.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.3069
    Cell Significance Index: 152.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2623
    Cell Significance Index: 137.3000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8335
    Cell Significance Index: 752.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7989
    Cell Significance Index: 158.5400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7932
    Cell Significance Index: 548.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7217
    Cell Significance Index: 130.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6921
    Cell Significance Index: 42.5400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.6899
    Cell Significance Index: 44.5100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.6462
    Cell Significance Index: 79.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6421
    Cell Significance Index: 88.1800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.6253
    Cell Significance Index: 276.4800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5992
    Cell Significance Index: 31.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.5045
    Cell Significance Index: 59.5000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4994
    Cell Significance Index: 14.3900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4765
    Cell Significance Index: 21.6000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4704
    Cell Significance Index: 36.1000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4473
    Cell Significance Index: 12.5000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4403
    Cell Significance Index: 829.0400
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.3399
    Cell Significance Index: 2.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3397
    Cell Significance Index: 22.8400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3348
    Cell Significance Index: 42.9200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3088
    Cell Significance Index: 16.2200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3081
    Cell Significance Index: 50.1200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2990
    Cell Significance Index: 29.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2882
    Cell Significance Index: 183.0600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2349
    Cell Significance Index: 5.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2197
    Cell Significance Index: 5.2700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2029
    Cell Significance Index: 110.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1857
    Cell Significance Index: 12.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1414
    Cell Significance Index: 4.9700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1173
    Cell Significance Index: 5.4700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1121
    Cell Significance Index: 50.8600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1113
    Cell Significance Index: 7.8700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0815
    Cell Significance Index: 1.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0589
    Cell Significance Index: 90.6300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0584
    Cell Significance Index: 107.6400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0302
    Cell Significance Index: 41.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0063
    Cell Significance Index: -4.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0121
    Cell Significance Index: -2.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0215
    Cell Significance Index: -3.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0530
    Cell Significance Index: -39.2600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0613
    Cell Significance Index: -46.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0630
    Cell Significance Index: -1.0800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0898
    Cell Significance Index: -17.0800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0909
    Cell Significance Index: -51.2800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0977
    Cell Significance Index: -61.0400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1336
    Cell Significance Index: -13.6500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1554
    Cell Significance Index: -4.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1580
    Cell Significance Index: -45.4700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1640
    Cell Significance Index: -7.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2112
    Cell Significance Index: -27.2900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2139
    Cell Significance Index: -10.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2194
    Cell Significance Index: -6.2900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2332
    Cell Significance Index: -14.7000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2778
    Cell Significance Index: -14.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2821
    Cell Significance Index: -59.4300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3473
    Cell Significance Index: -39.7900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3618
    Cell Significance Index: -37.6700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3729
    Cell Significance Index: -27.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5144
    Cell Significance Index: -40.7400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5209
    Cell Significance Index: -13.3900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5210
    Cell Significance Index: -14.1800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5574
    Cell Significance Index: -6.6500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.5929
    Cell Significance Index: -14.8200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.6288
    Cell Significance Index: -20.1400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6376
    Cell Significance Index: -16.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7133
    Cell Significance Index: -43.7300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7838
    Cell Significance Index: -20.9700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.8070
    Cell Significance Index: -23.0300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.8147
    Cell Significance Index: -28.3100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.8364
    Cell Significance Index: -10.4300
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.8730
    Cell Significance Index: -20.1700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.9074
    Cell Significance Index: -26.6500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.9133
    Cell Significance Index: -15.2900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.0039
    Cell Significance Index: -20.8300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.0276
    Cell Significance Index: -22.5000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.0354
    Cell Significance Index: -27.7500
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.0625
    Cell Significance Index: -13.4100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.0695
    Cell Significance Index: -15.7900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.0765
    Cell Significance Index: -27.5000
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -1.1026
    Cell Significance Index: -17.6900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CENPC is a highly conserved protein that belongs to the centromere protein family. It is characterized by its ability to bind to centromeric DNA and interact with other kinetochore proteins. CENPC is also known to regulate the activity of the spindle checkpoint, a mechanism that ensures proper chromosome segregation during mitosis. **Pathways and Functions:** CENPC is involved in several key pathways that regulate mitotic cell cycle progression. These include: 1. **Amplification of signal from the kinetochores**: CENPC helps to amplify signals from the kinetochores, ensuring that the spindle apparatus is properly attached to the chromosomes. 2. **Attachment of mitotic spindle microtubules to kinetochore**: CENPC interacts with other kinetochore proteins to facilitate the attachment of microtubules to the kinetochore. 3. **Resolution of sister chromatid cohesion**: CENPC helps to regulate the separation of sister chromatids by interacting with proteins that control the cohesion between sister chromatids. 4. **Signal transduction by Rho GTPases**: CENPC is also involved in signal transduction pathways that regulate spindle attachment and chromosome segregation in response to Rho GTPases. **Clinical Significance:** Dysregulation of CENPC has been implicated in various diseases, including cancer and neurological disorders. For example, alterations in CENPC expression have been observed in several types of cancer, including breast and ovarian cancer. Additionally, CENPC has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. In terms of its clinical significance, CENPC is a potential therapeutic target for the treatment of diseases characterized by abnormal mitotic cell cycle regulation. For example, inhibitors of CENPC have been shown to prevent the progression of cancer cells through the cell cycle, highlighting its potential as a therapeutic agent. **Significantly Expressed Cells:** CENPC is highly expressed in various cell types, including: 1. **Pigmented epithelial cells**: CENPC is highly expressed in pigmented epithelial cells, which are involved in the formation of the visual system. 2. **Non-pigmented ciliary epithelial cells**: CENPC is also expressed in non-pigmented ciliary epithelial cells, which are involved in the formation of the lens. 3. **Neuronal cells**: CENPC is highly expressed in various types of neuronal cells, including GABAergic cortical interneurons. 4. **Muscle cells**: CENPC is also expressed in muscle cells, including ciliary muscle cells. In conclusion, CENPC is a complex protein that plays a critical role in regulating mitotic cell cycle progression. Its dysregulation has been implicated in various diseases, including cancer and neurological disorders. Further research is needed to fully understand the role of CENPC in disease and to develop therapeutic strategies that target this protein.

Genular Protein ID: 2852886349

Symbol: CENPC_HUMAN

Name: Centromere protein C

UniProtKB Accession Codes:

Q03188 Q6PIR0 Q8IW27 Q9P0M5

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EMDB 12 Ensembl 2 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 14 PDBsum 14 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1339310

Title: CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate.

PubMed ID: 1339310

DOI: 10.1016/0092-8674(92)90538-n

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9645950

Title: Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.

PubMed ID: 9645950

DOI: 10.1242/jcs.111.14.2029

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16716197

Title: Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.

PubMed ID: 16716197

DOI: 10.1111/j.1365-2443.2006.00969.x

PubMed ID: 16622419

Title: The human CENP-A centromeric nucleosome-associated complex.

PubMed ID: 16622419

DOI: 10.1038/ncb1397

PubMed ID: 17651496

Title: Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres.

PubMed ID: 17651496

DOI: 10.1186/gb-2007-8-7-r148

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19503796

Title: The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.

PubMed ID: 19503796

DOI: 10.1371/journal.pone.0005832

PubMed ID: 19482874

Title: DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions.

PubMed ID: 19482874

DOI: 10.1093/hmg/ddp256

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21529714

Title: Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes.

PubMed ID: 21529714

DOI: 10.1016/j.cell.2011.03.031

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24522885

Title: A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.

PubMed ID: 24522885

DOI: 10.1098/rsob.130229

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 27499292

Title: The flexible ends of CENP-A nucleosome are required for mitotic fidelity.

PubMed ID: 27499292

DOI: 10.1016/j.molcel.2016.06.023

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 943
  • Mass: 106834
  • Checksum: 2AA5AF82BA88C809
  • Sequence:
    • MAASGLDHLK NGYRRRFCRP SRARDINTEQ GQNVLEILQD CFEEKSLAND FSTNSTKSVP 
NSTRKIKDTC IQSPSKECQK SHPKSVPVSS KKKEASLQFV VEPSEATNRS VQAHEVHQKI 
LATDVSSKNT PDSKKISSRN INDHHSEADE EFYLSVGSPS VLLDAKTSVS QNVIPSSAQK 
RETYTFENSV NMLPSSTEVS VKTKKRLNFD DKVMLKKIEI DNKVSDEEDK TSEGQERKPS 
GSSQNRIRDS EYEIQRQAKK SFSTLFLETV KRKSESSPIV RHAATAPPHS CPPDDTKLIE 
DEFIIDESDQ SFASRSWITI PRKAGSLKQR TISPAESTAL LQGRKSREKH HNILPKTLAN 
DKHSHKPHPV ETSQPSDKTV LDTSYALIGE TVNNYRSTKY EMYSKNAEKP SRSKRTIKQK 
QRRKFMAKPA EEQLDVGQSK DENIHTSHIT QDEFQRNSDR NMEEHEEMGN DCVSKKQMPP 
VGSKKSSTRK DKEESKKKRF SSESKNKLVP EEVTSTVTKS RRISRRPSDW WVVKSEESPV 
YSNSSVRNEL PMHHNSSRKS TKKTNQSSKN IRKKTIPLKR QKTATKGNQR VQKFLNAEGS 
GGIVGHDEIS RCSLSEPLES DEADLAKKKN LDCSRSTRSS KNEDNIMTAQ NVPLKPQTSG 
YTCNIPTESN LDSGEHKTSV LEESGPSRLN NNYLMSGKND VDDEEVHGSS DDSKQSKVIP 
KNRIHHKLVL PSNTPNVRRT KRTRLKPLEY WRGERIDYQG RPSGGFVISG VLSPDTISSK 
RKAKENIGKV NKKSNKKRIC LDNDERKTNL MVNLGIPLGD PLQPTRVKDP ETREIILMDL 
VRPQDTYQFF VKHGELKVYK TLDTPFFSTG KLILGPQEEK GKQHVGQDIL VFYVNFGDLL 
CTLHETPYIL STGDSFYVPS GNYYNIKNLR NEESVLLFTQ IKR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.