Details for: RBCK1
Associated with
Other Information
Genular Protein ID: 3095729290
Symbol: HOIL1_HUMAN
Name: RanBP-type and C3HC4-type zinc finger-containing protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9195957
Title: The hepatitis B virus X-associated protein, XAP3, is a protein kinase C-binding protein.
PubMed ID: 9195957
PubMed ID: 12629548
Title: Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.
PubMed ID: 12629548
DOI: 10.1038/ncb952
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14759258
PubMed ID: 15951569
Title: Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.
PubMed ID: 15951569
PubMed ID: 17006537
Title: A ubiquitin ligase complex assembles linear polyubiquitin chains.
PubMed ID: 17006537
PubMed ID: 17449468
Title: RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation.
PubMed ID: 17449468
PubMed ID: 18711448
Title: Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3.
PubMed ID: 18711448
DOI: 10.1038/cr.2008.277
PubMed ID: 20005846
Title: Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.
PubMed ID: 20005846
PubMed ID: 19136968
Title: Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation.
PubMed ID: 19136968
DOI: 10.1038/ncb1821
PubMed ID: 21455173
Title: Linear ubiquitination prevents inflammation and regulates immune signalling.
PubMed ID: 21455173
DOI: 10.1038/nature09816
PubMed ID: 21455180
Title: SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex.
PubMed ID: 21455180
DOI: 10.1038/nature09815
PubMed ID: 21455181
Title: SHARPIN forms a linear ubiquitin ligase complex regulating NF-kappaB activity and apoptosis.
PubMed ID: 21455181
DOI: 10.1038/nature09814
PubMed ID: 23104095
Title: Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
PubMed ID: 23104095
DOI: 10.1038/ni.2457
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23798481
Title: Polyglucosan body myopathy caused by defective ubiquitin ligase RBCK1.
PubMed ID: 23798481
DOI: 10.1002/ana.23963
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 23708998
Title: The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
PubMed ID: 23708998
DOI: 10.1038/nature12296
PubMed ID: 27572974
Title: Shigella flexneri suppresses NF-kappaB activation by inhibiting linear ubiquitin chain ligation.
PubMed ID: 27572974
PubMed ID: 28481331
Title: LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-kappaB.
PubMed ID: 28481331
PubMed ID: 35294289
Title: Mechanistic insights into the subversion of the linear ubiquitin chain assembly complex by the E3 ligase IpaH1.4 of Shigella flexneri.
PubMed ID: 35294289
PubMed ID: 22430200
Title: A non-canonical UBA-UBL interaction forms the linear-ubiquitin-chain assembly complex.
PubMed ID: 22430200
PubMed ID: 22517668
Title: Solution structure of the E3 ligase HOIL-1 Ubl domain.
PubMed ID: 22517668
DOI: 10.1002/pro.2080
Sequence Information:
- Length: 510
- Mass: 57572
- Checksum: C6EF957B1F152FF2
- Sequence:
MDEKTKKAEE MALSLTRAVA GGDEQVAMKC AIWLAEQRVP LSVQLKPEVS PTQDIRLWVS VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPVLQQ WVIGQRLARD QETLHSHGVR QNGDSAYLYL LSARNTSLNP QELQRERQLR MLEDLGFKDL TLQPRGPLEP GPPKPGVPQE PGRGQPDAVP EPPPVGWQCP GCTFINKPTR PGCEMCCRAR PEAYQVPASY QPDEEERARL AGEEEALRQY QQRKQQQQEG NYLQHVQLDQ RSLVLNTEPA ECPVCYSVLA PGEAVVLREC LHTFCRECLQ GTIRNSQEAE VSCPFIDNTY SCSGKLLERE IKALLTPEDY QRFLDLGISI AENRSAFSYH CKTPDCKGWC FFEDDVNEFT CPVCFHVNCL LCKAIHEQMN CKEYQEDLAL RAQNDVAARQ TTEMLKVMLQ QGEAMRCPQC QIVVQKKDGC DWIRCTVCHT EICWVTKGPR WGPGGPGDTS GGCRCRVNGI PCHPSCQNCH
Genular Protein ID: 1939394869
Symbol: A6PVJ6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
Sequence Information:
- Length: 105
- Mass: 11781
- Checksum: 763486A4E255C436
- Sequence:
MDEKTKKAEE MALSLTRAVA GGDEQVAMKC AIWLAEQRVP LSVQLKPEVS PTQDIRFLMV QNGHSSSIQP SHHRRKGRKT PLHTLLKSIA QKLYTLLPLI PVDQN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.