Details for: IGF2BP3

Gene ID: 10643

Symbol: IGF2BP3

Ensembl ID: ENSG00000136231

Description: insulin like growth factor 2 mRNA binding protein 3

Associated with

Other Information

Genular Protein ID: 3160412292

Symbol: IF2B3_HUMAN

Name: Insulin-like growth factor 2 mRNA-binding protein 3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9178771

Title: Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein.

PubMed ID: 9178771

DOI: 10.1038/sj.onc.1201110

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10525192

Title: Expression of the highly conserved RNA binding protein KOC in embryogenesis.

PubMed ID: 10525192

DOI: 10.1016/s0925-4773(99)00160-4

PubMed ID: 9891060

Title: A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

PubMed ID: 9891060

DOI: 10.1128/mcb.19.2.1262

PubMed ID: 11465943

Title: Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies.

PubMed ID: 11465943

DOI: 10.1006/clim.2001.5048

PubMed ID: 12161597

Title: Characterisation of the growth regulating gene IMP3, a candidate for Silver-Russell syndrome.

PubMed ID: 12161597

DOI: 10.1136/jmg.39.8.575

PubMed ID: 12921532

Title: Nuclear transit of human zipcode-binding protein IMP1.

PubMed ID: 12921532

DOI: 10.1042/bj20030943

PubMed ID: 15601260

Title: VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins.

PubMed ID: 15601260

DOI: 10.1042/bc20040151

PubMed ID: 15644775

Title: KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas.

PubMed ID: 15644775

DOI: 10.1097/01.pas.0000149688.98333.54

PubMed ID: 16049158

Title: Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer.

PubMed ID: 16049158

DOI: 10.1530/rep.1.00664

PubMed ID: 16541107

Title: RNA-binding IMPs promote cell adhesion and invadopodia formation.

PubMed ID: 16541107

DOI: 10.1038/sj.emboj.7601039

PubMed ID: 16814207

Title: Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study.

PubMed ID: 16814207

DOI: 10.1016/s1470-2045(06)70732-x

PubMed ID: 17192788

Title: IMP3 is a novel biomarker for adenocarcinoma in situ of the uterine cervix: an immunohistochemical study in comparison with p16(INK4a) expression.

PubMed ID: 17192788

DOI: 10.1038/modpathol.3800735

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20080952

Title: ZBP1 recognition of beta-actin zipcode induces RNA looping.

PubMed ID: 20080952

DOI: 10.1101/gad.1862910

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23640942

Title: Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains.

PubMed ID: 23640942

DOI: 10.1515/hsz-2013-0111

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 29476152

Title: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.

PubMed ID: 29476152

DOI: 10.1038/s41556-018-0045-z

Sequence Information:

  • Length: 579
  • Mass: 63705
  • Checksum: 78884F56A9D98CDE
  • Sequence:
  • MNKLYIGNLS ENAAPSDLES IFKDAKIPVS GPFLVKTGYA FVDCPDESWA LKAIEALSGK 
    IELHGKPIEV EHSVPKRQRI RKLQIRNIPP HLQWEVLDSL LVQYGVVESC EQVNTDSETA 
    VVNVTYSSKD QARQALDKLN GFQLENFTLK VAYIPDEMAA QQNPLQQPRG RRGLGQRGSS 
    RQGSPGSVSK QKPCDLPLRL LVPTQFVGAI IGKEGATIRN ITKQTQSKID VHRKENAGAA 
    EKSITILSTP EGTSAACKSI LEIMHKEAQD IKFTEEIPLK ILAHNNFVGR LIGKEGRNLK 
    KIEQDTDTKI TISPLQELTL YNPERTITVK GNVETCAKAE EEIMKKIRES YENDIASMNL 
    QAHLIPGLNL NALGLFPPTS GMPPPTSGPP SAMTPPYPQF EQSETETVHL FIPALSVGAI 
    IGKQGQHIKQ LSRFAGASIK IAPAEAPDAK VRMVIITGPP EAQFKAQGRI YGKIKEENFV 
    SPKEEVKLEA HIRVPSFAAG RVIGKGGKTV NELQNLSSAE VVVPRDQTPD ENDQVVVKIT 
    GHFYACQVAQ RKIQEILTQV KQHQQQKALQ SGPPQSRRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.