Details for: RNU7 164P

Gene ID: 106479086

Symbol: RNU7 164P

Ensembl ID: ENSG00000238730

Description: RNA, U7 small nuclear 164 pseudogene

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.0018
    Cell Significance Index: 0.0200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Pseudogene**: RNU7 164P is a pseudogene, a type of non-coding DNA sequence that lacks the ability to code for a functional protein. Despite its non-coding nature, pseudogenes can still influence gene expression and tissue development. 2. **Intestinal tissue expression**: RNU7 164P is significantly expressed in various cell types within the intestinal tissue, including enteroendocrine cells, brush cells, stromal cells, and epithelial cells. 3. **Cell type specificity**: The expression of RNU7 164P is cell type-specific, suggesting that it may play a specific role in regulating gene expression in different cell types within the intestine. 4. **Potential regulatory function**: RNU7 164P may act as a regulator of gene expression, influencing the transcriptional activity of nearby genes or participating in RNA processing pathways. **Pathways and Functions:** The exact mechanisms by which RNU7 164P regulates gene expression and maintains tissue homeostasis are unclear. However, based on its expression profile and potential regulatory function, several pathways and processes may be involved: 1. **RNA processing**: RNU7 164P may participate in RNA processing pathways, such as splicing or editing, to regulate the expression of nearby genes. 2. **Transcriptional regulation**: RNU7 164P may act as a transcriptional regulator, influencing the transcriptional activity of nearby genes or chromatin structure. 3. **Epigenetic regulation**: RNU7 164P may also participate in epigenetic regulation, influencing DNA methylation or histone modification patterns. 4. **Cell signaling**: RNU7 164P may be involved in cell signaling pathways, influencing cell growth, differentiation, or survival. **Clinical Significance:** The clinical significance of RNU7 164P is still unclear, but its expression in various cell types within the intestinal tissue suggests potential implications for human health: 1. **Intestinal disorders**: Abnormal expression of RNU7 164P may contribute to the development of intestinal disorders, such as inflammatory bowel disease (IBD) or cancer. 2. **Cancer biology**: RNU7 164P may play a role in cancer biology, influencing tumor growth, metastasis, or response to therapy. 3. **Personalized medicine**: Further research on RNU7 164P may lead to the development of personalized medicine approaches, tailored to an individual's specific genetic and environmental factors. 4. **New therapeutic targets**: The identification of RNU7 164P as a potential therapeutic target may lead to the development of new treatments for intestinal disorders or cancer. In conclusion, RNU7 164P is a fascinating pseudogene with significant implications for our understanding of intestinal tissue development and homeostasis. Further research is necessary to elucidate its mechanisms of action and clinical significance, but the potential implications for human health are substantial.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.