Details for: MTX2

Gene ID: 10651

Symbol: MTX2

Ensembl ID: ENSG00000128654

Description: metaxin 2

Associated with

Other Information

Genular Protein ID: 1256026052

Symbol: MTX2_HUMAN

Name: Metaxin-2

UniProtKB Accession Codes:

O75431 A8JZZ4 Q53S50 Q53SQ2 Q5M7Z6 Q8IZ68

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DNASU 1 DisGeNET 1 EMBL 10 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SFLD 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10381257

Title: Metaxin 1 interacts with metaxin 2, a novel related protein associated with the mammalian mitochondrial outer membrane.

PubMed ID: 10381257

DOI: 10.1002/(sici)1097-4644(19990701)74:1<11::aid-jcb2>3.3.co;2-m

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22114354

Title: MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization.

PubMed ID: 22114354

DOI: 10.1091/mbc.e11-09-0774

PubMed ID: 25997101

Title: QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.

PubMed ID: 25997101

DOI: 10.7554/elife.06265

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 32917887

Title: Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology.

PubMed ID: 32917887

DOI: 10.1038/s41467-020-18146-9

Sequence Information:

  • Length: 263
  • Mass: 29763
  • Checksum: 3A2EF476F1C78465
  • Sequence:
    • MSLVAEAFVS QIAAAEPWPE NATLYQQLKG EQILLSDNAA SLAVQAFLQM CNLPIKVVCR 
ANAEYMSPSG KVPFIHVGNQ VVSELGPIVQ FVKAKGHSLS DGLEEVQKAE MKAYMELVNN 
MLLTAELYLQ WCDEATVGEI THARYGSPYP WPLNHILAYQ KQWEVKRKMK AIGWGKKTLD 
QVLEDVDQCC QALSQRLGTQ PYFFNKQPTE LDALVFGHLY TILTTQLTND ELSEKVKNYS 
NLLAFCRRIE QHYFEDRGKG RLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.