Details for: KHDRBS1
Associated with
Other Information
Genular Protein ID: 568621641
Symbol: KHDR1_HUMAN
Name: KH domain-containing, RNA-binding, signal transduction-associated protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1374686
Title: Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62.
PubMed ID: 1374686
PubMed ID: 9013542
Title: A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain.
PubMed ID: 9013542
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9045636
Title: Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling.
PubMed ID: 9045636
PubMed ID: 10332027
Title: T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.
PubMed ID: 10332027
DOI: 10.1093/hmg/8.6.959
PubMed ID: 10913193
Title: Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability.
PubMed ID: 10913193
PubMed ID: 11585385
Title: Human leptin signaling in human peripheral blood mononuclear cells: activation of the JAK-STAT pathway.
PubMed ID: 11585385
PubMed ID: 12529443
Title: Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.
PubMed ID: 12529443
PubMed ID: 15782174
Title: Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.
PubMed ID: 15782174
DOI: 10.1038/nmeth715
PubMed ID: 15021911
Title: The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity.
PubMed ID: 15021911
PubMed ID: 16179349
Title: Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression.
PubMed ID: 16179349
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 17890166
Title: The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.
PubMed ID: 17890166
PubMed ID: 17371836
Title: The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x.
PubMed ID: 17371836
PubMed ID: 17924679
Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
PubMed ID: 17924679
DOI: 10.1021/pr070152u
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20186123
Title: The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.
PubMed ID: 20186123
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21613532
Title: The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway.
PubMed ID: 21613532
DOI: 10.1261/rna.2616111
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22253824
Title: Localization of nucleoporin Tpr to the nuclear pore complex is essential for Tpr mediated regulation of the export of unspliced RNA.
PubMed ID: 22253824
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24514149
Title: The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.
PubMed ID: 24514149
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 24129315
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
PubMed ID: 24129315
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26758068
Title: Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
PubMed ID: 26758068
DOI: 10.1038/ncomms10355
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 29496907
Title: Phosphoproteomics analysis identifies novel candidate substrates of the non-receptor tyrosine kinase, SRMS.
PubMed ID: 29496907
PubMed ID: 20610388
Title: Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
PubMed ID: 20610388
PubMed ID: 22000517
Title: Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of Sam68.
PubMed ID: 22000517
Sequence Information:
- Length: 443
- Mass: 48227
- Checksum: 59FB4DB6FB4DBE98
- Sequence:
MQRRDDPAAR MSRSSGRSGS MDPSGAHPSV RQTPSRQPPL PHRSRGGGGG SRGGARASPA TQPPPLLPPS ATGPDATVGG PAPTPLLPPS ATASVKMEPE NKYLPELMAE KDSLDPSFTH AMQLLTAEIE KIQKGDSKKD DEENYLDLFS HKNMKLKERV LIPVKQYPKF NFVGKILGPQ GNTIKRLQEE TGAKISVLGK GSMRDKAKEE ELRKGGDPKY AHLNMDLHVF IEVFGPPCEA YALMAHAMEE VKKFLVPDMM DDICQEQFLE LSYLNGVPEP SRGRGVPVRG RGAAPPPPPV PRGRGVGPPR GALVRGTPVR GAITRGATVT RGVPPPPTVR GAPAPRARTA GIQRIPLPPP PAPETYEEYG YDDTYAEQSY EGYEGYYSQS QGDSEYYDYG HGEVQDSYEA YGQDDWNGTR PSLKAPPARP VKGAYREHPY GRY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.