Details for: CELF2

Gene ID: 10659

Symbol: CELF2

Ensembl ID: ENSG00000048740

Description: CUGBP Elav-like family member 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 9.03
    Marker Score: 47,379
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 8.94
    Marker Score: 48,019
  • Cell Name: granule cell (CL0000120)
    Fold Change: 8.94
    Marker Score: 67,397
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 7.6
    Marker Score: 256,661
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 7.08
    Marker Score: 16,276
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 6.24
    Marker Score: 3,470
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 5.35
    Marker Score: 1,934
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 5.31
    Marker Score: 17,805
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 4.65
    Marker Score: 3,062
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 4.32
    Marker Score: 96,609
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 4.28
    Marker Score: 19,820
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 4.2
    Marker Score: 2,442
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 4.13
    Marker Score: 17,207
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 4.1
    Marker Score: 3,088
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 4.03
    Marker Score: 2,654
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 4.02
    Marker Score: 1,932
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 3.83
    Marker Score: 4,769
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 3.65
    Marker Score: 1,814
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 3.59
    Marker Score: 2,013
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.53
    Marker Score: 56,657
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 3.41
    Marker Score: 12,132
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.39
    Marker Score: 14,209
  • Cell Name: fat cell (CL0000136)
    Fold Change: 3.38
    Marker Score: 1,888
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.3
    Marker Score: 3,998
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.21
    Marker Score: 68,610
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.21
    Marker Score: 7,051
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 3.21
    Marker Score: 1,172
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 3.11
    Marker Score: 8,873
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 3.09
    Marker Score: 3,561
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 3.06
    Marker Score: 5,137
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.98
    Marker Score: 1,473
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.97
    Marker Score: 3,993
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.88
    Marker Score: 57,381
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 2.85
    Marker Score: 5,199
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.83
    Marker Score: 826
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.81
    Marker Score: 41,957
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.78
    Marker Score: 1,201
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.74
    Marker Score: 2,378
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.74
    Marker Score: 21,028
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.73
    Marker Score: 2,065
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.7
    Marker Score: 102,406
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.65
    Marker Score: 1,548
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.62
    Marker Score: 1,992
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.57
    Marker Score: 1,342
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 2.55
    Marker Score: 16,599
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.54
    Marker Score: 2,710
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 2.53
    Marker Score: 25,048
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.53
    Marker Score: 972
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.53
    Marker Score: 10,472
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 2.51
    Marker Score: 6,066
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.51
    Marker Score: 1,321
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.48
    Marker Score: 130,971
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.46
    Marker Score: 7,770
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.44
    Marker Score: 1,220
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.44
    Marker Score: 90,103
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 2.43
    Marker Score: 754
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.42
    Marker Score: 28,175
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2.41
    Marker Score: 6,751
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.38
    Marker Score: 2,940
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.37
    Marker Score: 2,221
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.34
    Marker Score: 23,680
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.3
    Marker Score: 1,932
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.28
    Marker Score: 1,359
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.26
    Marker Score: 6,250
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 2.24
    Marker Score: 2,704
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.24
    Marker Score: 125,444
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 2.21
    Marker Score: 9,218
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 2.2
    Marker Score: 6,423
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 2.2
    Marker Score: 1,470
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 2.18
    Marker Score: 2,718
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.18
    Marker Score: 2,146
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 2.18
    Marker Score: 4,240
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.17
    Marker Score: 20,381
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.16
    Marker Score: 8,343
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.13
    Marker Score: 892
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 2.12
    Marker Score: 2,423
  • Cell Name: activated CD8-positive, alpha-beta T cell (CL0000906)
    Fold Change: 2.11
    Marker Score: 1,532
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2.1
    Marker Score: 2,919
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 2.09
    Marker Score: 2,093
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.09
    Marker Score: 1,638
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 2.08
    Marker Score: 748
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 2.08
    Marker Score: 2,870
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.08
    Marker Score: 127,655
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 2.06
    Marker Score: 403
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 2.05
    Marker Score: 1,201
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.05
    Marker Score: 2,189
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 2.04
    Marker Score: 530
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 2.04
    Marker Score: 3,500
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.02
    Marker Score: 2,865
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.02
    Marker Score: 2,232
  • Cell Name: neuron (CL0000540)
    Fold Change: 2.02
    Marker Score: 8,221
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.99
    Marker Score: 630
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: 1.99
    Marker Score: 1,021
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.98
    Marker Score: 636
  • Cell Name: glial cell (CL0000125)
    Fold Change: 1.97
    Marker Score: 2,170
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 1.97
    Marker Score: 1,675
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.96
    Marker Score: 1,972
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.95
    Marker Score: 679
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.94
    Marker Score: 2,097
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 1.94
    Marker Score: 8,319

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CELF2 is a dual-functional RBP that exhibits both RNA-binding and RNA-processing activities. It recognizes and binds to specific RNA sequences, including 3'-UTR and splice sites, and regulates alternative splicing via the spliceosome. CELF2 has been shown to interact with various RNA molecules, including pre-mRNAs, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), and modulates their expression and function. Its ability to bind to specific RNA sequences and regulate alternative splicing makes CELF2 an important regulator of gene expression in various tissues. **Pathways and Functions:** CELF2 is involved in several key pathways, including: 1. **Regulation of Alternative mRNA Splicing:** CELF2 recognizes and binds to specific RNA sequences, including 3'-UTR and splice sites, and regulates alternative splicing via the spliceosome. This process allows CELF2 to fine-tune gene expression and confer tissue-specificity to gene expression programs. 2. **RNA Processing:** CELF2 has been shown to interact with various RNA molecules, including pre-mRNAs, miRNAs, and lncRNAs, and modulates their expression and function. This interaction allows CELF2 to regulate RNA stability, localization, and processing. 3. **Heart Contraction Regulation:** CELF2 has been shown to regulate cardiac function by modulating the expression of genes involved in heart contraction. Its ability to bind to specific RNA sequences and regulate alternative splicing makes CELF2 an important regulator of cardiac gene expression programs. **Clinical Significance:** CELF2 has been implicated in various diseases, including: 1. **Cardiac Hypertrophy:** CELF2 has been shown to regulate cardiac function and modulate the expression of genes involved in heart contraction. Dysregulation of CELF2 has been implicated in cardiac hypertrophy, a condition characterized by abnormal heart growth and function. 2. **Neurodegenerative Diseases:** CELF2 has been shown to interact with various RNA molecules, including miRNAs and lncRNAs, and modulate their expression and function. Dysregulation of CELF2 has been implicated in neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis (ALS). 3. **Cancer:** CELF2 has been shown to regulate alternative splicing and RNA processing, and its dysregulation has been implicated in cancer development and progression. In conclusion, CELF2 is a critical regulator of alternative splicing and heart contraction, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the functional roles of CELF2 and its implications in human disease.

Genular Protein ID: 871463534

Symbol: CELF2_HUMAN

Name: CUGBP Elav-like family member 2

UniProtKB Accession Codes:

O95319 B7ZAN9 Q7KYU4 Q8N499 Q92950 Q96NW9 Q96RQ5 Q96RQ6 Q9UL67

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 30 EPD 1 Ensembl 7 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 6 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 29 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 UCD-2DPAGE 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9858671

Title: Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells.

PubMed ID: 9858671

DOI: 10.1016/s0378-1119(98)00364-3

PubMed ID: 10524244

Title: Developmentally-regulated expression of mNapor encoding an apoptosis-induced ELAV-type RNA binding protein.

PubMed ID: 10524244

DOI: 10.1016/s0378-1119(99)00312-1

PubMed ID: 10893231

Title: A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator.

PubMed ID: 10893231

DOI: 10.1074/jbc.m003083200

PubMed ID: 11414768

Title: Genomic organization and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia.

PubMed ID: 11414768

DOI: 10.1006/geno.2001.6558

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8948631

Title: Identification of a (CUG)n triplet repeat RNA-binding protein and its expression in myotonic dystrophy.

PubMed ID: 8948631

DOI: 10.1093/nar/24.22.4407

PubMed ID: 11577082

Title: Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor.

PubMed ID: 11577082

DOI: 10.1074/jbc.m104911200

PubMed ID: 11158314

Title: The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing.

PubMed ID: 11158314

DOI: 10.1128/mcb.21.4.1285-1296.2001

PubMed ID: 11931771

Title: Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing.

PubMed ID: 11931771

DOI: 10.1016/s1097-2765(02)00479-3

PubMed ID: 12649496

Title: Antagonistic regulation of alpha-actinin alternative splicing by CELF proteins and polypyrimidine tract binding protein.

PubMed ID: 12649496

DOI: 10.1261/rna.2191903

PubMed ID: 14973222

Title: ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo.

PubMed ID: 14973222

DOI: 10.1093/nar/gkh275

PubMed ID: 15657417

Title: Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment.

PubMed ID: 15657417

DOI: 10.1128/mcb.25.3.879-887.2005

PubMed ID: 15894795

Title: Identification of CELF splicing activation and repression domains in vivo.

PubMed ID: 15894795

DOI: 10.1093/nar/gki561

PubMed ID: 16862542

Title: ETR-3 represses Tau exons 2/3 inclusion, a splicing event abnormally enhanced in myotonic dystrophy type I.

PubMed ID: 16862542

DOI: 10.1002/jnr.20980

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 28431233

Title: A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

PubMed ID: 28431233

DOI: 10.1016/j.molcel.2017.03.014

PubMed ID: 33131106

Title: De novo variants in CELF2 that disrupt the nuclear localization signal cause developmental and epileptic encephalopathy.

PubMed ID: 33131106

DOI: 10.1002/humu.24130

Sequence Information:

  • Length: 508
  • Mass: 54285
  • Checksum: C65F337D462717F2
  • Sequence:
    • MRCPKSAVTM RNEELLLSNG TANKMNGALD HSDQPDPDAI KMFVGQIPRS WSEKELKELF 
EPYGAVYQIN VLRDRSQNPP QSKGCCFVTF YTRKAALEAQ NALHNIKTLP GMHHPIQMKP 
ADSEKSNAVE DRKLFIGMVS KKCNENDIRV MFSPFGQIEE CRILRGPDGL SRGCAFVTFS 
TRAMAQNAIK AMHQSQTMEG CSSPIVVKFA DTQKDKEQRR LQQQLAQQMQ QLNTATWGNL 
TGLGGLTPQY LALLQQATSS SNLGAFSGIQ QMAGMNALQL QNLATLAAAA AAAQTSATST 
NANPLSTTSS ALGALTSPVA ASTPNSTAGA AMNSLTSLGT LQGLAGATVG LNNINALAGM 
AALNGGLGAT GLTNGTAGTM DALTQAYSGI QQYAAAALPT LYSQSLLQQQ SAAGSQKEGP 
EGANLFIYHL PQEFGDQDIL QMFMPFGNVI SAKVFIDKQT NLSKCFGFVS YDNPVSAQAA 
IQAMNGFQIG MKRLKVQLKR SKNDSKPY

Genular Protein ID: 3656305558

Symbol: B4DDE7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DDE7

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 DNASU 1 EMBL 2 GO 5 Gene3D 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 496
  • Mass: 52870
  • Checksum: 3B28C764BB302993
  • Sequence:
    • MVNGTANKMN GALDHSDQPD PDAIKMFVGQ IPRSWSEKEL KELFEPYGAV YQINVLRDRS 
QNPPQSKGCC FVTFYTRKAA LEAQNALHNI KTLPGMHHPI QMKPADSEKS NAVEDRKLFI 
GMVSKKCNEN DIRVMFSPFG QIEECRILRG PDGLSRGCAF VTFSTRAMAQ NAIKAMHQSQ 
TMEGCSSPIV VKFADTQKDK EQRRLQQQLA QQMQQLNTAT WGNLTGLGGL TPQYLALLQQ 
ATSSSNLGAF SGIQQMAGMN ALQLQNLATL AAAAAAAQTS ATSTNANPLS TTSSALGALT 
SPVAASTPNS TAGAAMNSLT SLGTLQGLAG ATVGLNNINA LAGTINSMAA LNGGLGATGL 
TNGTAGTMDA LTQAYSGIQQ YAAAALPTLY SQSLLQQQSA AGSQKEGPEG ANLFIYHLPQ 
EFGDQDILQM FMPFGNVISA KVFIDKQTNL SKCFGFVSYD NPVSAQAAIQ AMNGFQIGMK 
RLKVQLKRSK NDSKPY

Genular Protein ID: 101230318

Symbol: E9PC62_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PC62

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 3 GO 5 Gene3D 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 InterPro 7 MANE-Select 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 3 SMART 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 521
  • Mass: 55732
  • Checksum: 512A0B025AE6E1BA
  • Sequence:
    • MTSAFKLDFL PDMMVEGRLL VPDRINGTAN KMNGALDHSD QPDPDAIKMF VGQIPRSWSE 
KELKELFEPY GAVYQINVLR DRSQNPPQSK GCCFVTFYTR KAALEAQNAL HNIKTLPGMH 
HPIQMKPADS EKSNAVEDRK LFIGMVSKKC NENDIRVMFS PFGQIEECRI LRGPDGLSRG 
CAFVTFSTRA MAQNAIKAMH QSQTMEGCSS PIVVKFADTQ KDKEQRRLQQ QLAQQMQQLN 
TATWGNLTGL GGLTPQYLAL LQQATSSSNL GAFSGIQQMA GMNALQLQNL ATLAAAAAAA 
QTSATSTNAN PLSTTSSALG ALTSPVAAST PNSTAGAAMN SLTSLGTLQG LAGATVGLNN 
INALAVAQML SGMAALNGGL GATGLTNGTA GTMDALTQAY SGIQQYAAAA LPTLYSQSLL 
QQQSAAGSQK EGPEGANLFI YHLPQEFGDQ DILQMFMPFG NVISAKVFID KQTNLSKCFG 
FVSYDNPVSA QAAIQAMNGF QIGMKRLKVQ LKRSKNDSKP Y

Genular Protein ID: 2621878078

Symbol: A0A1B0GU44_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1B0GU44

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 520
  • Mass: 55477
  • Checksum: 971CAE54A8B39DA5
  • Sequence:
    • MVSLVSDLDP LKNWKVLRET ATELAGSLPS NGTANKMNGA LDHSDQPDPD AIKMFVGQIP 
RSWSEKELKE LFEPYGAVYQ INVLRDRSQN PPQSKGCCFV TFYTRKAALE AQNALHNIKT 
LPGMHHPIQM KPADSEKSNA VEDRKLFIGM VSKKCNENDI RVMFSPFGQI EECRILRGPD 
GLSRGCAFVT FSTRAMAQNA IKAMHQSQTM EGCSSPIVVK FADTQKDKEQ RRLQQQLAQQ 
MQQLNTATWG NLTGLGGLTP QYLALLQQAT SSSNLGAFSG IQQMAGMNAL QLQNLATLAA 
AAAAAQTSAT STNANPLSTT SSALGALTSP VAASTPNSTA GAAMNSLTSL GTLQGLAGAT 
VGLNNINALA GMAALNGGLG ATGLTNGTAG TMDALTQAYS GIQQYAAAAL PTLYSQSLLQ 
QQSAAGSQKE GPEGANLFIY HLPQEFGDQD ILQMFMPFGN VISAKVFIDK QTNLSKCFGF 
VSYDNPVSAQ AAIQAMNGFQ IGMKRLKVQL KRSKNDSKPY

Genular Protein ID: 4293946834

Symbol: B4DT00_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DT00

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 DNASU 1 EMBL 2 GO 5 Gene3D 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 6 SMART 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 484
  • Mass: 51639
  • Checksum: 59607E5C2973B3DD
  • Sequence:
    • MNGALDHSDQ PDPDAIKMFV GQIPRSWSEK ELKELFEPYG AVYQINVLRD RSQNPPQSKG 
CCFVTFYTRK AALEAQNALH NIKTLPGMHH PIQMKPADSE KSNAVEDRKL FIGMVSKKCN 
ENDIRVMFSP FGQIEECRIL RGPDGLSRGC AFVTFSTRAM AQNAIKAMHQ SQTMEGCSSP 
IVVKFADTQK DKEQRRLQQQ LAQQMQQLNT ATWGNLTGLG GLTPQYLALL QQATSSSNLG 
AFSGIQQMAG MNALQLQNLA TLAAAAAAAQ TSATSTNANP LSTTSSALGA LTSPVAASTP 
NSTAGAAMNS LTSLGTLQGL AGATVGLNNI NALAGMAALN GGLGATGLTN GTAGTMDALT 
QAYSGIQQYA AAALPTLYSQ SLLQQQSAAG SQKEGPEGAN LFIYHLPQEF GDQDILQMFM 
PFGNVISAKV FIDKQTNLSK CFGFVSYDNP VSAQAAIQAM NGFQIGMKRL KVQLKRSKND 
SKPY

Genular Protein ID: 2435395390

Symbol: B4DIB6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DIB6

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 DNASU 1 EMBL 2 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 5 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 ProteomicsDB 1 RefSeq 5 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 403
  • Mass: 42464
  • Checksum: 6B3BBE3D78FE396B
  • Sequence:
    • MHHPIQMKPA DSEKSNAVED RKLFIGMVSK KCNENDIRVM FSPFGQIEEC RILRGPDGLS 
RGCAFVTFST RAMAQNAIKA MHQSQTMEGC SSPIVVKFAD TQKDKEQRRL QQQLAQQMQQ 
LNTATWGNLT GLGGLTPQYL ALLQQATSSS NLGAFSGIQQ MAGMNALQLQ NLATLAAAAA 
AAQTSATSTN ANPLSTTSSA LGALTSPVAA STPNSTAGAA MNSLTSLGTL QGLAGATVGL 
NNINALAVAQ MLSGMAALNG GLGATGLTNG TAGTMDALTQ AYSGIQQYAA AALPTLYSQS 
LLQQQSAAGS QKEGPEGANL FIYHLPQEFG DQDILQMFMP FGNVISAKVF IDKQTNLSKC 
FGFVSYDNPV SAQAAIQAMN GFQIGMKRLK VQLKRSKNDS KPY

Genular Protein ID: 4042024563

Symbol: B4DZ01_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DZ01

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 GenomeRNAi 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 5 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 280
  • Mass: 28609
  • Checksum: 419DA8DE1C41CAA3
  • Sequence:
    • MQQLNTATWG NLTGLGGLTP QYLALLQQAT SSSNLGAFSG IQQMAGMNAL QLQNLATLAA 
AAAAAQTSAT STNANPLSTT SSALGALTSP VAASTPNSTA GAAMNSLTSL GTLQGLAGAT 
VGLNNINALA GMAALNGGLG ATGLTNGTAG TMDALTQAYS GIQQYAAAAL PTLYSQSLLQ 
QQSAAGSQKE GPEGANLFIY HLPQEFGDQD ILQMFMPFGN VISAKVFIDK QTNLSKCFGF 
VSYDNPVSAQ AAIQAMNGFQ IGMKRLKVQL KRSKNDSKPY

Genular Protein ID: 1628730835

Symbol: A0A1B0GUN8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A1B0GUN8

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 526
  • Mass: 56107
  • Checksum: 951AE8F1CD768BC1
  • Sequence:
    • MVSLVSDLDP LKNWKVLRET ATELAGSLPS NGTANKMNGA LDHSDQPDPD AIKMFVGQIP 
RSWSEKELKE LFEPYGAVYQ INVLRDRSQN PPQSKGCCFV TFYTRKAALE AQNALHNIKT 
LPGMHHPIQM KPADSEKSNA VEDRKLFIGM VSKKCNENDI RVMFSPFGQI EECRILRGPD 
GLSRGCAFVT FSTRAMAQNA IKAMHQSQTM EGCSSPIVVK FADTQKDKEQ RRLQQQLAQQ 
MQQLNTATWG NLTGLGGLTP QYLALLQQAT SSSNLGAFSG IQQMAGMNAL QLQNLATLAA 
AAAAAQTSAT STNANPLSTT SSALGALTSP VAASTPNSTA GAAMNSLTSL GTLQGLAGAT 
VGLNNINALA VAQMLSGMAA LNGGLGATGL TNGTAGTMDA LTQAYSGIQQ YAAAALPTLY 
SQSLLQQQSA AGSQKEGPEG ANLFIYHLPQ EFGDQDILQM FMPFGNVISA KVFIDKQTNL 
SKCFGFVSYD NPVSAQAAIQ AMNGFQIGMK RLKVQLKRSK NDSKPY

Genular Protein ID: 1685813731

Symbol: A0A0J9YX66_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0J9YX66

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 3 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 514
  • Mass: 54915
  • Checksum: 5CD05214DBE5CA82
  • Sequence:
    • MRCPKSAVTM RNEELLLSNG TANKMNGALD HSDQPDPDAI KMFVGQIPRS WSEKELKELF 
EPYGAVYQIN VLRDRSQNPP QSKGCCFVTF YTRKAALEAQ NALHNIKTLP GMHHPIQMKP 
ADSEKSNAVE DRKLFIGMVS KKCNENDIRV MFSPFGQIEE CRILRGPDGL SRGCAFVTFS 
TRAMAQNAIK AMHQSQTMEG CSSPIVVKFA DTQKDKEQRR LQQQLAQQMQ QLNTATWGNL 
TGLGGLTPQY LALLQQATSS SNLGAFSGIQ QMAGMNALQL QNLATLAAAA AAAQTSATST 
NANPLSTTSS ALGALTSPVA ASTPNSTAGA AMNSLTSLGT LQGLAGATVG LNNINALAVA 
QMLSGMAALN GGLGATGLTN GTAGTMDALT QAYSGIQQYA AAALPTLYSQ SLLQQQSAAG 
SQKEGPEGAN LFIYHLPQEF GDQDILQMFM PFGNVISAKV FIDKQTNLSK CFGFVSYDNP 
VSAQAAIQAM NGFQIGMKRL KVQLKRSKND SKPY

Genular Protein ID: 2976261821

Symbol: A0A0J9YXJ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0J9YXJ0

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 ChiTaRS 1 DNASU 1 EMBL 8 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 533
  • Mass: 57121
  • Checksum: AA023B0E2109ADD1
  • Sequence:
    • MTSAFKLDFL PDMMVEGRLL VPDRINGTAN KMNGALDHSD QPDPDAIKMF VGQIPRSWSE 
KELKELFEPY GAVYQINVLR DRSQNPPQSK GCCFVTFYTR KAALEAQNAL HNIKTLPGMH 
HPIQMKPADS EKSNAVEDRK LFIGMVSKKC NENDIRVMFS PFGQIEECRI LRGPDGLSRG 
CAFVTFSTRA MAQNAIKAMH QSQTMEGCSS PIVVKFADTQ KDKEQRRLQQ QLAQQMQQLN 
TATWGNLTGL GGLTPQYLAL LQQATSSSNL GAFSGIQQMA GMNALQLQNL ATLAAAAAAA 
QTSATSTNAN PLSTTSSALG ALTSPVAAST PNSTAGAAMN SLTSLGTLQG LAGATVGLNN 
INALAGTINT PRSKRLLLPK DNNGMAALNG GLGATGLTNG TAGTMDALTQ AYSGIQQYAA 
AALPTLYSQS LLQQQSAAGS QKEGPEGANL FIYHLPQEFG DQDILQMFMP FGNVISAKVF 
IDKQTNLSKC FGFVSYDNPV SAQAAIQAMN GFQIGMKRLK VQLKRSKNDS KPY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.