TNFSF13B | ENSG00000102524 | NCBI 10673

Details for: TNFSF13B

Gene ID: 10673

Symbol: TNFSF13B

Ensembl ID: ENSG00000102524

Description: TNF superfamily member 13b

Associated with

Cytokine signaling in immune system
(R-HSA-1280215)
Immune system
(R-HSA-168256)
Tnfr2 non-canonical nf-kb pathway
(R-HSA-5668541)
Tnf receptor superfamily (tnfsf) members mediating non-canonical nf-kb pathway
(R-HSA-5676594)
Tnfs bind their physiological receptors
(R-HSA-5669034)
B cell costimulation
(GO:0031296)
B cell differentiation
(GO:0030183)
B cell homeostasis
(GO:0001782)
B cell proliferation
(GO:0042100)
Cytokine activity
(GO:0005125)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Focal adhesion
(GO:0005925)
Germinal center formation
(GO:0002467)
Intracellular membrane-bounded organelle
(GO:0043231)
Membrane
(GO:0016020)
Perinuclear region of cytoplasm
(GO:0048471)
Plasma membrane
(GO:0005886)
Positive regulation of b cell proliferation
(GO:0030890)
Positive regulation of germinal center formation
(GO:0002636)
Positive regulation of t cell proliferation
(GO:0042102)
Protein binding
(GO:0005515)
Receptor ligand activity
(GO:0048018)
Signaling receptor binding
(GO:0005102)
Signal transduction
(GO:0007165)
T cell costimulation
(GO:0031295)
T cell proliferation
(GO:0042098)
Tumor necrosis factor-mediated signaling pathway
(GO:0033209)
Tumor necrosis factor receptor binding
(GO:0005164)

Other Information

Proteins

Tumor necrosis factor ligand superfamily member 13B

Genular Protein ID: 3317627347

Symbol: TN13B_HUMAN

Name: Tumor necrosis factor ligand superfamily member 13B

UniProtKB Accession Codes:

Q9Y275 E0ADT7 Q6FHD6 Q7Z5J2

Database IDs:

Citations:

PubMed ID: 10331498

Title: TALL-1 is a novel member of the TNF family that is down-regulated by mitogens.

PubMed ID: 10331498

DOI: 10.1002/jlb.65.5.680

PubMed ID: 10359578

Title: BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.

PubMed ID: 10359578

DOI: 10.1084/jem.189.11.1747

PubMed ID: 10398604

Title: BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator.

PubMed ID: 10398604

DOI: 10.1126/science.285.5425.260

PubMed ID: 12867412

Title: DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF.

PubMed ID: 12867412

DOI: 10.1074/jbc.m306852200

PubMed ID: 22749832

Title: The complexity of the BAFF TNF-family members: implications for autoimmunity.

PubMed ID: 22749832

DOI: 10.1016/j.jaut.2012.05.009

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15057823

Title: The DNA sequence and analysis of human chromosome 13.

PubMed ID: 15057823

DOI: 10.1038/nature02379

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10973284

Title: APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity.

PubMed ID: 10973284

DOI: 10.1038/79802

PubMed ID: 11853672

Title: Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.

PubMed ID: 11853672

DOI: 10.1016/s0092-8674(02)00631-1

PubMed ID: 11827482

Title: Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes.

PubMed ID: 11827482

DOI: 10.1006/jmbi.2001.5296

PubMed ID: 11862220

Title: Structural basis of BLyS receptor recognition.

PubMed ID: 11862220

DOI: 10.1038/nsb769

Sequence Information:

Length: 285
Mass: 31223
Checksum: 48ED0D7AB38C8867
Sequence:

MDDSTEREQS RLTSCLKKRE EMKLKECVSI LPRKESPSVR SSKDGKLLAA TLLLALLSCC 
LTVVSFYQVA ALQGDLASLR AELQGHHAEK LPAGAGAPKA GLEEAPAVTA GLKIFEPPAP 
GEGNSSQNSR NKRAVQGPEE TVTQDCLQLI ADSETPTIQK GSYTFVPWLL SFKRGSALEE 
KENKILVKET GYFFIYGQVL YTDKTYAMGH LIQRKKVHVF GDELSLVTLF RCIQNMPETL 
PNNSCYSAGI AKLEEGDELQ LAIPRENAQI SLDGDVTFFG ALKLL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: TNFSF13B

Associated with

Other Information

TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. PubMed ID: 10331498

BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. PubMed ID: 10359578

BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. PubMed ID: 10398604

DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF. PubMed ID: 12867412

The complexity of the BAFF TNF-family members: implications for autoimmunity. PubMed ID: 22749832

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. PubMed ID: 12975309

The DNA sequence and analysis of human chromosome 13. PubMed ID: 15057823

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. PubMed ID: 10973284

Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. PubMed ID: 11853672

Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes. PubMed ID: 11827482

Structural basis of BLyS receptor recognition. PubMed ID: 11862220