B3GNT2 | ENSG00000170340 | NCBI 10678

Details for: B3GNT2

Gene ID: 10678

Symbol: B3GNT2

Ensembl ID: ENSG00000170340

Description: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

Associated with

Glycosaminoglycan metabolism
(R-HSA-1630316)
Keratan sulfate/keratin metabolism
(R-HSA-1638074)
Keratan sulfate biosynthesis
(R-HSA-2022854)
Metabolism
(R-HSA-1430728)
Metabolism of carbohydrates
(R-HSA-71387)
Metabolism of proteins
(R-HSA-392499)
O-linked glycosylation
(R-HSA-5173105)
O-linked glycosylation of mucins
(R-HSA-913709)
Post-translational protein modification
(R-HSA-597592)
Axon guidance
(GO:0007411)
Beta-galactosyl-n-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity
(GO:0008457)
Cellular response to leukemia inhibitory factor
(GO:1990830)
Golgi membrane
(GO:0000139)
Keratan sulfate biosynthetic process
(GO:0018146)
N-acetyllactosaminide beta-1,3-n-acetylglucosaminyltransferase activity
(GO:0008532)
O-glycan processing
(GO:0016266)
Poly-n-acetyllactosamine biosynthetic process
(GO:0030311)
Protein binding
(GO:0005515)
Protein o-linked glycosylation
(GO:0006493)
Sensory perception of smell
(GO:0007608)
Udp-galactose:beta-n-acetylglucosamine beta-1,3-galactosyltransferase activity
(GO:0008499)

Other Information

Proteins

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

Genular Protein ID: 241460697

Symbol: B3GN2_HUMAN

Name: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

UniProtKB Accession Codes:

Q9NY97 Q54AC1 Q9NQQ9 Q9NQR0 Q9NUT9

Database IDs:

Citations:

PubMed ID: 9892646

Title: A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases.

PubMed ID: 9892646

DOI: 10.1073/pnas.96.2.406

PubMed ID: 11042166

Title: Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family.

PubMed ID: 11042166

DOI: 10.1074/jbc.m004800200

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10580128

Title: Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions.

PubMed ID: 10580128

DOI: 10.1016/s0304-4165(99)00168-3

PubMed ID: 14759258

Title: An unappreciated role for RNA surveillance.

PubMed ID: 14759258

DOI: 10.1186/gb-2004-5-2-r8

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 18826941

Title: Activation of beta1,3-N-acetylglucosaminyltransferase-2 (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells.

PubMed ID: 18826941

DOI: 10.1074/jbc.m806933200

PubMed ID: 25279697

Title: B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of alpha-dystroglycan.

PubMed ID: 25279697

DOI: 10.7554/elife.03943

Sequence Information:

Length: 397
Mass: 46022
Checksum: B104ECCAE26DC4AC
Sequence:

MSVGRRRIKL LGILMMANVF IYFIMEVSKS SSQEKNGKGE VIIPKEKFWK ISTPPEAYWN 
REQEKLNRQY NPILSMLTNQ TGEAGRLSNI SHLNYCEPDL RVTSVVTGFN NLPDRFKDFL 
LYLRCRNYSL LIDQPDKCAK KPFLLLAIKS LTPHFARRQA IRESWGQESN AGNQTVVRVF 
LLGQTPPEDN HPDLSDMLKF ESEKHQDILM WNYRDTFFNL SLKEVLFLRW VSTSCPDTEF 
VFKGDDDVFV NTHHILNYLN SLSKTKAKDL FIGDVIHNAG PHRDKKLKYY IPEVVYSGLY 
PPYAGGGGFL YSGHLALRLY HITDQVHLYP IDDVYTGMCL QKLGLVPEKH KGFRTFDIEE 
KNKNNICSYV DLMLVHSRKP QEMIDIWSQL QSAHLKC

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: B3GNT2

Associated with

Other Information

A beta-1,3-N-acetylglucosaminyltransferase with poly-N-acetyllactosamine synthase activity is structurally related to beta-1,3-galactosyltransferases. PubMed ID: 9892646

Identification and characterization of three novel beta 1,3-N-acetylglucosaminyltransferases structurally related to the beta 1,3-galactosyltransferase family. PubMed ID: 11042166

Generation and annotation of the DNA sequences of human chromosomes 2 and 4. PubMed ID: 15815621

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. PubMed ID: 10580128

An unappreciated role for RNA surveillance. PubMed ID: 14759258

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Activation of beta1,3-N-acetylglucosaminyltransferase-2 (beta3Gn-T2) by beta3Gn-T8. Possible involvement of beta3Gn-T8 in increasing poly-N-acetyllactosamine chains in differentiated HL-60 cells. PubMed ID: 18826941

B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of alpha-dystroglycan. PubMed ID: 25279697