Details for: FUT9

Gene ID: 10690

Symbol: FUT9

Ensembl ID: ENSG00000172461

Description: fucosyltransferase 9

Associated with

Other Information

Genular Protein ID: 2213916176

Symbol: FUT9_HUMAN

Name: Galactoside 3-L-fucosyltransferase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10386598

Title: Alpha-1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX.

PubMed ID: 10386598

DOI: 10.1016/s0014-5793(99)00640-7

PubMed ID: 10929005

Title: FUT4 and FUT9 genes are expressed early in human embryogenesis.

PubMed ID: 10929005

DOI: 10.1093/glycob/10.8.789

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10622713

Title: Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue.

PubMed ID: 10622713

DOI: 10.1016/s0014-5793(99)01549-5

PubMed ID: 11278338

Title: CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV.

PubMed ID: 11278338

DOI: 10.1074/jbc.m007272200

PubMed ID: 12107078

Title: Fuc-TIX: a versatile alpha1,3-fucosyltransferase with a distinct acceptor- and site-specificity profile.

PubMed ID: 12107078

DOI: 10.1093/glycob/12.6.361

PubMed ID: 16282604

Title: CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via Lewis x residues.

PubMed ID: 16282604

DOI: 10.1093/glycob/cwj057

PubMed ID: 17335083

Title: Increased levels of fucosyltransferase IX and carbohydrate Lewis(x) adhesion determinant in human NT2N neurons.

PubMed ID: 17335083

DOI: 10.1002/jnr.21230

PubMed ID: 18395013

Title: Human fucosyltransferase IX: specificity towards N-linked glycoproteins and relevance of the cytoplasmic domain in intra-Golgi localization.

PubMed ID: 18395013

DOI: 10.1016/j.biochi.2008.03.002

PubMed ID: 23000574

Title: Expression of glycogenes in differentiating human NT2N neurons. Downregulation of fucosyltransferase 9 leads to decreased Lewis(x) levels and impaired neurite outgrowth.

PubMed ID: 23000574

DOI: 10.1016/j.bbagen.2012.09.004

PubMed ID: 23263199

Title: N-glycosylations of human alpha1,3-fucosyltransferase IX are required for full enzyme activity.

PubMed ID: 23263199

DOI: 10.1093/glycob/cws219

PubMed ID: 23192350

Title: Silencing alpha1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion.

PubMed ID: 23192350

DOI: 10.1074/jbc.m112.400929

PubMed ID: 29593094

Title: Distinct human alpha(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.

PubMed ID: 29593094

DOI: 10.1074/jbc.ra117.000775

PubMed ID: 37202521

Title: Structural basis for Lewis antigen synthesis by the alpha1,3-fucosyltransferase FUT9.

PubMed ID: 37202521

DOI: 10.1038/s41589-023-01345-y

Sequence Information:

  • Length: 359
  • Mass: 42071
  • Checksum: D57CFCB039B644D9
  • Sequence:
  • MTSTSKGILR PFLIVCIILG CFMACLLIYI KPTNSWIFSP MESASSVLKM KNFFSTKTDY 
    FNETTILVWV WPFGQTFDLT SCQAMFNIQG CHLTTDRSLY NKSHAVLIHH RDISWDLTNL 
    PQQARPPFQK WIWMNLESPT HTPQKSGIEH LFNLTLTYRR DSDIQVPYGF LTVSTNPFVF 
    EVPSKEKLVC WVVSNWNPEH ARVKYYNELS KSIEIHTYGQ AFGEYVNDKN LIPTISTCKF 
    YLSFENSIHK DYITEKLYNA FLAGSVPVVL GPSRENYENY IPADSFIHVE DYNSPSELAK 
    YLKEVDKNNK LYLSYFNWRK DFTVNLPRFW ESHACLACDH VKRHQEYKSV GNLEKWFWN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.