Details for: CORIN

Gene ID: 10699

Symbol: CORIN

Ensembl ID: ENSG00000145244

Description: corin, serine peptidase

Associated with

Other Information

Genular Protein ID: 845413687

Symbol: CORIN_HUMAN

Name: Atrial natriuretic peptide-converting enzyme

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10329693

Title: Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart.

PubMed ID: 10329693

DOI: 10.1074/jbc.274.21.14926

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11082206

Title: Localization of the mosaic transmembrane serine protease corin to heart myocytes.

PubMed ID: 11082206

DOI: 10.1046/j.1432-1033.2000.01806.x

PubMed ID: 10880574

Title: Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme.

PubMed ID: 10880574

DOI: 10.1073/pnas.150149097

PubMed ID: 14559895

Title: Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin.

PubMed ID: 14559895

DOI: 10.1074/jbc.m309991200

PubMed ID: 17660514

Title: Role of glycosylation in corin zymogen activation.

PubMed ID: 17660514

DOI: 10.1074/jbc.m703687200

PubMed ID: 19751717

Title: Enzyme-linked immunoabsorbent assay for detection of human serine protease corin in blood.

PubMed ID: 19751717

DOI: 10.1016/j.cca.2009.09.004

PubMed ID: 20489134

Title: Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases.

PubMed ID: 20489134

DOI: 10.1373/clinchem.2010.143883

PubMed ID: 21763278

Title: Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.

PubMed ID: 21763278

DOI: 10.1016/j.bbrc.2011.06.192

PubMed ID: 21288900

Title: Ectodomain shedding and autocleavage of the cardiac membrane protease corin.

PubMed ID: 21288900

DOI: 10.1074/jbc.m110.185082

PubMed ID: 21518754

Title: Human corin isoforms with different cytoplasmic tails that alter cell surface targeting.

PubMed ID: 21518754

DOI: 10.1074/jbc.m110.217570

PubMed ID: 22437503

Title: Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy.

PubMed ID: 22437503

DOI: 10.1038/nature10897

PubMed ID: 17918732

Title: An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss.

PubMed ID: 17918732

DOI: 10.1002/humu.20617

Sequence Information:

  • Length: 1042
  • Mass: 116486
  • Checksum: A3F1CB8EBB676F78
  • Sequence:
  • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
    LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
    WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
    LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
    SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
    EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC DCNPTTEHRC GDGRCIAMEW 
    VCDGDHDCVD KSDEVNCSCH SQGLVECRNG QCIPSTFQCD GDEDCKDGSD EENCSVIQTS 
    CQEGDQRCLY NPCLDSCGGS SLCDPNNSLN NCSQCEPITL ELCMNLPYNS TSYPNYFGHR 
    TQKEASISWE SSLFPALVQT NCYKYLMFFS CTILVPKCDV NTGEHIPPCR ALCEHSKERC 
    ESVLGIVGLQ WPEDTDCSQF PEENSDNQTC LMPDEYVEEC SPSHFKCRSG QCVLASRRCD 
    GQADCDDDSD EENCGCKERD LWECPSNKQC LKHTVICDGF PDCPDYMDEK NCSFCQDDEL 
    ECANHACVSR DLWCDGEADC SDSSDEWDCV TLSINVNSSS FLMVHRAATE HHVCADGWQE 
    ILSQLACKQM GLGEPSVTKL IQEQEKEPRW LTLHSNWESL NGTTLHELLV NGQSCESRSK 
    ISLLCTKQDC GRRPAARMNK RILGGRTSRP GRWPWQCSLQ SEPSGHICGC VLIAKKWVLT 
    VAHCFEGREN AAVWKVVLGI NNLDHPSVFM QTRFVKTIIL HPRYSRAVVD YDISIVELSE 
    DISETGYVRP VCLPNPEQWL EPDTYCYITG WGHMGNKMPF KLQEGEVRII SLEHCQSYFD 
    MKTITTRMIC AGYESGTVDS CMGDSGGPLV CEKPGGRWTL FGLTSWGSVC FSKVLGPGVY 
    SNVSYFVEWI KRQIYIQTFL LN

Genular Protein ID: 2594845048

Symbol: A0A087X1D5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 938
  • Mass: 105121
  • Checksum: 943C7FC5E7D21C10
  • Sequence:
  • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
    LLVILLSYVG ACMNITHSQC QMLPYHATLT PLLSVVRNME MEKFLKFFTY LHRLSCYQHI 
    MLFGCTLAFP ECIIDGDDSH GLLPCRSFCE AAKEGCESVL GMVNYSWPDF LRCSQFRNQT 
    ESSNVSRICF SPQQENGKQL LCGRGENFLC ASGICIPGKL QCNGYNDCDD WSDEAHCNCS 
    ENLFHCHTGK CLNYSLVCDG YDDCGDLSDE QNCACHSQGL VECRNGQCIP STFQCDGDED 
    CKDGSDEENC SVIQTSCQEG DQRCLYNPCL DSCGGSSLCD PNNSLNNCSQ CEPITLELCM 
    NLPYNSTSYP NYFGHRTQKE ASISWESSLF PALVQTNCYK YLMFFSCTIL VPKCDVNTGE 
    HIPPCRALCE HSKERCESVL GIVGLQWPED TDCSQFPEEN SDNQTCLMPD EYVEECSPSH 
    FKCRSGQCVL ASRRCDGQAD CDDDSDEENC GCKERDLWEC PSNKQCLKHT VICDGFPDCP 
    DYMDEKNCSF CQDDELECAN HACVSRDLWC DGEADCSDSS DEWDCVTLSI NVNSSSFLMV 
    HRAATEHHVC ADGWQEILSQ LACKQMGLGE PSVTKLIQEQ EKEPRWLTLH SNWESLNGTT 
    LHELLVNGQS CESRSKISLL CTKQDCGRRP AARMNKRILG GRTSRPGRWP WQCSLQSEPS 
    GHICGCVLIA KKWVLTVAHC FEGRENAAVW KVVLGINNLD HPSVFMQTRF VKTIILHPRY 
    SRAVVDYDIS IVELSEDISE TGYVRPVCLP NPEQWLEPDT YCYITGWGHM GNKMPFKLQE 
    GEVRIISLEH CQSYFDMKTI TTRMICAGYE SGTVDSCMGD SGGPLVCEKP GGRWTLFGLT 
    SWGSVCFSKV LGPGVYSNVS YFVEWIKRQI YIQTFLLN

Genular Protein ID: 721894214

Symbol: B4E1Y7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 975
  • Mass: 109224
  • Checksum: D106BFF30AF933E7
  • Sequence:
  • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
    LLVILLSYVG ACMNITHSQC QMLPYHATLT PLLSVVRNME MEKFLKFFTY LHRLSCYQHI 
    MLFGCTLAFP ECIIDGDDSH GLLPCRSCCE AAKEGCESVL GMVNYSWPDF LRCSQFRNQT 
    ESSNVSRICF SPQQENGKQL LCGRGENFLC ASGICIPGKL QCNGYNDCDD WSDEAHCNCS 
    ENLFHCHTGK CLNYSLVCDG YDDCGDLSDE QNCDCNPTTE HRCGDGRCIA MEWVCDGDHD 
    CVDKSDEVNC SCHSQGLVEC RNGQCIPSTF QCDGDEDCKD GSDEENCSVI QTSCQEGDQR 
    CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP ITLELCMNLP YNSTSYPNYF GHRTQKEASI 
    SWESSLFPAL VQTNCYKYLM FFSCTILVPK CDVNTGERIP PCRALCEHSK ERCESVLGIV 
    GLQWPEDTDC SQFPEENSDN QTCLMPDEYV EECSPSHFKC RSGQCVLASR RCDGQADCDD 
    DSDEENCGCK ERDLWECPSN KQCLKHTVIC DGFPDCPDYM DEKNCSFCQD DELECANHAC 
    VSRDLWCDGE ADCSDSSDEW DCVTLSINVN SSSFLMVHRA ATEHHVCADG WQEILSQLAC 
    KQMGLGEPSV TKLIQEQEKE PRWLTLHSNW ESLNGTTLHE LLVNGQSCES RSKISLLCTK 
    QDCGRRPAAR MNKRILGGRT SRPGRWPWQC SLQSEPSGHI CGCVLIAKKW VLTVAHCFEG 
    RENAAVWKVV LGINNLDHPS VFMQTRFVKT IILHPRYSRA VVDYDISIVE LSEDISETGY 
    VRPVCLPNPE QWLEPDTYCY ITGWGHMGNK MPFKLQEGEV RIISLEHCQS YFDMKTITTR 
    MICAGYESGT VDSCMGDSGG PLVCEKPGGR WTLFGLTSWG SVCFSKVLGP GVYSNVSYFV 
    EWIKRQIYIQ TFLLN

Genular Protein ID: 2241335138

Symbol: B4E2W9_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 734
  • Mass: 81882
  • Checksum: B1A51E329D885E97
  • Sequence:
  • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
    LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
    WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
    LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
    SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
    EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC ACHSQGLVEC RNGQCIPSTF 
    QCDGDEDCKD GSDEENCSVI QTSCQEGDQR CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP 
    ITLELCMNLP YNSTSYPNYF GHRTQKEASI SWESSLFPAL VQTNCYKYLM FFSCTILVPK 
    CDVNTGEHIP PCRALCEHSK ERCESVLGIV GLQWPEDTDC SQFPEENSDN QTCLMPDEYV 
    EECSPSHFKC RSGQCVLASR RCDGQADCDD DSDEENCGCK ERDLWECPSN KQCLKHTVIC 
    DGFPDCPDYM DEKNCSFCQD DELECANHAC VSRDLWCDGE ADCSDSSDEW DCGELLVSAI 
    CCTLSCLSAT EAEWILNYFL YFTDQVHLFC FTVIKADSAD LCVLFPTHRK FPHEATSLFE 
    ISILYGKTFG FKML

Genular Protein ID: 2513692596

Symbol: J3KR83_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 734
  • Mass: 81834
  • Checksum: FCB81E329D9CD84C
  • Sequence:
  • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
    LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
    WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
    LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
    SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
    EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC ACHSQGLVEC RNGQCIPSTF 
    QCDGDEDCKD GSDEENCSVI QTSCQEGDQR CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP 
    ITLELCMNLP YNSTSYPNYF GHRTQKEASI SWESSLFPAL VQTNCYKYLM FFSCTILVPK 
    CDVNTGEHIP PCRALCEHSK ERCESVLGIV GLQWPEDTDC SQFPEENSDN QTCLMPDEYV 
    EECSPSHFKC RSGQCVLASR RCDGQADCDD DSDEENCGCK ERDLWECPSN KQCLKHTVIC 
    DGFPDCPDYM DEKNCSFCQD DELECANHAC VSRDLWCDGE ADCSDSSDEW DCGELLVSAI 
    CCTLSCLSAT EAEWILNYFL DFTDQVHLFC FTVIKADSAD LCVLFPTHRK FPHEATSLFE 
    ISILYGKTFG FKML

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.