Details for: CORIN

Gene ID: 10699

Symbol: CORIN

Ensembl ID: ENSG00000145244

Description: corin, serine peptidase

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 4.08
    Marker Score: 3,908
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.66
    Marker Score: 59,462
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 2.48
    Marker Score: 7,112
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 2.28
    Marker Score: 1,201
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.18
    Marker Score: 7,754
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.84
    Marker Score: 11,028
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1,170
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 168,043
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.43
    Marker Score: 2,714
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.41
    Marker Score: 14,610
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 872
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 1.36
    Marker Score: 1,673
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.27
    Marker Score: 857
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.26
    Marker Score: 19,766
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.18
    Marker Score: 489
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,804
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 1.11
    Marker Score: 1,606
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.1
    Marker Score: 505
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 1.08
    Marker Score: 451
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 1.07
    Marker Score: 1,383
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.04
    Marker Score: 2,117
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,808
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,033
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 0.99
    Marker Score: 363
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 511
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 464
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,407
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.97
    Marker Score: 1,664
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.96
    Marker Score: 915
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,411
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.94
    Marker Score: 376
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.93
    Marker Score: 31,569
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,312
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,739
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 328
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.88
    Marker Score: 11,681
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.87
    Marker Score: 667
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,284
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.85
    Marker Score: 2,000
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.82
    Marker Score: 295
  • Cell Name: fetal cardiomyocyte (CL0002495)
    Fold Change: 0.81
    Marker Score: 265
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,262
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 709
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.78
    Marker Score: 466
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.77
    Marker Score: 398
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.77
    Marker Score: 507
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.76
    Marker Score: 196
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.74
    Marker Score: 958
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.73
    Marker Score: 464
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.72
    Marker Score: 491
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.67
    Marker Score: 615
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: 0.66
    Marker Score: 1,722
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.65
    Marker Score: 208
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.63
    Marker Score: 973
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.6
    Marker Score: 155
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.6
    Marker Score: 475
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.59
    Marker Score: 688
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.58
    Marker Score: 2,377
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.57
    Marker Score: 1,090
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.57
    Marker Score: 150
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.56
    Marker Score: 176
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.56
    Marker Score: 673
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.55
    Marker Score: 1,570
  • Cell Name: ventricular cardiac muscle cell (CL2000046)
    Fold Change: 0.55
    Marker Score: 228
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.54
    Marker Score: 170
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.54
    Marker Score: 599
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.53
    Marker Score: 241
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.51
    Marker Score: 293
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.49
    Marker Score: 589
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.48
    Marker Score: 1,656
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.48
    Marker Score: 643
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.48
    Marker Score: 1,991
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.47
    Marker Score: 225
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.46
    Marker Score: 4,346
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.46
    Marker Score: 16,836
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.44
    Marker Score: 427
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.44
    Marker Score: 11,302
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.44
    Marker Score: 435
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.43
    Marker Score: 174
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.43
    Marker Score: 268
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.43
    Marker Score: 687
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.43
    Marker Score: 295
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.42
    Marker Score: 361
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.42
    Marker Score: 373
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.41
    Marker Score: 1,582
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.4
    Marker Score: 490
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.39
    Marker Score: 14,986
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.37
    Marker Score: 402
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.37
    Marker Score: 165
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 374
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.36
    Marker Score: 22,065
  • Cell Name: non-classical monocyte (CL0000875)
    Fold Change: 0.35
    Marker Score: 849
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.35
    Marker Score: 5,253
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.35
    Marker Score: 281
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.35
    Marker Score: 143
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.35
    Marker Score: 199
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.35
    Marker Score: 175
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.34
    Marker Score: 442
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: 0.34
    Marker Score: 188

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CORIN is a serine peptidase that exhibits endopeptidase activity, cleaving and processing peptides at the C-terminal. It is specifically involved in the conversion of pro-ANP to ANP, which is then released into the circulation to exert its physiological effects. CORIN is also implicated in the regulation of other peptides, including natriuretic peptides, vasopressin, and adrenomedullin. Its expression is widespread, with significant levels found in cardiac tissue, hematopoietic cells, and retinal cells. **Pathways and Functions:** CORIN is involved in several key pathways that regulate cardiovascular function and immune response. These include: 1. **Cardiac Conduction:** CORIN helps regulate cardiac conduction by processing ANP and other peptides that modulate the electrical activity of cardiac cells. 2. **Blood Pressure Regulation:** CORIN's conversion of pro-ANP to ANP plays a critical role in regulating blood pressure by vasodilating blood vessels and promoting sodium excretion. 3. **Electrolyte Balance:** CORIN's processing of peptides involved in electrolyte balance, such as vasopressin, helps regulate fluid balance and blood pressure. 4. **Immune Response:** CORIN's expression in hematopoietic stem cells and other immune cells suggests a role in regulating immune responses, including the processing of peptides involved in inflammation and immune cell activation. **Clinical Significance:** Dysregulation of CORIN has been implicated in various cardiovascular diseases, including: 1. **Hypertension:** Elevated levels of ANP, resulting from CORIN's dysregulation, can contribute to increased blood pressure. 2. **Heart Failure:** Impaired ANP processing and release can exacerbate cardiac dysfunction in heart failure. 3. **Cardiac Arrhythmias:** Dysregulation of CORIN can disrupt cardiac conduction, leading to arrhythmias and cardiac complications. 4. **Pregnancy Complications:** Altered ANP processing and release during pregnancy can contribute to complications such as preeclampsia and fetal growth restriction. In conclusion, CORIN plays a critical role in regulating cardiovascular function, immune response, and electrolyte balance. Its dysregulation has significant implications for the development of cardiovascular diseases, emphasizing the need for further research into the molecular mechanisms underlying CORIN's function and the potential therapeutic targeting of this gene for the treatment of related disorders.

Genular Protein ID: 845413687

Symbol: CORIN_HUMAN

Name: Atrial natriuretic peptide-converting enzyme

UniProtKB Accession Codes:

Q9Y5Q5 B0ZBE3 Q2TBD2 Q4W5E5 Q4W5G6 Q9UHY2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 Ensembl 1 ExpressionAtlas 1 GO 13 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 6 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 1 RefSeq 2 SABIO-RK 1 SAM 1 SMART 4 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 10329693

Title: Corin, a mosaic transmembrane serine protease encoded by a novel cDNA from human heart.

PubMed ID: 10329693

DOI: 10.1074/jbc.274.21.14926

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11082206

Title: Localization of the mosaic transmembrane serine protease corin to heart myocytes.

PubMed ID: 11082206

DOI: 10.1046/j.1432-1033.2000.01806.x

PubMed ID: 10880574

Title: Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme.

PubMed ID: 10880574

DOI: 10.1073/pnas.150149097

PubMed ID: 14559895

Title: Functional analysis of the transmembrane domain and activation cleavage of human corin: design and characterization of a soluble corin.

PubMed ID: 14559895

DOI: 10.1074/jbc.m309991200

PubMed ID: 17660514

Title: Role of glycosylation in corin zymogen activation.

PubMed ID: 17660514

DOI: 10.1074/jbc.m703687200

PubMed ID: 19751717

Title: Enzyme-linked immunoabsorbent assay for detection of human serine protease corin in blood.

PubMed ID: 19751717

DOI: 10.1016/j.cca.2009.09.004

PubMed ID: 20489134

Title: Processing of pro-B-type natriuretic peptide: furin and corin as candidate convertases.

PubMed ID: 20489134

DOI: 10.1373/clinchem.2010.143883

PubMed ID: 21763278

Title: Glycosylation and processing of pro-B-type natriuretic peptide in cardiomyocytes.

PubMed ID: 21763278

DOI: 10.1016/j.bbrc.2011.06.192

PubMed ID: 21288900

Title: Ectodomain shedding and autocleavage of the cardiac membrane protease corin.

PubMed ID: 21288900

DOI: 10.1074/jbc.m110.185082

PubMed ID: 21518754

Title: Human corin isoforms with different cytoplasmic tails that alter cell surface targeting.

PubMed ID: 21518754

DOI: 10.1074/jbc.m110.217570

PubMed ID: 22437503

Title: Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy.

PubMed ID: 22437503

DOI: 10.1038/nature10897

PubMed ID: 17918732

Title: An integrated genetic and functional analysis of the role of type II transmembrane serine proteases (TMPRSSs) in hearing loss.

PubMed ID: 17918732

DOI: 10.1002/humu.20617

Sequence Information:

  • Length: 1042
  • Mass: 116486
  • Checksum: A3F1CB8EBB676F78
  • Sequence:
    • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC DCNPTTEHRC GDGRCIAMEW 
VCDGDHDCVD KSDEVNCSCH SQGLVECRNG QCIPSTFQCD GDEDCKDGSD EENCSVIQTS 
CQEGDQRCLY NPCLDSCGGS SLCDPNNSLN NCSQCEPITL ELCMNLPYNS TSYPNYFGHR 
TQKEASISWE SSLFPALVQT NCYKYLMFFS CTILVPKCDV NTGEHIPPCR ALCEHSKERC 
ESVLGIVGLQ WPEDTDCSQF PEENSDNQTC LMPDEYVEEC SPSHFKCRSG QCVLASRRCD 
GQADCDDDSD EENCGCKERD LWECPSNKQC LKHTVICDGF PDCPDYMDEK NCSFCQDDEL 
ECANHACVSR DLWCDGEADC SDSSDEWDCV TLSINVNSSS FLMVHRAATE HHVCADGWQE 
ILSQLACKQM GLGEPSVTKL IQEQEKEPRW LTLHSNWESL NGTTLHELLV NGQSCESRSK 
ISLLCTKQDC GRRPAARMNK RILGGRTSRP GRWPWQCSLQ SEPSGHICGC VLIAKKWVLT 
VAHCFEGREN AAVWKVVLGI NNLDHPSVFM QTRFVKTIIL HPRYSRAVVD YDISIVELSE 
DISETGYVRP VCLPNPEQWL EPDTYCYITG WGHMGNKMPF KLQEGEVRII SLEHCQSYFD 
MKTITTRMIC AGYESGTVDS CMGDSGGPLV CEKPGGRWTL FGLTSWGSVC FSKVLGPGVY 
SNVSYFVEWI KRQIYIQTFL LN

Genular Protein ID: 2594845048

Symbol: A0A087X1D5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X1D5

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 14 MEROPS 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 7 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 4 Proteomes 2 RefSeq 1 SAM 2 SMART 4 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 938
  • Mass: 105121
  • Checksum: 943C7FC5E7D21C10
  • Sequence:
    • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
LLVILLSYVG ACMNITHSQC QMLPYHATLT PLLSVVRNME MEKFLKFFTY LHRLSCYQHI 
MLFGCTLAFP ECIIDGDDSH GLLPCRSFCE AAKEGCESVL GMVNYSWPDF LRCSQFRNQT 
ESSNVSRICF SPQQENGKQL LCGRGENFLC ASGICIPGKL QCNGYNDCDD WSDEAHCNCS 
ENLFHCHTGK CLNYSLVCDG YDDCGDLSDE QNCACHSQGL VECRNGQCIP STFQCDGDED 
CKDGSDEENC SVIQTSCQEG DQRCLYNPCL DSCGGSSLCD PNNSLNNCSQ CEPITLELCM 
NLPYNSTSYP NYFGHRTQKE ASISWESSLF PALVQTNCYK YLMFFSCTIL VPKCDVNTGE 
HIPPCRALCE HSKERCESVL GIVGLQWPED TDCSQFPEEN SDNQTCLMPD EYVEECSPSH 
FKCRSGQCVL ASRRCDGQAD CDDDSDEENC GCKERDLWEC PSNKQCLKHT VICDGFPDCP 
DYMDEKNCSF CQDDELECAN HACVSRDLWC DGEADCSDSS DEWDCVTLSI NVNSSSFLMV 
HRAATEHHVC ADGWQEILSQ LACKQMGLGE PSVTKLIQEQ EKEPRWLTLH SNWESLNGTT 
LHELLVNGQS CESRSKISLL CTKQDCGRRP AARMNKRILG GRTSRPGRWP WQCSLQSEPS 
GHICGCVLIA KKWVLTVAHC FEGRENAAVW KVVLGINNLD HPSVFMQTRF VKTIILHPRY 
SRAVVDYDIS IVELSEDISE TGYVRPVCLP NPEQWLEPDT YCYITGWGHM GNKMPFKLQE 
GEVRIISLEH CQSYFDMKTI TTRMICAGYE SGTVDSCMGD SGGPLVCEKP GGRWTLFGLT 
SWGSVCFSKV LGPGVYSNVS YFVEWIKRQI YIQTFLLN

Genular Protein ID: 721894214

Symbol: B4E1Y7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E1Y7

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 GenomeRNAi 1 InterPro 14 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 7 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 2 SMART 4 SUPFAM 4

Sequence Information:

  • Length: 975
  • Mass: 109224
  • Checksum: D106BFF30AF933E7
  • Sequence:
    • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
LLVILLSYVG ACMNITHSQC QMLPYHATLT PLLSVVRNME MEKFLKFFTY LHRLSCYQHI 
MLFGCTLAFP ECIIDGDDSH GLLPCRSCCE AAKEGCESVL GMVNYSWPDF LRCSQFRNQT 
ESSNVSRICF SPQQENGKQL LCGRGENFLC ASGICIPGKL QCNGYNDCDD WSDEAHCNCS 
ENLFHCHTGK CLNYSLVCDG YDDCGDLSDE QNCDCNPTTE HRCGDGRCIA MEWVCDGDHD 
CVDKSDEVNC SCHSQGLVEC RNGQCIPSTF QCDGDEDCKD GSDEENCSVI QTSCQEGDQR 
CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP ITLELCMNLP YNSTSYPNYF GHRTQKEASI 
SWESSLFPAL VQTNCYKYLM FFSCTILVPK CDVNTGERIP PCRALCEHSK ERCESVLGIV 
GLQWPEDTDC SQFPEENSDN QTCLMPDEYV EECSPSHFKC RSGQCVLASR RCDGQADCDD 
DSDEENCGCK ERDLWECPSN KQCLKHTVIC DGFPDCPDYM DEKNCSFCQD DELECANHAC 
VSRDLWCDGE ADCSDSSDEW DCVTLSINVN SSSFLMVHRA ATEHHVCADG WQEILSQLAC 
KQMGLGEPSV TKLIQEQEKE PRWLTLHSNW ESLNGTTLHE LLVNGQSCES RSKISLLCTK 
QDCGRRPAAR MNKRILGGRT SRPGRWPWQC SLQSEPSGHI CGCVLIAKKW VLTVAHCFEG 
RENAAVWKVV LGINNLDHPS VFMQTRFVKT IILHPRYSRA VVDYDISIVE LSEDISETGY 
VRPVCLPNPE QWLEPDTYCY ITGWGHMGNK MPFKLQEGEV RIISLEHCQS YFDMKTITTR 
MICAGYESGT VDSCMGDSGG PLVCEKPGGR WTLFGLTSWG SVCFSKVLGP GVYSNVSYFV 
EWIKRQIYIQ TFLLN

Genular Protein ID: 2241335138

Symbol: B4E2W9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E2W9

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 GenomeRNAi 1 InterPro 7 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 RefSeq 3 SAM 2 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 734
  • Mass: 81882
  • Checksum: B1A51E329D885E97
  • Sequence:
    • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC ACHSQGLVEC RNGQCIPSTF 
QCDGDEDCKD GSDEENCSVI QTSCQEGDQR CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP 
ITLELCMNLP YNSTSYPNYF GHRTQKEASI SWESSLFPAL VQTNCYKYLM FFSCTILVPK 
CDVNTGEHIP PCRALCEHSK ERCESVLGIV GLQWPEDTDC SQFPEENSDN QTCLMPDEYV 
EECSPSHFKC RSGQCVLASR RCDGQADCDD DSDEENCGCK ERDLWECPSN KQCLKHTVIC 
DGFPDCPDYM DEKNCSFCQD DELECANHAC VSRDLWCDGE ADCSDSSDEW DCGELLVSAI 
CCTLSCLSAT EAEWILNYFL YFTDQVHLFC FTVIKADSAD LCVLFPTHRK FPHEATSLFE 
ISILYGKTFG FKML

Genular Protein ID: 2513692596

Symbol: J3KR83_HUMAN

Name: N/A

UniProtKB Accession Codes:

J3KR83

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 7 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 2 SMART 2 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 734
  • Mass: 81834
  • Checksum: FCB81E329D9CD84C
  • Sequence:
    • MKQSPALAPE ERCRRAGSPK PVLRADDNNM GNGCSQKLAT ANLLRFLLLV LIPCICALVL 
LLVILLSYVG TLQKVYFKSN GSEPLVTDGE IQGSDVILTN TIYNQSTVVS TAHPDQHVPA 
WTTDASLPGD QSHRNTSACM NITHSQCQML PYHATLTPLL SVVRNMEMEK FLKFFTYLHR 
LSCYQHIMLF GCTLAFPECI IDGDDSHGLL PCRSFCEAAK EGCESVLGMV NYSWPDFLRC 
SQFRNQTESS NVSRICFSPQ QENGKQLLCG RGENFLCASG ICIPGKLQCN GYNDCDDWSD 
EAHCNCSENL FHCHTGKCLN YSLVCDGYDD CGDLSDEQNC ACHSQGLVEC RNGQCIPSTF 
QCDGDEDCKD GSDEENCSVI QTSCQEGDQR CLYNPCLDSC GGSSLCDPNN SLNNCSQCEP 
ITLELCMNLP YNSTSYPNYF GHRTQKEASI SWESSLFPAL VQTNCYKYLM FFSCTILVPK 
CDVNTGEHIP PCRALCEHSK ERCESVLGIV GLQWPEDTDC SQFPEENSDN QTCLMPDEYV 
EECSPSHFKC RSGQCVLASR RCDGQADCDD DSDEENCGCK ERDLWECPSN KQCLKHTVIC 
DGFPDCPDYM DEKNCSFCQD DELECANHAC VSRDLWCDGE ADCSDSSDEW DCGELLVSAI 
CCTLSCLSAT EAEWILNYFL DFTDQVHLFC FTVIKADSAD LCVLFPTHRK FPHEATSLFE 
ISILYGKTFG FKML

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.