Details for: ADCY1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 187.2124
Cell Significance Index: -29.1200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 114.9646
Cell Significance Index: -29.1600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 6.7885
Cell Significance Index: 148.6500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 4.8647
Cell Significance Index: 306.6100 - Cell Name: decidual cell (CL2000002)
Fold Change: 4.5813
Cell Significance Index: 73.5000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.8977
Cell Significance Index: 194.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.6236
Cell Significance Index: 526.3000 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 2.4844
Cell Significance Index: 25.8800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.8724
Cell Significance Index: 82.8200 - Cell Name: chandelier cell (CL4023083)
Fold Change: 1.7463
Cell Significance Index: 14.1000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.6935
Cell Significance Index: 64.1300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.5353
Cell Significance Index: 20.4800 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 1.4964
Cell Significance Index: 16.5100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.2808
Cell Significance Index: 36.5500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 1.2420
Cell Significance Index: 21.2900 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 1.0910
Cell Significance Index: 9.0100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.0679
Cell Significance Index: 65.6400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.0151
Cell Significance Index: 364.1100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.8591
Cell Significance Index: 594.2100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.5677
Cell Significance Index: 31.8600 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.5411
Cell Significance Index: 9.1200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.5045
Cell Significance Index: 12.1000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4532
Cell Significance Index: 44.8300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4109
Cell Significance Index: 371.0500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.3762
Cell Significance Index: 19.7500 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.3547
Cell Significance Index: 4.6000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2375
Cell Significance Index: 38.6300 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.2155
Cell Significance Index: 2.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1777
Cell Significance Index: 33.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1430
Cell Significance Index: 25.7800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1211
Cell Significance Index: 13.1800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0890
Cell Significance Index: 55.5700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.0622
Cell Significance Index: 1.3200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0563
Cell Significance Index: 1.9800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0554
Cell Significance Index: 0.6600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0553
Cell Significance Index: 10.9700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.0492
Cell Significance Index: 1.6100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0441
Cell Significance Index: 82.9600 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.0398
Cell Significance Index: 0.2700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0227
Cell Significance Index: 10.2800 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.0211
Cell Significance Index: 0.2300 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.0048
Cell Significance Index: 0.0600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0030
Cell Significance Index: 1.8900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0033
Cell Significance Index: -6.0000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0035
Cell Significance Index: -0.5900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0044
Cell Significance Index: -3.2300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0059
Cell Significance Index: -9.0200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0099
Cell Significance Index: -13.4800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0139
Cell Significance Index: -0.8500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0224
Cell Significance Index: -12.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0239
Cell Significance Index: -0.7600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0363
Cell Significance Index: -26.6500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0375
Cell Significance Index: -1.0800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0419
Cell Significance Index: -5.7600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0426
Cell Significance Index: -32.2400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0442
Cell Significance Index: -6.4200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0446
Cell Significance Index: -19.7300 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0447
Cell Significance Index: -24.4100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0666
Cell Significance Index: -14.0300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0802
Cell Significance Index: -23.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0926
Cell Significance Index: -4.2000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0929
Cell Significance Index: -5.5800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0941
Cell Significance Index: -9.8000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0962
Cell Significance Index: -1.4200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1019
Cell Significance Index: -7.0500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1055
Cell Significance Index: -2.2600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1177
Cell Significance Index: -2.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1230
Cell Significance Index: -15.1300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1334
Cell Significance Index: -1.9100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1542
Cell Significance Index: -15.7500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1586
Cell Significance Index: -8.2400 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.1759
Cell Significance Index: -2.2200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1913
Cell Significance Index: -14.6800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1955
Cell Significance Index: -25.0600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1990
Cell Significance Index: -22.8000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2101
Cell Significance Index: -6.7300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2136
Cell Significance Index: -5.9700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2146
Cell Significance Index: -24.5000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2166
Cell Significance Index: -27.9800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2179
Cell Significance Index: -25.3900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.2382
Cell Significance Index: -4.7100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2473
Cell Significance Index: -29.1600 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.2892
Cell Significance Index: -3.6500 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.2961
Cell Significance Index: -6.1800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3228
Cell Significance Index: -6.4800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.3236
Cell Significance Index: -8.0700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.3256
Cell Significance Index: -23.0300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3282
Cell Significance Index: -24.4600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3453
Cell Significance Index: -27.3500 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3468
Cell Significance Index: -8.6500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3518
Cell Significance Index: -7.6000 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3621
Cell Significance Index: -5.2000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3914
Cell Significance Index: -13.7100 - Cell Name: retinal cone cell (CL0000573)
Fold Change: -0.4109
Cell Significance Index: -5.1300 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.4148
Cell Significance Index: -4.9600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.4342
Cell Significance Index: -28.0100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.4373
Cell Significance Index: -22.7800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.4459
Cell Significance Index: -5.5300 - Cell Name: neuron (CL0000540)
Fold Change: -0.4600
Cell Significance Index: -4.3600 - Cell Name: neural cell (CL0002319)
Fold Change: -0.4607
Cell Significance Index: -5.3800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2970730296
Symbol: ADCY1_HUMAN
Name: Adenylate cyclase type 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12853948
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 8314585
Title: Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase.
PubMed ID: 8314585
PubMed ID: 11549699
Title: Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.
PubMed ID: 11549699
PubMed ID: 24482543
Title: Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish.
PubMed ID: 24482543
DOI: 10.1093/hmg/ddu042
Sequence Information:
- Length: 1119
- Mass: 123440
- Checksum: E8DDC8FCB58743D7
- Sequence:
MAGAPRGGGG GGGGAGEPGG AERAAGTSRR RGLRACDEEF ACPELEALFR GYTLRLEQAA TLKALAVLSL LAGALALAEL LGAPGPAPGL AKGSHPVHCV LFLALLVVTN VRSLQVPQLQ QVGQLALLFS LTFALLCCPF ALGGPARGSA GAAGGPATAE QGVWQLLLVT FVSYALLPVR SLLAIGFGLV VAASHLLVTA TLVPAKRPRL WRTLGANALL FVGVNMYGVF VRILTERSQR KAFLQARSCI EDRLRLEDEN EKQERLLMSL LPRNVAMEMK EDFLKPPERI FHKIYIQRHD NVSILFADIV GFTGLASQCT AQELVKLLNE LFGKFDELAT ENHCRRIKIL GDCYYCVSGL TQPKTDHAHC CVEMGLDMID TITSVAEATE VDLNMRVGLH TGRVLCGVLG LRKWQYDVWS NDVTLANVME AAGLPGKVHI TKTTLACLNG DYEVEPGYGH ERNSFLKTHN IETFFIVPSH RRKIFPGLIL SDIKPAKRMK FKTVCYLLVQ LMHCRKMFKA EIPFSNVMTC EDDDKRRALR TASEKLRNRS SFSTNVVYTT PGTRVNRYIS RLLEARQTEL EMADLNFFTL KYKHVEREQK YHQLQDEYFT SAVVLTLILA ALFGLVYLLI FPQSVVVLLL LVFCICFLVA CVLYLHITRV QCFPGCLTIQ IRTVLCIFIV VLIYSVAQGC VVGCLPWAWS SKPNSSLVVL SSGGQRTALP TLPCESTHHA LLCCLVGTLP LAIFFRVSSL PKMILLSGLT TSYILVLELS GYTRTGGGAV SGRSYEPIVA ILLFSCALAL HARQVDIRLR LDYLWAAQAE EEREDMEKVK LDNRRILFNL LPAHVAQHFL MSNPRNMDLY YQSYSQVGVM FASIPNFNDF YIELDGNNMG VECLRLLNEI IADFDELMEK DFYKDIEKIK TIGSTYMAAV GLAPTSGTKA KKSISSHLST LADFAIEMFD VLDEINYQSY NDFVLRVGIN VGPVVAGVIG ARRPQYDIWG NTVNVASRMD STGVQGRIQV TEEVHRLLRR CPYHFVCRGK VSVKGKGEML TYFLEGRTDG NGSQIRSLGL DRKMCPFGRA GLQGRRPPVC PMPGVSVRAG LPPHSPGQYL PSAAAGKEA
Genular Protein ID: 3067350381
Symbol: C9J1J0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 12853948
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 338
- Mass: 38688
- Checksum: F268F27185D9AECB
- Sequence:
MYGVFVRILT ERSQRKAFLQ ARSCIEDRLR LEDENEKQER LLMSLLPRNV AMEMKEDFLK PPERIFHKIY IQRHDNVSIL FADIVGFTGL ASQCTAQELV KLLNELFGKF DELATENHCR RIKILGDCYY CVSGLTQPKT DHAHCCVEMG LDMIDTITSV AEATEVDLNM RVGLHTGRVL CGVLGLRKWQ YDVWSNDVTL ANVMEAAGLP GKVHITKTTL ACLNGDYEVE PGYGHERNSF LKTHNIETFF IVPSHRRKIF PGLILSDIKP AKRMKFKTVC YLLVQLMHCR KMFKAEIPFS NVMTCEDDDK VQIHPSLSGL DVLLGFWSPT LQRGRLCT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.