ADCY1 | ENSG00000164742 | NCBI 107

Details for: ADCY1

Gene ID: 107

Symbol: ADCY1

Ensembl ID: ENSG00000164742

Description: adenylate cyclase 1

Associated with

Activation of gabab receptors
(R-HSA-991365)
Activation of nmda receptors and postsynaptic events
(R-HSA-442755)
Adenylate cyclase activating pathway
(R-HSA-170660)
Adenylate cyclase inhibitory pathway
(R-HSA-170670)
Adora2b mediated anti-inflammatory cytokines production
(R-HSA-9660821)
Anti-inflammatory response favouring leishmania parasite infection
(R-HSA-9662851)
Aquaporin-mediated transport
(R-HSA-445717)
Ca-dependent events
(R-HSA-111996)
Calmodulin induced events
(R-HSA-111933)
Cam pathway
(R-HSA-111997)
Creb1 phosphorylation through the activation of adenylate cyclase
(R-HSA-442720)
Dag and ip3 signaling
(R-HSA-1489509)
Disease
(R-HSA-1643685)
Fcgr3a-mediated il10 synthesis
(R-HSA-9664323)
G-protein mediated events
(R-HSA-112040)
Gaba b receptor activation
(R-HSA-977444)
Gaba receptor activation
(R-HSA-977443)
G alpha (i) signalling events
(R-HSA-418594)
G alpha (s) signalling events
(R-HSA-418555)
G alpha (z) signalling events
(R-HSA-418597)
Glucagon signaling in metabolic regulation
(R-HSA-163359)
Gpcr downstream signalling
(R-HSA-388396)
Gper1 signaling
(R-HSA-9634597)
Hedgehog 'off' state
(R-HSA-5610787)
Infectious disease
(R-HSA-5663205)
Integration of energy metabolism
(R-HSA-163685)
Intracellular signaling by second messengers
(R-HSA-9006925)
Leishmania infection
(R-HSA-9658195)
Leishmania parasite growth and survival
(R-HSA-9664433)
Metabolism
(R-HSA-1430728)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Opioid signalling
(R-HSA-111885)
Parasitic infection pathways
(R-HSA-9824443)
Pka-mediated phosphorylation of creb
(R-HSA-111931)
Pka activation
(R-HSA-163615)
Pka activation in glucagon signalling
(R-HSA-164378)
Plc beta mediated events
(R-HSA-112043)
Post nmda receptor activation events
(R-HSA-438064)
Signaling by gpcr
(R-HSA-372790)
Signaling by hedgehog
(R-HSA-5358351)
Signal transduction
(R-HSA-162582)
Transmission across chemical synapses
(R-HSA-112315)
Transport of small molecules
(R-HSA-382551)
Vasopressin regulates renal water homeostasis via aquaporins
(R-HSA-432040)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase activity
(GO:0004016)
Atp binding
(GO:0005524)
Axonogenesis
(GO:0007409)
Calcium- and calmodulin-responsive adenylate cyclase activity
(GO:0008294)
Calmodulin binding
(GO:0005516)
Camp-mediated signaling
(GO:0019933)
Camp biosynthetic process
(GO:0006171)
Cellular response to calcium ion
(GO:0071277)
Cellular response to forskolin
(GO:1904322)
Circadian rhythm
(GO:0007623)
Cytoplasm
(GO:0005737)
Extracellular exosome
(GO:0070062)
Glutamatergic synapse
(GO:0098978)
Hippocampal mossy fiber to ca3 synapse
(GO:0098686)
Long-term memory
(GO:0007616)
Membrane raft
(GO:0045121)
Metal ion binding
(GO:0046872)
Neuroinflammatory response
(GO:0150076)
Plasma membrane
(GO:0005886)
Positive regulation of creb transcription factor activity
(GO:0032793)
Positive regulation of long-term synaptic potentiation
(GO:1900273)
Postsynaptic density membrane
(GO:0098839)
Presynapse
(GO:0098793)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Regulation of circadian rhythm
(GO:0042752)
Response to xenobiotic stimulus
(GO:0009410)
Schaffer collateral - ca1 synapse
(GO:0098685)

Other Information

Proteins

Adenylate cyclase type 1
C9J1J0_HUMAN

Genular Protein ID: 2970730296

Symbol: ADCY1_HUMAN

Name: Adenylate cyclase type 1

UniProtKB Accession Codes:

Q08828 A4D2L8 Q75MI1

Database IDs:

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 8314585

Title: Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase.

PubMed ID: 8314585

DOI: 10.1006/geno.1993.1213

PubMed ID: 11549699

Title: Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.

PubMed ID: 11549699

DOI: 10.1210/jcem.86.9.7837

PubMed ID: 24482543

Title: Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish.

PubMed ID: 24482543

DOI: 10.1093/hmg/ddu042

Sequence Information:

Length: 1119
Mass: 123440
Checksum: E8DDC8FCB58743D7
Sequence:

MAGAPRGGGG GGGGAGEPGG AERAAGTSRR RGLRACDEEF ACPELEALFR GYTLRLEQAA 
TLKALAVLSL LAGALALAEL LGAPGPAPGL AKGSHPVHCV LFLALLVVTN VRSLQVPQLQ 
QVGQLALLFS LTFALLCCPF ALGGPARGSA GAAGGPATAE QGVWQLLLVT FVSYALLPVR 
SLLAIGFGLV VAASHLLVTA TLVPAKRPRL WRTLGANALL FVGVNMYGVF VRILTERSQR 
KAFLQARSCI EDRLRLEDEN EKQERLLMSL LPRNVAMEMK EDFLKPPERI FHKIYIQRHD 
NVSILFADIV GFTGLASQCT AQELVKLLNE LFGKFDELAT ENHCRRIKIL GDCYYCVSGL 
TQPKTDHAHC CVEMGLDMID TITSVAEATE VDLNMRVGLH TGRVLCGVLG LRKWQYDVWS 
NDVTLANVME AAGLPGKVHI TKTTLACLNG DYEVEPGYGH ERNSFLKTHN IETFFIVPSH 
RRKIFPGLIL SDIKPAKRMK FKTVCYLLVQ LMHCRKMFKA EIPFSNVMTC EDDDKRRALR 
TASEKLRNRS SFSTNVVYTT PGTRVNRYIS RLLEARQTEL EMADLNFFTL KYKHVEREQK 
YHQLQDEYFT SAVVLTLILA ALFGLVYLLI FPQSVVVLLL LVFCICFLVA CVLYLHITRV 
QCFPGCLTIQ IRTVLCIFIV VLIYSVAQGC VVGCLPWAWS SKPNSSLVVL SSGGQRTALP 
TLPCESTHHA LLCCLVGTLP LAIFFRVSSL PKMILLSGLT TSYILVLELS GYTRTGGGAV 
SGRSYEPIVA ILLFSCALAL HARQVDIRLR LDYLWAAQAE EEREDMEKVK LDNRRILFNL 
LPAHVAQHFL MSNPRNMDLY YQSYSQVGVM FASIPNFNDF YIELDGNNMG VECLRLLNEI 
IADFDELMEK DFYKDIEKIK TIGSTYMAAV GLAPTSGTKA KKSISSHLST LADFAIEMFD 
VLDEINYQSY NDFVLRVGIN VGPVVAGVIG ARRPQYDIWG NTVNVASRMD STGVQGRIQV 
TEEVHRLLRR CPYHFVCRGK VSVKGKGEML TYFLEGRTDG NGSQIRSLGL DRKMCPFGRA 
GLQGRRPPVC PMPGVSVRAG LPPHSPGQYL PSAAAGKEA

Genular Protein ID: 3067350381

Symbol: C9J1J0_HUMAN

Name: N/A

UniProtKB Accession Codes:

C9J1J0

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

Length: 338
Mass: 38688
Checksum: F268F27185D9AECB
Sequence:

MYGVFVRILT ERSQRKAFLQ ARSCIEDRLR LEDENEKQER LLMSLLPRNV AMEMKEDFLK 
PPERIFHKIY IQRHDNVSIL FADIVGFTGL ASQCTAQELV KLLNELFGKF DELATENHCR 
RIKILGDCYY CVSGLTQPKT DHAHCCVEMG LDMIDTITSV AEATEVDLNM RVGLHTGRVL 
CGVLGLRKWQ YDVWSNDVTL ANVMEAAGLP GKVHITKTTL ACLNGDYEVE PGYGHERNSF 
LKTHNIETFF IVPSHRRKIF PGLILSDIKP AKRMKFKTVC YLLVQLMHCR KMFKAEIPFS 
NVMTCEDDDK VQIHPSLSGL DVLLGFWSPT LQRGRLCT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ADCY1

Associated with

Other Information

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Human chromosome 7: DNA sequence and biology. PubMed ID: 12690205

Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase. PubMed ID: 8314585

Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland. PubMed ID: 11549699

Adenylate cyclase 1 (ADCY1) mutations cause recessive hearing impairment in humans and defects in hair cell function and hearing in zebrafish. PubMed ID: 24482543

The sequence of the human genome. PubMed ID: 11181995

The DNA sequence of human chromosome 7. PubMed ID: 12853948

Database document:

PubMed ID: 12853948

PubMed ID: 12690205

PubMed ID: 8314585

PubMed ID: 11549699

PubMed ID: 24482543

PubMed ID: 11181995

PubMed ID: 12853948