Details for: CETP

Gene ID: 1071

Symbol: CETP

Ensembl ID: ENSG00000087237

Description: cholesteryl ester transfer protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 8.1005
    Cell Significance Index: -1.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 4.8493
    Cell Significance Index: -1.2300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 4.6571
    Cell Significance Index: 149.1600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 4.1845
    Cell Significance Index: -1.7000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 3.6937
    Cell Significance Index: -1.9000
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 3.5525
    Cell Significance Index: 13.2400
  • Cell Name: gut endothelial cell (CL0000131)
    Fold Change: 2.0298
    Cell Significance Index: 13.9400
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 0.7676
    Cell Significance Index: 2.0300
  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 0.6262
    Cell Significance Index: 4.5900
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.5111
    Cell Significance Index: 4.0400
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.4271
    Cell Significance Index: 4.0600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4246
    Cell Significance Index: 25.4900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4047
    Cell Significance Index: 40.0400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 0.3244
    Cell Significance Index: -1.2800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.2531
    Cell Significance Index: 3.6300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2527
    Cell Significance Index: 48.0900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.1920
    Cell Significance Index: 3.2300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1845
    Cell Significance Index: 20.0700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1661
    Cell Significance Index: 1.5300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.1378
    Cell Significance Index: 8.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0896
    Cell Significance Index: 2.4000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0895
    Cell Significance Index: 6.1900
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0893
    Cell Significance Index: 1.2800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0641
    Cell Significance Index: 0.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0587
    Cell Significance Index: 10.5800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0540
    Cell Significance Index: 1.1200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0497
    Cell Significance Index: 0.3000
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.0348
    Cell Significance Index: 0.4400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0298
    Cell Significance Index: 0.8600
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.0272
    Cell Significance Index: 0.1700
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.0181
    Cell Significance Index: 0.3200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0164
    Cell Significance Index: 0.4400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0137
    Cell Significance Index: 0.4800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0131
    Cell Significance Index: 0.2800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0041
    Cell Significance Index: 0.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0029
    Cell Significance Index: 0.1500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0027
    Cell Significance Index: 0.5400
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.0007
    Cell Significance Index: 0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0002
    Cell Significance Index: 0.4600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0002
    Cell Significance Index: -0.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0004
    Cell Significance Index: -0.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0005
    Cell Significance Index: -1.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.8700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0007
    Cell Significance Index: -0.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0011
    Cell Significance Index: -1.5200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0017
    Cell Significance Index: -1.0700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0017
    Cell Significance Index: -0.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0017
    Cell Significance Index: -1.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0018
    Cell Significance Index: -0.0400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0018
    Cell Significance Index: -1.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0023
    Cell Significance Index: -1.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0024
    Cell Significance Index: -1.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0030
    Cell Significance Index: -1.3700
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0034
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0035
    Cell Significance Index: -0.5900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0039
    Cell Significance Index: -1.1300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0041
    Cell Significance Index: -0.5100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0066
    Cell Significance Index: -0.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0070
    Cell Significance Index: -1.4700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0076
    Cell Significance Index: -0.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0088
    Cell Significance Index: -1.2100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0094
    Cell Significance Index: -1.1100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0113
    Cell Significance Index: -0.5700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0115
    Cell Significance Index: -1.3200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0129
    Cell Significance Index: -1.6700
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: -0.0130
    Cell Significance Index: -0.1100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0139
    Cell Significance Index: -0.2100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0149
    Cell Significance Index: -0.6100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0160
    Cell Significance Index: -1.2300
  • Cell Name: endothelial stalk cell (CL0002671)
    Fold Change: -0.0161
    Cell Significance Index: -0.1800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0187
    Cell Significance Index: -1.2600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0189
    Cell Significance Index: -1.2200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0212
    Cell Significance Index: -1.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0212
    Cell Significance Index: -0.9900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0213
    Cell Significance Index: -1.3100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0225
    Cell Significance Index: -1.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0226
    Cell Significance Index: -1.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0228
    Cell Significance Index: -1.7000
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0237
    Cell Significance Index: -0.3000
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0248
    Cell Significance Index: -0.3400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0253
    Cell Significance Index: -1.4200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0268
    Cell Significance Index: -1.1700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0297
    Cell Significance Index: -0.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0301
    Cell Significance Index: -0.8400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0305
    Cell Significance Index: -1.0700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0314
    Cell Significance Index: -1.3900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0330
    Cell Significance Index: -1.0800
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0333
    Cell Significance Index: -0.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0336
    Cell Significance Index: -1.0700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0338
    Cell Significance Index: -1.2400
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.0358
    Cell Significance Index: -0.4400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0358
    Cell Significance Index: -1.3600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0368
    Cell Significance Index: -0.6800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0396
    Cell Significance Index: -0.4500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0404
    Cell Significance Index: -1.0800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0420
    Cell Significance Index: -1.0800
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: -0.0429
    Cell Significance Index: -0.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0432
    Cell Significance Index: -0.7400
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: -0.0437
    Cell Significance Index: -0.4000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CETP is a transmembrane protein that is expressed in various cells, including gut endothelial cells, Kupffer cells, colon goblet cells, and enterocytes. It has a unique structure, consisting of two transmembrane domains and a cytoplasmic domain. CETP is able to bind to both cholesteryl esters and phospholipids, and it has a high affinity for phospholipids. The protein is also able to undergo dimerization, which allows it to transfer cholesteryl esters and phospholipids between HDL and LDL particles. **Pathways and Functions** CETP is involved in several key pathways, including: 1. **Cholesterol Homeostasis**: CETP plays a crucial role in maintaining cholesterol homeostasis by regulating the transfer of cholesteryl esters between HDL and LDL particles. 2. **Cholesterol Transport**: CETP is involved in the regulation of reverse cholesterol transport, a process by which excess cholesterol is transported from peripheral tissues to the liver for excretion. 3. **Phospholipid Homeostasis**: CETP plays a role in maintaining phospholipid homeostasis by regulating the transfer of phospholipids between HDL and LDL particles. 4. **Lipid Transport**: CETP is involved in the regulation of lipid transport by facilitating the transfer of cholesteryl esters and phospholipids between HDL and LDL particles. **Clinical Significance** Dysregulation of CETP has been implicated in various diseases, including: 1. **Atherosclerosis**: CETP has been shown to play a role in the development of atherosclerosis by facilitating the transfer of cholesteryl esters from HDL to LDL particles, which can lead to the accumulation of excess cholesterol in the arterial wall. 2. **Hyperlipidemia**: CETP has been shown to play a role in the development of hyperlipidemia by facilitating the transfer of cholesteryl esters from HDL to LDL particles, which can lead to the accumulation of excess cholesterol in the bloodstream. 3. **Cardiovascular Disease**: CETP has been shown to play a role in the development of cardiovascular disease by facilitating the transfer of cholesteryl esters from HDL to LDL particles, which can lead to the accumulation of excess cholesterol in the arterial wall. 4. **Cognitive Decline**: CETP has been shown to play a role in the development of cognitive decline by facilitating the transfer of cholesteryl esters from HDL to LDL particles, which can lead to the accumulation of excess cholesterol in the brain. In conclusion, CETP is a multifunctional protein that plays a crucial role in the regulation of cholesterol and phospholipid homeostasis in the body. Dysregulation of CETP has been implicated in various diseases, including atherosclerosis, hyperlipidemia, cardiovascular disease, and cognitive decline. Further research is needed to fully understand the role of CETP in these diseases and to develop effective therapeutic strategies to modulate CETP activity.

Genular Protein ID: 2056490035

Symbol: CETP_HUMAN

Name: N/A

UniProtKB Accession Codes:

P11597 Q13987 Q13988 Q53YZ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 3 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 13 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 1 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 3 RefSeq 1 Rhea 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3600759

Title: Cloning and sequencing of human cholesteryl ester transfer protein cDNA.

PubMed ID: 3600759

DOI: 10.1038/327632a0

PubMed ID: 2334701

Title: Organization of the human cholesteryl ester transfer protein gene.

PubMed ID: 2334701

DOI: 10.1021/bi00458a004

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8943225

Title: Human cholesteryl ester transfer protein gene proximal promoter contains dietary cholesterol positive responsive elements and mediates expression in small intestine and periphery while predominant liver and spleen expression is controlled by 5'-distal sequences. Cis-acting sequences mapped in transgenic mice.

PubMed ID: 8943225

DOI: 10.1074/jbc.271.50.31831

PubMed ID: 9332354

Title: Sequencing of the cholesteryl ester transfer protein 5' regulatory region using artificial transposons.

PubMed ID: 9332354

DOI: 10.1016/s0378-1119(97)00247-3

PubMed ID: 3281933

Title: Monoclonal antibodies to the Mr 74,000 cholesteryl ester transfer protein neutralize all of the cholesteryl ester and triglyceride transfer activities in human plasma.

PubMed ID: 3281933

DOI: 10.1016/s0021-9258(18)60670-2

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17952847

Title: Common single-nucleotide polymorphisms act in concert to affect plasma levels of high-density lipoprotein cholesterol.

PubMed ID: 17952847

DOI: 10.1086/522497

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 24293641

Title: Cholesteryl ester transfer proteins from different species do not have equivalent activities.

PubMed ID: 24293641

DOI: 10.1194/jlr.m043646

PubMed ID: 17237796

Title: Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.

PubMed ID: 17237796

DOI: 10.1038/nsmb1197

PubMed ID: 2215607

Title: Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation.

PubMed ID: 2215607

DOI: 10.1056/nejm199011013231803

PubMed ID: 8408659

Title: A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins.

PubMed ID: 8408659

DOI: 10.1172/jci116802

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 12091484

Title: Two novel missense mutations in the CETP gene in Japanese hyperalphalipoproteinemic subjects: high-throughput assay by Invader assay.

PubMed ID: 12091484

DOI: 10.1194/jlr.m200024-jlr200

PubMed ID: 12966036

Title: Association of extreme blood lipid profile phenotypic variation with 11 reverse cholesterol transport genes and 10 non-genetic cardiovascular disease risk factors.

PubMed ID: 12966036

DOI: 10.1093/hmg/ddg314

Sequence Information:

  • Length: 493
  • Mass: 54756
  • Checksum: CD7762766A9B062E
  • Sequence:
    • MLAATVLTLA LLGNAHACSK GTSHEAGIVC RITKPALLVL NHETAKVIQT AFQRASYPDI 
TGEKAMMLLG QVKYGLHNIQ ISHLSIASSQ VELVEAKSID VSIQNVSVVF KGTLKYGYTT 
AWWLGIDQSI DFEIDSAIDL QINTQLTCDS GRVRTDAPDC YLSFHKLLLH LQGEREPGWI 
KQLFTNFISF TLKLVLKGQI CKEINVISNI MADFVQTRAA SILSDGDIGV DISLTGDPVI 
TASYLESHHK GHFIYKNVSE DLPLPTFSPT LLGDSRMLYF WFSERVFHSL AKVAFQDGRL 
MLSLMGDEFK AVLETWGFNT NQEIFQEVVG GFPSQAQVTV HCLKMPKISC QNKGVVVNSS 
VMVKFLFPRP DQQHSVAYTF EEDIVTTVQA SYSKKKLFLS LLDFQITPKT VSNLTESSSE 
SVQSFLQSMI TAVGIPEVMS RLEVVFTALM NSKGVSLFDI INPEIITRDG FLLLQMDFGF 
PEHLLVDFLQ SLS

Genular Protein ID: 1429060837

Symbol: B4DMZ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DMZ5

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 2 GO 17 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 3 SMART 4 SUPFAM 1

Sequence Information:

  • Length: 433
  • Mass: 47801
  • Checksum: 36C4476AE66F78E5
  • Sequence:
    • MLAATVLTLA LLGNAHACSK GTSHEAGIVC RITKPALLVL NHETAKVIQT AFQRASYPDI 
TGEKAMMLLG QVKYGLHNIQ ISHLSIASSQ VELVEAKSID VSIQNVSVVF KGTLKYGYTT 
AWWLGIDQSI DFEIDSAIDL QINTQLTCDS GRVRTDAPDC YLSFHKLLLH LQGEREPGWI 
KQLFTNFISF TLKLVLKGQI CKEINVISNI MADFVQTRAA SILSDGDIGV DISLTGDPVI 
TASYLESHHK AVLETWGFNT NQEIFQEVVG GFPSQAQVTV HCLKMPKISC QNKGVVVNSS 
VMVKFLFPRP DQQHSVAYTF EEDIVTTVQA SYSKKKLFLS LLDFQITPKT VSNLTESSSE 
SIQSFLQSMI TAVGIPEVMS RLEVVFTALM NSKGVSLFDI INPEIITRDG FLLLQMDFGF 
PEHLLVDFLQ SLS

Genular Protein ID: 971611158

Symbol: A0A0S2Z3I8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z3I8

Database IDs:

ARBA 15 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 3 DNASU 1 DisGeNET 1 EMBL 4 ExpressionAtlas 1 GO 17 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PROSITE 1 Pfam 1 RefSeq 1 Rhea 3 SAM 1 SMART 4 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 433
  • Mass: 47787
  • Checksum: ED675FD1456F78F7
  • Sequence:
    • MLAATVLTLA LLGNAHACSK GTSHEAGIVC RITKPALLVL NHETAKVIQT AFQRASYPDI 
TGEKAMMLLG QVKYGLHNIQ ISHLSIASSQ VELVEAKSID VSIQNVSVVF KGTLKYGYTT 
AWWLGIDQSI DFEIDSAIDL QINTQLTCDS GRVRTDAPDC YLSFHKLLLH LQGEREPGWI 
KQLFTNFISF TLKLVLKGQI CKEINVISNI MADFVQTRAA SILSDGDIGV DISLTGDPVI 
TASYLESHHK AVLETWGFNT NQEIFQEVVG GFPSQAQVTV HCLKMPKISC QNKGVVVNSS 
VMVKFLFPRP DQQHSVAYTF EEDIVTTVQA SYSKKKLFLS LLDFQITPKT VSNLTESSSE 
SVQSFLQSMI TAVGIPEVMS RLEVVFTALM NSKGVSLFDI INPEIITRDG FLLLQMDFGF 
PEHLLVDFLQ SLS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.