Details for: USP39

Gene ID: 10713

Symbol: USP39

Ensembl ID: ENSG00000168883

Description: ubiquitin specific peptidase 39

Associated with

Other Information

Genular Protein ID: 259176324

Symbol: UBP39_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53GS9 A8K086 B3KM40 B4DHT4 D6W5L4 G5E9H0 Q6NX47 Q96RK9 Q9BV89 Q9H381 Q9P050 Q9Y310

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChEBI 4 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 16 EMDB 3 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 2 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 4 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 10 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11350945

Title: The 65 and 110 kDa SR-related proteins of the U4/U6*U5 tri-snRNP are essential for the assembly of mature spliceosomes.

PubMed ID: 11350945

DOI: 10.1093/emboj/20.10.2553

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16723661

Title: The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.

PubMed ID: 16723661

DOI: 10.1261/rna.55406

PubMed ID: 18728397

Title: Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B.

PubMed ID: 18728397

DOI: 10.4161/cc.7.17.6553

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30771428

Title: USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.

PubMed ID: 30771428

DOI: 10.1016/j.canlet.2019.02.015

PubMed ID: 33127822

Title: USP39 Serves as a Deubiquitinase to Stabilize STAT1 and Sustains Type I IFN-Induced Antiviral Immunity.

PubMed ID: 33127822

DOI: 10.4049/jimmunol.1901384

PubMed ID: 34614178

Title: USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing.

PubMed ID: 34614178

DOI: 10.1093/nar/gkab892

PubMed ID: 36651806

Title: USP39 Regulates NF-kappaB-Mediated Inflammatory Responses through Deubiquitinating K48-Linked IkappaBalpha.

PubMed ID: 36651806

DOI: 10.4049/jimmunol.2200603

PubMed ID: 26912367

Title: Molecular architecture of the human U4/U6.U5 tri-snRNP.

PubMed ID: 26912367

DOI: 10.1126/science.aad2085

Sequence Information:

  • Length: 565
  • Mass: 65381
  • Checksum: 8946FD5DCDEFD0B0
  • Sequence:
    • MSGRSKRESR GSTRGKRESE SRGSSGRVKR ERDREREPEA ASSRGSPVRV KREFEPASAR 
EAPASVVPFV RVKREREVDE DSEPEREVRA KNGRVDSEDR RSRHCPYLDT INRSVLDFDF 
EKLCSISLSH INAYACLVCG KYFQGRGLKS HAYIHSVQFS HHVFLNLHTL KFYCLPDNYE 
IIDSSLEDIT YVLKPTFTKQ QIANLDKQAK LSRAYDGTTY LPGIVGLNNI KANDYANAVL 
QALSNVPPLR NYFLEEDNYK NIKRPPGDIM FLLVQRFGEL MRKLWNPRNF KAHVSPHEML 
QAVVLCSKKT FQITKQGDGV DFLSWFLNAL HSALGGTKKK KKTIVTDVFQ GSMRIFTKKL 
PHPDLPAEEK EQLLHNDEYQ ETMVESTFMY LTLDLPTAPL YKDEKEQLII PQVPLFNILA 
KFNGITEKEY KTYKENFLKR FQLTKLPPYL IFCIKRFTKN NFFVEKNPTI VNFPITNVDL 
REYLSEEVQA VHKNTTYDLI ANIVHDGKPS EGSYRIHVLH HGTGKWYELQ DLQVTDILPQ 
MITLSEAYIQ IWKRRDNDET NQQGA

Genular Protein ID: 3708301868

Symbol: B7Z7L9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7L9

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EC 1 EMBL 2 GO 4 Gene3D 2 GenomeRNAi 1 InterPro 6 MEROPS 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 487
  • Mass: 56384
  • Checksum: 68DCBAB6923C9DF7
  • Sequence:
    • MLTAVPSHLF SAKNGRVDSE DRRSRHCPYL DTINRSVLDF DFEKLCSISL SHINAYACLV 
CGKYFQGRGL KSHAYIHSVQ FSHHVFLNLH TLKFYCLPDN YEIIDSSLED ITYVLKPTFT 
KQQIANLDKQ AKLSRAYDGT TYLPGIVGLN NIKANDYANA VLQALSNVPP LRNYFLEEDN 
YKNIKRPPGD IMFLLVQRFG ELMRKLWNPR NFKAHVSPHE MLQAVVLCSK KTFQITKQGD 
GVDFLSWFLN APHSALGGTK KKKKTIVTDV FQGSMRIFTK KLPHPDLPAE EKEQLLHNDE 
YQETMVESTF MYLTLDLPTA PLYKDEKEQL IIPQVPLFNI LAKFNGITEK EYKTYKENFL 
KRFQLTKLPP YLIFCIKRFT KNNFFVEKNP TIVNFPITNV DLREYLSEEV QAVHKNTTYD 
LIANIVHDGK PSEGSYRIHV LHHGTGKWYE LQDLQVTDIL PQMITLSEAY IQIWKRRDND 
ETNQQGA

Genular Protein ID: 334846892

Symbol: A0A087X1B2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X1B2

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EC 1 EMBL 2 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 6 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 487
  • Mass: 56400
  • Checksum: 48DCBAB053908739
  • Sequence:
    • MLTAVPSHLF SAKNGRVDSE DRRSRHCPYL DTINRSVLDF DFEKLCSISL SHINAYACLV 
CGKYFQGRGL KSHAYIHSVQ FSHHVFLNLH TLKFYCLPDN YEIIDSSLED ITYVLKPTFT 
KQQIANLDKQ AKLSRAYDGT TYLPGIVGLN NIKANDYANA VLQALSNVPP LRNYFLEEDN 
YKNIKRPPGD IMFLLVQRFG ELMRKLWNPR NFKAHVSPHE MLQAVVLCSK KTFQITKQGD 
GVDFLSWFLN ALHSALGGTK KKKKTIVTDV FQGSMRIFTK KLPHPDLPAE EKEQLLHNDE 
YQETMVESTF MYLTLDLPTA PLYKDEKEQL IIPQVPLFNI LAKFNGITEK EYKTYKENFL 
KRFQLTKLPP YLIFCIKRFT KNNFFVEKNP TIVNFPITNV DLREYLSEEV QAVHKNTTYD 
LIANIVHDGK PSEGSYRIHV LHHGTGKWYE LQDLQVTDIL PQMITLSEAY IQIWKRRDND 
ETNQQGA

Genular Protein ID: 224103630

Symbol: B3KPG7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KPG7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 1 Gene3D 1 GenomeRNAi 1 InterPro 3 MEROPS 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 5 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 296
  • Mass: 34655
  • Checksum: A68A94015567C26E
  • Sequence:
    • MFLLVQRFGE LMRKLWNPRN FKAHVSPHEM LQAVVLCSKK TFQITKQGDG VDFLSWFLNA 
LHSALGGTKK KKKTIVTDVF QGSMRIFTKK LPHPDLPAEE KEQLLHNDEY QETMVESTFM 
YLTLDLPTAP LYKDEKEQLI IPQVPLFNIL AKFNGITEKE YKTYKENFLK RFQLTKLPPY 
LIFCIKRFTK NNFFVEKNPT IVNFPITNVD LREYLSEEVQ AVHKNTTYDL IANIVHDGKP 
SEGSYRIHVL HHGTGKWYEL QDLQVTDILP QMITLSEAYI QIWKRRDNDE TNQQGA

Genular Protein ID: 1216778518

Symbol: B3KMG1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMG1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 GenomeRNAi 1 InterPro 3 MEROPS 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 296
  • Mass: 34683
  • Checksum: EBBA90F4C157C848
  • Sequence:
    • MFLLVQRFGE LMRKLWNPRN FRAHVSPHEM LQAVVLCSKK TFQITKQGDG VDFLSWFLNA 
LHSALGGTKK KKKTIVTDVF QGSMRIFTKK LPHPDLPAEE KEQLLHNDEY QETMVESTFM 
YLTLDLPTAP LYKDEKEQLI IPQVPLFNIL AKFNGITEKE YKTYKENFLK RFQLTKLPPY 
LIFCIKRFTK NNFFVEKNPT IVNFPITNVD LREYLSEEVQ AVHKNTTYDL IANIVHDGKP 
SEGSYRIHVL HHGTGKWYEL QDLQVTDILP QMITLSEAYI QIWKRRDNDE TNQQGA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.