SLC12A7 | ENSG00000113504 | NCBI 10723

Details for: SLC12A7

Gene ID: 10723

Symbol: SLC12A7

Ensembl ID: ENSG00000113504

Description: solute carrier family 12 member 7

Associated with

Cation-coupled chloride cotransporters
(R-HSA-426117)
Slc-mediated transmembrane transport
(R-HSA-425407)
Transport of inorganic cations/anions and amino acids/oligopeptides
(R-HSA-425393)
Transport of small molecules
(R-HSA-382551)
Ammonium import across plasma membrane
(GO:0140157)
Ammonium transmembrane transporter activity
(GO:0008519)
Cellular response to glucose stimulus
(GO:0071333)
Cell volume homeostasis
(GO:0006884)
Chemical synaptic transmission
(GO:0007268)
Chloride ion homeostasis
(GO:0055064)
Chloride transmembrane transport
(GO:1902476)
Monoatomic ion transport
(GO:0006811)
Plasma membrane
(GO:0005886)
Potassium:chloride symporter activity
(GO:0015379)
Potassium ion homeostasis
(GO:0055075)
Potassium ion import across plasma membrane
(GO:1990573)
Potassium ion transmembrane transport
(GO:0071805)
Protein-containing complex
(GO:0032991)
Protein kinase binding
(GO:0019901)
Synapse
(GO:0045202)

Other Information

Proteins

Solute carrier family 12 member 7

Genular Protein ID: 4244800525

Symbol: S12A7_HUMAN

Name: Solute carrier family 12 member 7

UniProtKB Accession Codes:

Q9Y666 A6NDS8 Q4G0F3 Q96I81 Q9H7I3 Q9H7I7 Q9UFW2

Database IDs:

Citations:

PubMed ID: 10347194

Title: Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family.

PubMed ID: 10347194

DOI: 10.1074/jbc.274.23.16355

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11214971

Title: Characterization of long cDNA clones from human adult spleen.

PubMed ID: 11214971

DOI: 10.1093/dnares/7.6.357

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 10913127

Title: Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4.

PubMed ID: 10913127

DOI: 10.1074/jbc.m003112200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21613606

Title: Similar Effects of all WNK3 Variants upon SLC12 Cotransporters.

PubMed ID: 21613606

DOI: 10.1152/ajpcell.00070.2011

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

Length: 1083
Mass: 119106
Checksum: BF50134614BF6617
Sequence:

MPTNFTVVPV EAHADGGGDE TAERTEAPGT PEGPEPERPS PGDGNPRENS PFLNNVEVEQ 
ESFFEGKNMA LFEEEMDSNP MVSSLLNKLA NYTNLSQGVV EHEEDEESRR REAKAPRMGT 
FIGVYLPCLQ NILGVILFLR LTWIVGVAGV LESFLIVAMC CTCTMLTAIS MSAIATNGVV 
PAGGSYYMIS RSLGPEFGGA VGLCFYLGTT FAGAMYILGT IEIFLTYISP GAAIFQAEAA 
GGEAAAMLHN MRVYGTCTLV LMALVVFVGV KYVNKLALVF LACVVLSILA IYAGVIKSAF 
DPPDIPVCLL GNRTLSRRSF DACVKAYGIH NNSATSALWG LFCNGSQPSA ACDEYFIQNN 
VTEIQGIPGA ASGVFLENLW STYAHAGAFV EKKGVPSVPV AEESRASALP YVLTDIAASF 
TLLVGIYFPS VTGIMAGSNR SGDLKDAQKS IPTGTILAIV TTSFIYLSCI VLFGACIEGV 
VLRDKFGEAL QGNLVIGMLA WPSPWVIVIG SFFSTCGAGL QSLTGAPRLL QAIARDGIVP 
FLQVFGHGKA NGEPTWALLL TVLICETGIL IASLDSVAPI LSMFFLMCYL FVNLACAVQT 
LLRTPNWRPR FKFYHWTLSF LGMSLCLALM FICSWYYALS AMLIAGCIYK YIEYRGAEKE 
WGDGIRGLSL NAARYALLRV EHGPPHTKNW RPQVLVMLNL DAEQAVKHPR LLSFTSQLKA 
GKGLTIVGSV LEGTYLDKHM EAQRAEENIR SLMSTEKTKG FCQLVVSSSL RDGMSHLIQS 
AGLGGLKHNT VLMAWPASWK QEDNPFSWKN FVDTVRDTTA AHQALLVAKN VDSFPQNQER 
FGGGHIDVWW IVHDGGMLML LPFLLRQHKV WRKCRMRIFT VAQVDDNSIQ MKKDLQMFLY 
HLRISAEVEV VEMVENDISA FTYERTLMME QRSQMLKQMQ LSKNEQEREA QLIHDRNTAS 
HTAAAARTQA PPTPDKVQMT WTREKLIAEK YRSRDTSLSG FKDLFSMKPD QSNVRRMHTA 
VKLNGVVLNK SQDAQLVLLN MPGPPKNRQG DENYMEFLEV LTEGLNRVLL VRGGGREVIT 
IYS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: SLC12A7

Associated with

Other Information

Cloning and characterization of KCC3 and KCC4, new members of the cation-chloride cotransporter gene family. PubMed ID: 10347194

The DNA sequence and comparative analysis of human chromosome 5. PubMed ID: 15372022

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Characterization of long cDNA clones from human adult spleen. PubMed ID: 11214971

The full-ORF clone resource of the German cDNA consortium. PubMed ID: 17974005

Functional comparison of the K+-Cl- cotransporters KCC1 and KCC4. PubMed ID: 10913127

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Similar Effects of all WNK3 Variants upon SLC12 Cotransporters. PubMed ID: 21613606

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569