Details for: OGA

Gene ID: 10724

Symbol: OGA

Ensembl ID: ENSG00000198408

Description: O-GlcNAcase

Associated with

  • Beta-n-acetylglucosaminidase activity
    (GO:0016231)
  • Cytosol
    (GO:0005829)
  • Glycoprotein catabolic process
    (GO:0006516)
  • Glycoprotein metabolic process
    (GO:0009100)
  • Hyalurononglucosaminidase activity
    (GO:0004415)
  • Identical protein binding
    (GO:0042802)
  • Membrane
    (GO:0016020)
  • N-acetylglucosamine metabolic process
    (GO:0006044)
  • Nucleus
    (GO:0005634)
  • Protein deglycosylation
    (GO:0006517)
  • Protein o-linked glycosylation
    (GO:0006493)
  • [protein]-3-o-(n-acetyl-d-glucosaminyl)-l-serine/l-threonine o-n-acetyl-alpha-d-glucosaminase activity
    (GO:0102571)
  • [protein]-3-o-(n-acetyl-d-glucosaminyl)-l-serine o-n-acetyl-alpha-d-glucosaminase activity
    (GO:0102167)
  • [protein]-3-o-(n-acetyl-d-glucosaminyl)-l-threonine o-n-acetyl-alpha-d-glucosaminase activity
    (GO:0102166)

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 5.88
    Marker Score: 78,153
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 5.2
    Marker Score: 2,524
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 2.86
    Marker Score: 6,272
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.85
    Marker Score: 11,918
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.69
    Marker Score: 1,502
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.68
    Marker Score: 1,561
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.56
    Marker Score: 54,636
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.55
    Marker Score: 807
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.47
    Marker Score: 2,838
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.43
    Marker Score: 2,228
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.42
    Marker Score: 11,177
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.36
    Marker Score: 2,943
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 2.36
    Marker Score: 3,176
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.33
    Marker Score: 2,578
  • Cell Name: follicular B cell (CL0000843)
    Fold Change: 2.33
    Marker Score: 2,525
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.28
    Marker Score: 1,729
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.28
    Marker Score: 1,331
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.27
    Marker Score: 33,976
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 2.24
    Marker Score: 2,713
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.23
    Marker Score: 1,892
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.23
    Marker Score: 84,552
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.21
    Marker Score: 4,258
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.21
    Marker Score: 9,159
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.21
    Marker Score: 81,410
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.2
    Marker Score: 43,802
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.2
    Marker Score: 697
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.17
    Marker Score: 634
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.16
    Marker Score: 8,988
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.15
    Marker Score: 2,046
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.13
    Marker Score: 1,416
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.09
    Marker Score: 7,416
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: 2.09
    Marker Score: 1,090
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.08
    Marker Score: 15,928
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.06
    Marker Score: 861
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 2.05
    Marker Score: 750
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.02
    Marker Score: 5,777
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.01
    Marker Score: 1,980
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 2.01
    Marker Score: 1,790
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2
    Marker Score: 2,156
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 1.96
    Marker Score: 1,179
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.95
    Marker Score: 7,555
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.95
    Marker Score: 1,304
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.94
    Marker Score: 2,202
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.94
    Marker Score: 837
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.92
    Marker Score: 118,379
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.91
    Marker Score: 18,001
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.89
    Marker Score: 3,180
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.88
    Marker Score: 1,125
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 1.88
    Marker Score: 1,282
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.87
    Marker Score: 19,295
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.86
    Marker Score: 1,226
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 1.86
    Marker Score: 657
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.86
    Marker Score: 4,559
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.85
    Marker Score: 936
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.84
    Marker Score: 681
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.83
    Marker Score: 994
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.81
    Marker Score: 40,555
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 1.81
    Marker Score: 965
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 1.81
    Marker Score: 1,008
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.81
    Marker Score: 17,163
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.8
    Marker Score: 429
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 1.78
    Marker Score: 3,735
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 1.77
    Marker Score: 717
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.76
    Marker Score: 15,080
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.75
    Marker Score: 4,688
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 1.73
    Marker Score: 599
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.72
    Marker Score: 2,376
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.72
    Marker Score: 15,112
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.72
    Marker Score: 1,301
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.71
    Marker Score: 494
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 1.71
    Marker Score: 436
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 1.71
    Marker Score: 1,812
  • Cell Name: naive B cell (CL0000788)
    Fold Change: 1.7
    Marker Score: 1,521
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.7
    Marker Score: 1,639
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.69
    Marker Score: 1,305
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.69
    Marker Score: 986
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.69
    Marker Score: 4,265
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.69
    Marker Score: 5,985
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.68
    Marker Score: 1,572
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.68
    Marker Score: 2,372
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.68
    Marker Score: 731
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.67
    Marker Score: 1,478
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.66
    Marker Score: 875
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.66
    Marker Score: 923
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.65
    Marker Score: 4,632
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.65
    Marker Score: 1,146
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.65
    Marker Score: 966
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.64
    Marker Score: 1,123
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.64
    Marker Score: 597
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.64
    Marker Score: 814
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.62
    Marker Score: 444
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 1.62
    Marker Score: 478
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.62
    Marker Score: 3,423
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.62
    Marker Score: 564
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 1.6
    Marker Score: 2,791
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.6
    Marker Score: 1,659
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.59
    Marker Score: 6,478
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.59
    Marker Score: 1,669
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.58
    Marker Score: 2,801
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.57
    Marker Score: 3,196

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Specificity:** O-GlcNAcase has a high specificity for O-GlcNAc-containing proteins, allowing it to target specific proteins for deglycosylation. 2. **Enzyme Activity:** O-GlcNAcase possesses beta-n-acetylhexosaminidase activity, which enables it to remove O-GlcNAc from proteins. 3. **Cellular Expression:** O-GlcNAcase is widely expressed in various cell types, including cardiac muscle cells, astrocytes, and smooth muscle cells. 4. **Regulation:** O-GlcNAcase activity is regulated by various signaling pathways, including the PI3K/AKT and MAPK/ERK pathways. **Pathways and Functions:** 1. **Glycoprotein Catabolic Process:** O-GlcNAcase plays a crucial role in the catabolism of glycoproteins, breaking down O-GlcNAc-containing proteins into smaller peptides. 2. **Glycoprotein Metabolic Process:** O-GlcNAcase is involved in the regulation of glycoprotein metabolism, influencing protein stability, folding, and activity. 3. **Cell Signaling:** O-GlcNAcase modulates cell signaling pathways, including the PI3K/AKT and MAPK/ERK pathways, by regulating the availability of O-GlcNAc-containing proteins. 4. **Cell Death and Survival:** O-GlcNAcase has been implicated in the regulation of cell death and survival, with altered activity leading to changes in cellular behavior. **Clinical Significance:** 1. **Disease Association:** Abnormal O-GlcNAcase activity has been linked to various diseases, including diabetes, cancer, and neurodegenerative disorders. 2. **Therapeutic Potential:** Targeting O-GlcNAcase activity has been proposed as a potential therapeutic strategy for treating diseases associated with altered glycosylation. 3. **Cancer Research:** O-GlcNAcase has been shown to play a role in cancer progression and metastasis, highlighting its potential as a biomarker and therapeutic target. 4. **Neurological Disorders:** O-GlcNAcase has been implicated in the regulation of neuronal function and survival, making it a potential target for the treatment of neurological disorders. In conclusion, O-GlcNAcase is a critical enzyme involved in the regulation of glycosylation in cells. Its specific activity, cellular expression, and regulation by various signaling pathways highlight its importance in maintaining cellular homeostasis. The clinical significance of O-GlcNAcase has been established in various diseases, and its potential as a therapeutic target has been proposed. Further research is needed to fully understand the mechanisms of O-GlcNAcase and its role in human health and disease.

Genular Protein ID: 1671292993

Symbol: OGA_HUMAN

Name: Beta-N-acetylhexosaminidase

UniProtKB Accession Codes:

O60502 B7WPB9 D3DR79 E9PGF9 O75166 Q86WV0 Q8IV98 Q9BVA5 Q9HAR0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 2 CPTAC 1 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 EC 2 EMBL 10 EMDB 1 EPD 1 Ensembl 4 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 2 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 30 PDBsum 21 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 2 Rhea 6 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 3 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9811929

Title: Novel immunogenic antigen homologous to hyaluronidase in meningioma.

PubMed ID: 9811929

DOI: 10.1093/hmg/7.12.1859

PubMed ID: 11341771

Title: Identification of a nuclear variant of MGEA5, a cytoplasmic hyaluronidase and a beta-N-acetylglucosaminidase.

PubMed ID: 11341771

DOI: 10.1006/bbrc.2001.4815

PubMed ID: 11148210

Title: Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain.

PubMed ID: 11148210

DOI: 10.1074/jbc.m010420200

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11788610

Title: Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic beta-N-acetylglucosaminidase, O-GlcNAcase.

PubMed ID: 11788610

DOI: 10.1074/jbc.m109656200

PubMed ID: 16533067

Title: Identification of Asp174 and Asp175 as the key catalytic residues of human O-GlcNAcase by functional analysis of site-directed mutants.

PubMed ID: 16533067

DOI: 10.1021/bi052370b

PubMed ID: 18586680

Title: Characterization of beta-N-acetylglucosaminidase cleavage by caspase-3 during apoptosis.

PubMed ID: 18586680

DOI: 10.1074/jbc.m804116200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20863279

Title: Human OGA binds substrates in a conserved peptide recognition groove.

PubMed ID: 20863279

DOI: 10.1042/bj20101338

PubMed ID: 20673219

Title: Isoforms of human O-GlcNAcase show distinct catalytic efficiencies.

PubMed ID: 20673219

DOI: 10.1134/s0006297910070175

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24088714

Title: Structure of a bacterial putative acetyltransferase defines the fold of the human O-GlcNAcase C-terminal domain.

PubMed ID: 24088714

DOI: 10.1098/rsob.130021

PubMed ID: 28742148

Title: Hijacking of the O-GlcNAcZYME complex by the HTLV-1 Tax oncoprotein facilitates viral transcription.

PubMed ID: 28742148

DOI: 10.1371/journal.ppat.1006518

PubMed ID: 22365600

Title: Synergy of peptide and sugar in O-GlcNAcase substrate recognition.

PubMed ID: 22365600

DOI: 10.1016/j.chembiol.2012.01.011

Sequence Information:

  • Length: 916
  • Mass: 102915
  • Checksum: 01F8A64A9B1475C6
  • Sequence:
    • MVQKESQATL EERESELSSN PAASAGASLE PPAAPAPGED NPAGAGGAAV AGAAGGARRF 
LCGVVEGFYG RPWVMEQRKE LFRRLQKWEL NTYLYAPKDD YKHRMFWREM YSVEEAEQLM 
TLISAAREYE IEFIYAISPG LDITFSNPKE VSTLKRKLDQ VSQFGCRSFA LLFDDIDHNM 
CAADKEVFSS FAHAQVSITN EIYQYLGEPE TFLFCPTEYC GTFCYPNVSQ SPYLRTVGEK 
LLPGIEVLWT GPKVVSKEIP VESIEEVSKI IKRAPVIWDN IHANDYDQKR LFLGPYKGRS 
TELIPRLKGV LTNPNCEFEA NYVAIHTLAT WYKSNMNGVR KDVVMTDSED STVSIQIKLE 
NEGSDEDIET DVLYSPQMAL KLALTEWLQE FGVPHQYSSR QVAHSGAKAS VVDGTPLVAA 
PSLNATTVVT TVYQEPIMSQ GAALSGEPTT LTKEEEKKQP DEEPMDMVVE KQEETDHKND 
NQILSEIVEA KMAEELKPMD TDKESIAESK SPEMSMQEDC ISDIAPMQTD EQTNKEQFVP 
GPNEKPLYTA EPVTLEDLQL LADLFYLPYE HGPKGAQMLR EFQWLRANSS VVSVNCKGKD 
SEKIEEWRSR AAKFEEMCGL VMGMFTRLSN CANRTILYDM YSYVWDIKSI MSMVKSFVQW 
LGCRSHSSAQ FLIGDQEPWA FRGGLAGEFQ RLLPIDGAND LFFQPPPLTP TSKVYTIRPY 
FPKDEASVYK ICREMYDDGV GLPFQSQPDL IGDKLVGGLL SLSLDYCFVL EDEDGICGYA 
LGTVDVTPFI KKCKISWIPF MQEKYTKPNG DKELSEAEKI MLSFHEEQEV LPETFLANFP 
SLIKMDIHKK VTDPSVAKSM MACLLSSLKA NGSRGAFCEV RPDDKRILEF YSKLGCFEIA 
KMEGFPKDVV ILGRSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.