Details for: NFAT5

Gene ID: 10725

Symbol: NFAT5

Ensembl ID: ENSG00000102908

Description: nuclear factor of activated T cells 5

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 5.84
    Marker Score: 4,793
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 4.87
    Marker Score: 20,319
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.8
    Marker Score: 85,218
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 4.42
    Marker Score: 3,815
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 4.14
    Marker Score: 3,673
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 3.9
    Marker Score: 7,509
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.7
    Marker Score: 4,976
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 3.42
    Marker Score: 2,251
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 3.37
    Marker Score: 2,597
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 3.36
    Marker Score: 4,062
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 3.35
    Marker Score: 13,952
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 3.32
    Marker Score: 3,757
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.28
    Marker Score: 10,750
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.21
    Marker Score: 2,228
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.13
    Marker Score: 6,874
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 3.09
    Marker Score: 66,006
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 3.08
    Marker Score: 12,905
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.95
    Marker Score: 65,911
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 2.93
    Marker Score: 1,546
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 2.92
    Marker Score: 2,788
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 2.92
    Marker Score: 7,316
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.92
    Marker Score: 3,358
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.81
    Marker Score: 1,563
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.76
    Marker Score: 93,120
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 2.74
    Marker Score: 2,956
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 2.65
    Marker Score: 764
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.58
    Marker Score: 11,949
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 2.56
    Marker Score: 13,772
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.55
    Marker Score: 1,487
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.52
    Marker Score: 737
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 2.52
    Marker Score: 796
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 2.52
    Marker Score: 1,364
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.49
    Marker Score: 1,488
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.49
    Marker Score: 37,215
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.48
    Marker Score: 39,868
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.47
    Marker Score: 2,605
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.46
    Marker Score: 18,881
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 2.43
    Marker Score: 2,936
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.42
    Marker Score: 92,010
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 2.42
    Marker Score: 1,194
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.41
    Marker Score: 47,898
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.38
    Marker Score: 2,970
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.38
    Marker Score: 1,394
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.33
    Marker Score: 9,639
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 2.31
    Marker Score: 5,535
  • Cell Name: fat cell (CL0000136)
    Fold Change: 2.28
    Marker Score: 1,272
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 2.27
    Marker Score: 825
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.25
    Marker Score: 1,479
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.23
    Marker Score: 82,237
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 2.19
    Marker Score: 1,462
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 2.19
    Marker Score: 1,894
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.18
    Marker Score: 806
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 2.15
    Marker Score: 7,206
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 2.14
    Marker Score: 3,113
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.12
    Marker Score: 8,208
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.07
    Marker Score: 2,287
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.06
    Marker Score: 19,397
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.03
    Marker Score: 5,801
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.02
    Marker Score: 124,154
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 2.01
    Marker Score: 512
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.01
    Marker Score: 4,612
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.99
    Marker Score: 2,019
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.99
    Marker Score: 832
  • Cell Name: granule cell (CL0000120)
    Fold Change: 1.98
    Marker Score: 14,950
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.98
    Marker Score: 4,863
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 1.97
    Marker Score: 981
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.95
    Marker Score: 705
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.95
    Marker Score: 1,375
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.94
    Marker Score: 3,391
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.91
    Marker Score: 990
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.9
    Marker Score: 2,696
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 1.9
    Marker Score: 2,031
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 1.89
    Marker Score: 957
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.89
    Marker Score: 19,489
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.89
    Marker Score: 489
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.88
    Marker Score: 6,672
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.87
    Marker Score: 684
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.87
    Marker Score: 17,775
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 1.87
    Marker Score: 9,800
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.86
    Marker Score: 904
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.85
    Marker Score: 7,545
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.85
    Marker Score: 2,287
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.85
    Marker Score: 3,100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.83
    Marker Score: 15,703
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.82
    Marker Score: 6,467
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.82
    Marker Score: 4,581
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.81
    Marker Score: 3,614
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.8
    Marker Score: 594
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.8
    Marker Score: 61,111
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.79
    Marker Score: 671
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 1.79
    Marker Score: 2,524
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.76
    Marker Score: 600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.74
    Marker Score: 2,557
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.73
    Marker Score: 1,306
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.7
    Marker Score: 1,825
  • Cell Name: basal cell (CL0000646)
    Fold Change: 1.67
    Marker Score: 2,159
  • Cell Name: club cell (CL0000158)
    Fold Change: 1.64
    Marker Score: 1,919
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.6
    Marker Score: 11,901
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.59
    Marker Score: 320
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 1.58
    Marker Score: 502

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NFAT5 is a transcription factor that belongs to the NFAT family of proteins. It is characterized by its ability to regulate gene expression in response to various stimuli, including osmotic stress, cytokines, and DNA damage. NFAT5 exhibits: 1. **Sequence-specific DNA binding activity**: NFAT5 binds to specific DNA sequences, regulating gene expression. 2. **Calcineurin-NFAT signaling cascade regulation**: NFAT5 is involved in the regulation of the calcineurin-NFAT signaling pathway, which is crucial for various cellular processes. 3. **Osmotic stress response**: NFAT5 is activated in response to hyperosmotic conditions, allowing cells to adapt to changing osmotic environments. 4. **Cytokine production regulation**: NFAT5 regulates cytokine production, which is essential for immune responses and inflammation. 5. **Dysregulation in disease**: NFAT5 dysregulation has been implicated in various diseases, including kidney damage, cancer, and neurological disorders. **Pathways and Functions** NFAT5 is involved in various signaling pathways, including: 1. **Calcineurin-NFAT signaling cascade**: NFAT5 regulates the activity of calcineurin, a phosphatase that dephosphorylates and activates NFAT proteins. 2. **Cellular hyperosmotic response**: NFAT5 is activated in response to hyperosmotic conditions, allowing cells to adapt to changing osmotic environments. 3. **Cytokine production**: NFAT5 regulates cytokine production, which is essential for immune responses and inflammation. 4. **Gene expression regulation**: NFAT5 regulates gene expression by binding to specific DNA sequences. 5. **DNA damage response**: NFAT5 is involved in the regulation of DNA damage response pathways. **Clinical Significance** NFAT5 dysregulation has been implicated in various diseases, including: 1. **Kidney damage**: NFAT5 dysregulation has been associated with kidney damage and fibrosis. 2. **Cancer**: NFAT5 has been implicated in the development and progression of various cancers, including renal and breast cancer. 3. **Neurological disorders**: NFAT5 dysregulation has been associated with neurological disorders, including Alzheimer's disease and Parkinson's disease. 4. **Osteoporosis**: NFAT5 has been implicated in the regulation of osteoclast activity, which is essential for bone resorption. 5. **Inflammatory diseases**: NFAT5 regulates cytokine production, which is essential for immune responses and inflammation. In conclusion, NFAT5 is a transcription factor that plays a crucial role in various cellular processes, including osmotic stress response, cytokine production, and gene expression regulation. Its dysregulation has been implicated in various diseases, highlighting the importance of NFAT5 in maintaining cellular homeostasis and preventing disease.

Genular Protein ID: 577988347

Symbol: NFAT5_HUMAN

Name: Nuclear factor of activated T-cells 5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10051678

Title: Tonicity-responsive enhancer binding protein, a rel-like protein that stimulates transcription in response to hypertonicity.

PubMed ID: 10051678

DOI: 10.1073/pnas.96.5.2538

PubMed ID: 10377394

Title: NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun.

PubMed ID: 10377394

DOI: 10.1073/pnas.96.13.7214

PubMed ID: 11528118

Title: Genomic organization of the human NFAT5 gene: exon-intron structure of the 14-kb transcript and CpG-island analysis of the promoter region.

PubMed ID: 11528118

DOI: 10.1159/000056990

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11233530

Title: NFAT5: the NF-AT family of transcription factors expands in a new direction.

PubMed ID: 11233530

DOI: 10.1101/sqb.1999.64.517

PubMed ID: 10565538

Title: Isolation and characterization of novel CAG repeat containing genes expressed in human brain.

PubMed ID: 10565538

DOI: 10.3109/10425179909033929

PubMed ID: 11934689

Title: Mouse TonEBP-NFAT5: expression in early development and alternative splicing.

PubMed ID: 11934689

DOI: 10.1152/ajprenal.00123.2001

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21209322

Title: High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization.

PubMed ID: 21209322

DOI: 10.1091/mbc.e10-08-0681

PubMed ID: 22266867

Title: Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.

PubMed ID: 22266867

DOI: 10.1038/onc.2011.618

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25772364

Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.

PubMed ID: 25772364

DOI: 10.1016/j.celrep.2015.02.033

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 34049076

Title: PARP1-mediated PARylation of TonEBP prevents R-loop-associated DNA damage.

PubMed ID: 34049076

DOI: 10.1016/j.dnarep.2021.103132

PubMed ID: 11780147

Title: Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor.

PubMed ID: 11780147

DOI: 10.1038/nsb749

Sequence Information:

  • Length: 1531
  • Mass: 165763
  • Checksum: A68C68088DABF69E
  • Sequence:
  • MPSDFISLLS ADLDLESPKS LYSRESVYDL LPKELQLPPS RETSVASMSQ TSGGEAGSPP 
    PAVVAADASS APSSSSMGGA CSSFTTSSSP TIYSTSVTDS KAMQVESCSS AVGVSNRGVS 
    EKQLTSNTVQ QHPSTPKRHT VLYISPPPED LLDNSRMSCQ DEGCGLESEQ SCSMWMEDSP 
    SNFSNMSTSS YNDNTEVPRK SRKRNPKQRP GVKRRDCEES NMDIFDADSA KAPHYVLSQL 
    TTDNKGNSKA GNGTLENQKG TGVKKSPMLC GQYPVKSEGK ELKIVVQPET QHRARYLTEG 
    SRGSVKDRTQ QGFPTVKLEG HNEPVVLQVF VGNDSGRVKP HGFYQACRVT GRNTTPCKEV 
    DIEGTTVIEV GLDPSNNMTL AVDCVGILKL RNADVEARIG IAGSKKKSTR ARLVFRVNIM 
    RKDGSTLTLQ TPSSPILCTQ PAGVPEILKK SLHSCSVKGE EEVFLIGKNF LKGTKVIFQE 
    NVSDENSWKS EAEIDMELFH QNHLIVKVPP YHDQHITLPV SVGIYVVTNA GRSHDVQPFT 
    YTPDPAAAGA LNVNVKKEIS SPARPCSFEE AMKAMKTTGC NLDKVNIIPN ALMTPLIPSS 
    MIKSEDVTPM EVTAEKRSST IFKTTKSVGS TQQTLENISN IAGNGSFSSP SSSHLPSENE 
    KQQQIQPKAY NPETLTTIQT QDISQPGTFP AVSASSQLPN SDALLQQATQ FQTRETQSRE 
    ILQSDGTVVN LSQLTEASQQ QQQSPLQEQA QTLQQQISSN IFPSPNSVSQ LQNTIQQLQA 
    GSFTGSTASG SSGSVDLVQQ VLEAQQQLSS VLFSAPDGNE NVQEQLSADI FQQVSQIQSG 
    VSPGMFSSTE PTVHTRPDNL LPGRAESVHP QSENTLSNQQ QQQQQQQQVM ESSAAMVMEM 
    QQSICQAAAQ IQSELFPSTA SANGNLQQSP VYQQTSHMMS ALSTNEDMQM QCELFSSPPA 
    VSGNETSTTT TQQVATPGTT MFQTSSSGDG EETGTQAKQI QNSVFQTMVQ MQHSGDNQPQ 
    VNLFSSTKSM MSVQNSGTQQ QGNGLFQQGN EMMSLQSGNF LQQSSHSQAQ LFHPQNPIAD 
    AQNLSQETQG SLFHSPNPIV HSQTSTTSSE QMQPPMFHSQ STIAVLQGSS VPQDQQSTNI 
    FLSQSPMNNL QTNTVAQEAF FAAPNSISPL QSTSNSEQQA AFQQQAPISH IQTPMLSQEQ 
    AQPPQQGLFQ PQVALGSLPP NPMPQSQQGT MFQSQHSIVA MQSNSPSQEQ QQQQQQQQQQ 
    QQQQQQSILF SNQNTMATMA SPKQPPPNMI FNPNQNPMAN QEQQNQSIFH QQSNMAPMNQ 
    EQQPMQFQSQ STVSSLQNPG PTQSESSQTP LFHSSPQIQL VQGSPSSQEQ QVTLFLSPAS 
    MSALQTSINQ QDMQQSPLYS PQNNMPGIQG ATSSPQPQAT LFHNTAGGTM NQLQNSPGSS 
    QQTSGMFLFG IQNNCSQLLT SGPATLPDQL MAISQPGQPQ NEGQPPVTTL LSQQMPENSP 
    LASSINTNQN IEKIDLLVSL QNQGNNLTGS F

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.