NUDC | ENSG00000090273 | NCBI 10726

Details for: NUDC

Gene ID: 10726

Symbol: NUDC

Ensembl ID: ENSG00000090273

Description: nuclear distribution C, dynein complex regulator

Associated with

Amplification of signal from the kinetochores
(R-HSA-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-HSA-141444)
Cell cycle
(R-HSA-1640170)
Cell cycle, mitotic
(R-HSA-69278)
Cell cycle checkpoints
(R-HSA-69620)
Eml4 and nudc in mitotic spindle formation
(R-HSA-9648025)
Mitotic anaphase
(R-HSA-68882)
Mitotic metaphase and anaphase
(R-HSA-2555396)
Mitotic prometaphase
(R-HSA-68877)
Mitotic spindle checkpoint
(R-HSA-69618)
M phase
(R-HSA-68886)
Resolution of sister chromatid cohesion
(R-HSA-2500257)
Rho gtpase cycle
(R-HSA-9012999)
Rho gtpase effectors
(R-HSA-195258)
Rho gtpases activate formins
(R-HSA-5663220)
Rnd2 gtpase cycle
(R-HSA-9696270)
Separation of sister chromatids
(R-HSA-2467813)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Cadherin binding
(GO:0045296)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Microtubule
(GO:0005874)
Midbody
(GO:0030496)
Mitotic metaphase chromosome alignment
(GO:0007080)
Mitotic spindle
(GO:0072686)
Mitotic spindle organization
(GO:0007052)
Nuclear migration
(GO:0007097)
Nucleoplasm
(GO:0005654)
Protein binding
(GO:0005515)
Protein folding
(GO:0006457)
Response to peptide hormone
(GO:0043434)
Spindle
(GO:0005819)
Unfolded protein binding
(GO:0051082)

Other Information

Proteins

Nuclear migration protein nudC

Genular Protein ID: 2857680593

Symbol: NUDC_HUMAN

Name: Nuclear migration protein nudC

UniProtKB Accession Codes:

Q9Y266 Q5QP31 Q5QP35 Q9H0N2 Q9Y2B6

Database IDs:

Citations:

PubMed ID: 10210332

Title: A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis.

PubMed ID: 10210332

DOI: 10.1016/s0301-472x(98)00074-5

PubMed ID: 10453739

Title: Molecular cloning and characterization of the human NUDC gene.

PubMed ID: 10453739

DOI: 10.1007/s004390050994

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12852857

Title: A role for Plk1 phosphorylation of NudC in cytokinesis.

PubMed ID: 12852857

DOI: 10.1016/s1534-5807(03)00186-2

PubMed ID: 12679384

Title: Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis.

PubMed ID: 12679384

DOI: 10.1242/jcs.00412

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22159412

Title: Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein.

PubMed ID: 22159412

DOI: 10.1242/jcs.085407

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25789526

Title: EML4 promotes the loading of NUDC to the spindle for mitotic progression.

PubMed ID: 25789526

DOI: 10.1080/15384101.2015.1026514

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

Length: 331
Mass: 38243
Checksum: 34F591170F7594AF
Sequence:

MGGEQEEERF DGMLLAMAQQ HEGGVQELVN TFFSFLRRKT DFFIGGEEGM AEKLITQTFS 
HHNQLAQKTR REKRARQEAE RREKAERAAR LAKEAKSETS GPQIKELTDE EAERLQLEID 
QKKDAENHEA QLKNGSLDSP GKQDTEEDEE EDEKDKGKLK PNLGNGADLP NYRWTQTLSE 
LDLAVPFCVN FRLKGKDMVV DIQRRHLRVG LKGQPAIIDG ELYNEVKVEE SSWLIEDGKV 
VTVHLEKINK MEWWSRLVSS DPEINTKKIN PENSKLSDLD SETRSMVEKM MYDQRQKSMG 
LPTSDEQKKQ EILKKFMDQH PEMDFSKAKF N

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: NUDC

Associated with

Other Information

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis. PubMed ID: 10210332

Molecular cloning and characterization of the human NUDC gene. PubMed ID: 10453739

Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. PubMed ID: 11230166

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A role for Plk1 phosphorylation of NudC in cytokinesis. PubMed ID: 12852857

Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. PubMed ID: 12679384

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. PubMed ID: 19413330

Lysine acetylation targets protein complexes and co-regulates major cellular functions. PubMed ID: 19608861

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein. PubMed ID: 22159412

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

EML4 promotes the loading of NUDC to the spindle for mitotic progression. PubMed ID: 25789526

N-terminome analysis of the human mitochondrial proteome. PubMed ID: 25944712