Details for: PTGES3

Gene ID: 10728

Symbol: PTGES3

Ensembl ID: ENSG00000110958

Description: prostaglandin E synthase 3

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.99
    Marker Score: 135,783
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 3.8
    Marker Score: 3,236
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.62
    Marker Score: 8,837
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 3.4
    Marker Score: 3,635
  • Cell Name: blood cell (CL0000081)
    Fold Change: 3.19
    Marker Score: 37,126
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 3.17
    Marker Score: 31,421
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 3.16
    Marker Score: 41,691
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 3.15
    Marker Score: 3,808
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 3.1
    Marker Score: 2,433
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 3.08
    Marker Score: 162,795
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: 3.06
    Marker Score: 1,275
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 3.03
    Marker Score: 2,862
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 3.02
    Marker Score: 3,153
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.99
    Marker Score: 103,645
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 2.99
    Marker Score: 8,388
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 2.98
    Marker Score: 7,527
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 2.96
    Marker Score: 14,541
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.93
    Marker Score: 699
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.91
    Marker Score: 12,459
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 2.9
    Marker Score: 1,810
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 2.87
    Marker Score: 2,265
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.86
    Marker Score: 18,624
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 2.85
    Marker Score: 5,357
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.83
    Marker Score: 8,923
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 2.82
    Marker Score: 24,490
  • Cell Name: double negative T regulatory cell (CL0011024)
    Fold Change: 2.8
    Marker Score: 2,711
  • Cell Name: naive thymus-derived CD8-positive, alpha-beta T cell (CL0000900)
    Fold Change: 2.78
    Marker Score: 4,974
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 2.78
    Marker Score: 4,561
  • Cell Name: theca cell (CL0000503)
    Fold Change: 2.78
    Marker Score: 1,990
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.75
    Marker Score: 5,593
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.73
    Marker Score: 2,071
  • Cell Name: activated CD4-positive, alpha-beta T cell, human (CL0001043)
    Fold Change: 2.71
    Marker Score: 1,232
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.7
    Marker Score: 1,538
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.69
    Marker Score: 4,459
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 2.69
    Marker Score: 937
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.68
    Marker Score: 3,794
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 2.67
    Marker Score: 2,249
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 2.65
    Marker Score: 2,884
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 2.65
    Marker Score: 1,079
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 2.64
    Marker Score: 1,184
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 2.63
    Marker Score: 3,787
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 2.63
    Marker Score: 1,532
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 2.63
    Marker Score: 20,500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.61
    Marker Score: 9,274
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 2.6
    Marker Score: 1,368
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 2.59
    Marker Score: 1,295
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 2.59
    Marker Score: 3,031
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 2.58
    Marker Score: 1,955
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.57
    Marker Score: 5,377
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 2.57
    Marker Score: 1,730
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 2.56
    Marker Score: 2,750
  • Cell Name: B-1 B cell (CL0000819)
    Fold Change: 2.55
    Marker Score: 4,443
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.55
    Marker Score: 1,599
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.53
    Marker Score: 2,270
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 2.52
    Marker Score: 4,935
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 2.52
    Marker Score: 21,683
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.51
    Marker Score: 10,271
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 2.51
    Marker Score: 6,721
  • Cell Name: activated CD4-positive, alpha-beta T cell (CL0000896)
    Fold Change: 2.5
    Marker Score: 1,804
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 2.48
    Marker Score: 7,798
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 2.48
    Marker Score: 3,948
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 2.48
    Marker Score: 1,278
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 2.48
    Marker Score: 4,216
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.48
    Marker Score: 2,331
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.47
    Marker Score: 1,803
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 2.47
    Marker Score: 566
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 2.47
    Marker Score: 650
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.47
    Marker Score: 2,167
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 2.46
    Marker Score: 3,209
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.46
    Marker Score: 2,316
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.46
    Marker Score: 10,603
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 2.46
    Marker Score: 2,757
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.46
    Marker Score: 1,632
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.45
    Marker Score: 3,550
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 2.45
    Marker Score: 2,179
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.45
    Marker Score: 6,758
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 2.45
    Marker Score: 1,915
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.44
    Marker Score: 2,612
  • Cell Name: small pre-B-II cell (CL0000954)
    Fold Change: 2.44
    Marker Score: 2,934
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 2.44
    Marker Score: 1,158
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 2.43
    Marker Score: 2,278
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 2.43
    Marker Score: 2,468
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 2.43
    Marker Score: 2,998
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.42
    Marker Score: 4,843
  • Cell Name: basal cell (CL0000646)
    Fold Change: 2.42
    Marker Score: 3,128
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 2.42
    Marker Score: 980
  • Cell Name: CD8-positive, alpha-beta cytotoxic T cell (CL0000794)
    Fold Change: 2.41
    Marker Score: 2,128
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 2.41
    Marker Score: 4,269
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.4
    Marker Score: 9,266
  • Cell Name: naive thymus-derived CD4-positive, alpha-beta T cell (CL0000895)
    Fold Change: 2.4
    Marker Score: 4,119
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 2.4
    Marker Score: 1,405
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.4
    Marker Score: 6,521
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.39
    Marker Score: 26,936
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 2.39
    Marker Score: 2,822
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 2.39
    Marker Score: 849
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 2.39
    Marker Score: 678
  • Cell Name: eurydendroid cell (CL0000253)
    Fold Change: 2.39
    Marker Score: 974
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 2.38
    Marker Score: 831
  • Cell Name: fibroblast of connective tissue of prostate (CL1000299)
    Fold Change: 2.38
    Marker Score: 592
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 2.38
    Marker Score: 2,294

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PTGES3 exhibits several key characteristics that distinguish it from other prostaglandin E synthases. These include: * **Tissue-specific expression**: PTGES3 is primarily expressed in cells of the immune system, including T cells, NK T cells, and macrophages. * **Prostaglandin E synthase activity**: PTGES3 is responsible for the conversion of prostaglandin H2 to prostaglandin E2, a key step in the biosynthesis of prostaglandins. * **Involvement in immune response**: PTGES3 is involved in the regulation of immune responses, including the activation of T cells and the production of cytokines. * **Implication in disease**: PTGES3 has been implicated in various diseases, including cancer, inflammatory disorders, and infectious diseases. **Pathways and Functions** PTGES3 is involved in several key pathways, including: * **Arachidonic acid metabolism**: PTGES3 is a key enzyme in the biosynthesis of prostaglandins from arachidonic acid. * **Cyclooxygenase pathway**: PTGES3 is involved in the conversion of prostaglandin H2 to prostaglandin E2, a key step in the cyclooxygenase pathway. * **Signaling by nuclear receptors**: PTGES3 is involved in the regulation of signaling by nuclear receptors, including the glucocorticoid receptor. * **Telomerase activity**: PTGES3 has been implicated in the regulation of telomerase activity, a key process involved in cellular immortalization. **Clinical Significance** PTGES3 has significant clinical implications, including: * **Cancer**: PTGES3 has been implicated in the development and progression of various cancers, including prostate cancer and breast cancer. * **Inflammatory disorders**: PTGES3 is involved in the regulation of inflammatory responses, and its dysregulation has been implicated in various inflammatory disorders, including arthritis and asthma. * **Infectious diseases**: PTGES3 has been implicated in the regulation of immune responses to infectious diseases, including SARS-CoV and influenza. * **Prosthetic joint disease**: PTGES3 has been implicated in the development of prosthetic joint disease, a condition characterized by inflammation and wear and tear of prosthetic joints. In conclusion, PTGES3 is a critical enzyme involved in the biosynthesis of prostaglandins and plays significant roles in various physiological and pathological processes. Its dysregulation has been implicated in various diseases, including cancer, inflammatory disorders, and infectious diseases, highlighting the importance of PTGES3 as a potential therapeutic target.

Genular Protein ID: 928917070

Symbol: TEBP_HUMAN

Name: Prostaglandin E synthase 3

UniProtKB Accession Codes:

Q15185 A8K7D0 B4DHP2 B4DP11 B4DP21 Q8WU70

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChEBI 2 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 3 EC 1 ELM 1 EMBL 10 EMDB 5 EPD 1 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 4 PIR 1 PRIDE 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 8 RefSeq 6 Rhea 1 SABIO-RK 1 SAM 1 SASBDB 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8114727

Title: Characterization of a novel 23-kilodalton protein of unactive progesterone receptor complexes.

PubMed ID: 8114727

DOI: 10.1128/mcb.14.3.1956-1963.1994

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11274138

Title: Stable association of hsp90 and p23, but Not hsp70, with active human telomerase.

PubMed ID: 11274138

DOI: 10.1074/jbc.c100055200

PubMed ID: 12077419

Title: Disassembly of transcriptional regulatory complexes by molecular chaperones.

PubMed ID: 12077419

DOI: 10.1126/science.1073051

PubMed ID: 10922363

Title: Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis.

PubMed ID: 10922363

DOI: 10.1074/jbc.m003504200

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22451931

Title: Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis.

PubMed ID: 22451931

DOI: 10.1073/pnas.1200934109

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24711448

Title: Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing.

PubMed ID: 24711448

DOI: 10.1074/jbc.m113.541227

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27353360

Title: The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.

PubMed ID: 27353360

DOI: 10.1038/ncomms12037

PubMed ID: 28863261

Title: Characterization of Hsp90 co-chaperone p23 cleavage by caspase-7 uncovers a peptidase-substrate interaction involving intrinsically disordered regions.

PubMed ID: 28863261

DOI: 10.1021/acs.biochem.7b00298

PubMed ID: 29127155

Title: Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.

PubMed ID: 29127155

DOI: 10.15252/embj.201796700

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 10811660

Title: Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone.

PubMed ID: 10811660

DOI: 10.1074/jbc.m003410200

Sequence Information:

  • Length: 160
  • Mass: 18697
  • Checksum: 23538BB9D7AFD73F
  • Sequence:
    • MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID 
PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF 
DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE

Genular Protein ID: 1645611720

Symbol: A0A087WYT3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WYT3

Database IDs:

ARBA 14 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EC 1 EMBL 1 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 Rhea 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 UniPathway 1 VEuPathDB 1

Citations:

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 17487921

Title: Toward a global characterization of the phosphoproteome in prostate cancer cells: identification of phosphoproteins in the LNCaP cell line.

PubMed ID: 17487921

DOI: 10.1002/elps.200600782

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 164
  • Mass: 19155
  • Checksum: 6CBD3E481BE9E81A
  • Sequence:
    • MSLEKQPASA KWYDRRDYVF IEFCVEDSKD VNVNFEKSKL TFSCLGGSDN FKHLNEIDLF 
HCIDPNDSKH KRTDRSILCC LRKGESGQSW PRLTKERAKL NWLSVDFNNW KDWEDDSDED 
MSNFDRFSEM MNNMGGDEDV DLPEVDGADD DSQDSDDEKM PDLE

Genular Protein ID: 1980650312

Symbol: B3KUY2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KUY2

Database IDs:

ARBA 14 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 2 ChiTaRS 1 DNASU 1 EC 1 EMBL 4 GO 5 Gene3D 1 GenomeRNAi 1 IntAct 1 InterPro 3 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 1 RuleBase 1 SUPFAM 1 UniPathway 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 165
  • Mass: 19449
  • Checksum: 054C08D184610439
  • Sequence:
    • MFYLRQPASA KWYDRRDYVF IEFCVEDSKD VNVNFEKSKL TFSCLGGSDN FKHLNEIDLF 
HCIDPNDSKH KRTDRSILCC LRKGESGQSW PRLTKERAKL NWLSVDFNNW KDWEDDSDED 
MSNFDRFSEM MNNMGGDEDV DLPEVDGADD VSLKILFSVY FHTIK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.