Details for: STAG3

Gene ID: 10734

Symbol: STAG3

Ensembl ID: ENSG00000066923

Description: STAG3 cohesin complex component

Associated with

Other Information

Genular Protein ID: 3993355205

Symbol: STAG3_HUMAN

Name: Cohesin subunit SA-3

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10698974

Title: STAG3, a novel gene encoding a protein involved in meiotic chromosome pairing and location of STAG3-related genes flanking the Williams-Beuren syndrome deletion.

PubMed ID: 10698974

DOI: 10.1096/fasebj.14.3.581

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12034751

Title: STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis.

PubMed ID: 12034751

DOI: 10.1093/embo-reports/kvf108

PubMed ID: 22428046

Title: Genome-wide linkage in a highly consanguineous pedigree reveals two novel loci on chromosome 7 for non-syndromic familial Premature Ovarian Failure.

PubMed ID: 22428046

DOI: 10.1371/journal.pone.0033412

PubMed ID: 24597867

Title: Mutant cohesin in premature ovarian failure.

PubMed ID: 24597867

DOI: 10.1056/nejmoa1309635

PubMed ID: 31682730

Title: Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest.

PubMed ID: 31682730

DOI: 10.1093/humrep/dez204

PubMed ID: 30006057

Title: Two rare loss-of-function variants in the STAG3 gene leading to primary ovarian insufficiency.

PubMed ID: 30006057

DOI: 10.1016/j.ejmg.2018.07.008

PubMed ID: 32741963

Title: Genetic dissection of spermatogenic arrest through exome analysis: clinical implications for the management of azoospermic men.

PubMed ID: 32741963

DOI: 10.1038/s41436-020-0907-1

PubMed ID: 32634216

Title: STAG3 homozygous missense variant causes primary ovarian insufficiency and male non-obstructive azoospermia.

PubMed ID: 32634216

DOI: 10.1093/molehr/gaaa050

Sequence Information:

  • Length: 1225
  • Mass: 139034
  • Checksum: A29B2FC0C3CCE83D
  • Sequence:
  • MSSPLQRAVG DTKRALSASS SSSASLPFDD RDSNHTSEGN GDSLLADEDT DFEDSLNRNV 
    KKRAAKRPPK TTPVAKHPKK GSRVVHRHSR KQSEPPANDL FNAVKAAKSD MQSLVDEWLD 
    SYKQDQDAGF LELVNFFIQS CGCKGIVTPE MFKKMSNSEI IQHLTEQFNE DSGDYPLIAP 
    GPSWKKFQGS FCEFVRTLVC QCQYSLLYDG FPMDDLISLL TGLSDSQVRA FRHTSTLAAM 
    KLMTSLVKVA LQLSVHQDNN QRQYEAERNK GPGQRAPERL ESLLEKRKEL QEHQEEIEGM 
    MNALFRGVFV HRYRDVLPEI RAICIEEIGC WMQSYSTSFL TDSYLKYIGW TLHDKHREVR 
    LKCVKALKGL YGNRDLTTRL ELFTSRFKDR MVSMVMDREY DVAVEAVRLL ILILKNMEGV 
    LTDADCESVY PVVYASHRGL ASAAGEFLYW KLFYPECEIR MMGGREQRQS PGAQRTFFQL 
    LLSFFVESEL HDHAAYLVDS LWDCAGARLK DWEGLTSLLL EKDQNLGDVQ ESTLIEILVS 
    SARQASEGHP PVGRVTGRKG LTSKERKTQA DDRVKLTEHL IPLLPQLLAK FSADAEKVTP 
    LLQLLSCFDL HIYCTGRLEK HLELFLQQLQ EVVVKHAEPA VLEAGAHALY LLCNPEFTFF 
    SRADFARSQL VDLLTDRFQQ ELEELLQSSF LDEDEVYNLA ATLKRLSAFY NTHDLTRWEL 
    YEPCCQLLQK AVDTGEVPHQ VILPALTLVY FSILWTLTHI SKSDASQKQL SSLRDRMVAF 
    CELCQSCLSD VDTEIQEQAF VLLSDLLLIF SPQMIVGGRD FLRPLVFFPE ATLQSELASF 
    LMDHVFIQPG DLGSGDSQED HLQIERLHQR RRLLAGFCKL LLYGVLEMDA ASDVFKHYNK 
    FYNDYGDIIK ETLTRARQID RSHCSRILLL SLKQLYTELL QEHGPQGLNE LPAFIEMRDL 
    ARRFALSFGP QQLQNRDLVV MLHKEGIQFS LSELPPAGSS NQPPNLAFLE LLSEFSPRLF 
    HQDKQLLLSY LEKCLQHVSQ APGHPWGPVT TYCHSLSPVE NTAETSPQVL PSSKRRRVEG 
    PAKPNREDVS SSQEESLQLN SIPPTPTLTS TAVKSRQPLW GLKEMEEEDG SELDFAQGQP 
    VAGTERSRFL GPQYFQTPHN PSGPGLGNQL MRLSLMEEDE EEELEIQDES NEERQDTDMQ 
    ASSYSSTSER GLDLLDSTEL DIEDF

Genular Protein ID: 739726126

Symbol: D6W5U7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

Sequence Information:

  • Length: 1226
  • Mass: 139121
  • Checksum: CD9D2918AA685F41
  • Sequence:
  • MSSPLQRAVG DTKRALSASS SSSASLPFDD RDSNHTSEGN GDSLLADEDT DFEDSLNRNV 
    KKRAAKRPPK TTPVAKHPKK GSRVVHRHSR KQSEPPANDL FNAVKAAKSD MQSLVDEWLD 
    SYKQDQDAGF LELVNFFIQS CGCKGIVTPE MFKKMSNSEI IQHLTEQFNE DSGDYPLIAP 
    GPSWKKFQGS FCEFVRTLVC QCQYSLLYDG FPMDDLISLL TGLSDSQVRA FRHTSTLAAM 
    KLMTSLVKVA LQLSVHQDNN QRQYEAERNK GPGQRAPERL ESLLEKRKEL QEHQEEIEGM 
    MNALFRGVFV HRYRDVLPEI RAICIEEIGC WMQSYSTSFL TDSYLKYIGW TLHDKHREVR 
    LKCVKALKGL YGNRDLTTRL ELFTSRFKDR MVSMVMDREY DVAVEAVRLL ILILKNMEGV 
    LTDADCESVY PVVYASHRGL ASAAGEFLYW KLFYPECEIR MMGGREQRQS PGAQRTFFQL 
    LLSFFVESEL HDHAAYLVDS LWDCAGARLK DWEGLTSLLL EKDQNLGDVQ ESTLIEILVS 
    SARQASEGHP PVGRVTGRKG LTSKERKTQA DDRVKLTEHL IPLLPQLLAK FSADAEKVTP 
    LLQLLSCFDL HIYCTGRLEK HLELFLQQLQ EVVVKHAEPA VLEAGAHALY LLCNPEFTFF 
    SRADFARSQL VDLLTDRFQQ ELEELLQSSF LDEDEVYNLA ATLKRLSAFY NTHDLTRWEL 
    YEPCCQLLQK AVDTGEVPHQ VILPALTLVY FSILWTLTHI SKSDASQKQL SSLRDRMVAF 
    CELCQSCLSD VDTEIQEQAF VLLSDLLLIF SPQMIVGGRD FLRPLVFFPE ATLQSELASF 
    LMDHVFIQPG DLGSGDSQED HLQIERLHQR RRLLAGFCKL LLYGVLEMDA ASDVFKHYNK 
    FYNDYGDIIK ETLTRARQID RSHCSRILLL SLKQLYTELL QEHGPQGLNE LPAFIEMRDL 
    ARRFALSFGP QQLQNRDLVV MLHKEGIQFS LSELPPAGSS NQPPNLAFLE LLSEFSPRLF 
    HQDKQLLLSY LEKCLQHVSQ APGHPWGPVT TYCHSLSPVE NTAETSPQVL PSSKRRRVEG 
    PAKPNREDVS SSQEESLQLN SIPPTPTLTS TAVKSRQPLW GLKEMEEEDG SELDFAQGSQ 
    PVAGTERSRF LGPQYFQTPH NPSGPGLGNQ LMRLSLMEED EEEELEIQDE SNEERQDTDM 
    QASSYSSTSE RGLDLLDSTE LDIEDF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.