GIPC1 | ENSG00000123159 | NCBI 10755

Details for: GIPC1

Gene ID: 10755

Symbol: GIPC1

Ensembl ID: ENSG00000123159

Description: GIPC PDZ domain containing family member 1

Associated with

Fgfr1 ligand binding and activation
(R-HSA-190242)
Fgfr1b ligand binding and activation
(R-HSA-190370)
Fgfr1c ligand binding and activation
(R-HSA-190373)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr1
(R-HSA-5654736)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signal transduction
(R-HSA-162582)
Actin binding
(GO:0003779)
Cadherin binding
(GO:0045296)
Cell cortex
(GO:0005938)
Cellular response to interleukin-7
(GO:0098761)
Chemical synaptic transmission
(GO:0007268)
Cytoplasm
(GO:0005737)
Cytoplasmic vesicle
(GO:0031410)
Cytosol
(GO:0005829)
Dendritic shaft
(GO:0043198)
Dendritic spine
(GO:0043197)
Endothelial cell migration
(GO:0043542)
Extracellular exosome
(GO:0070062)
Glutamatergic synapse
(GO:0098978)
Glutamate secretion
(GO:0014047)
G protein-coupled receptor signaling pathway
(GO:0007186)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Myosin binding
(GO:0017022)
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process
(GO:0032435)
Positive regulation of cytokinesis
(GO:0032467)
Positive regulation of melanin biosynthetic process
(GO:0048023)
Positive regulation of transforming growth factor beta receptor signaling pathway
(GO:0030511)
Presynaptic modulation of chemical synaptic transmission
(GO:0099171)
Protein binding
(GO:0005515)
Protein targeting
(GO:0006605)
Regulation of protein stability
(GO:0031647)
Regulation of synaptic plasticity
(GO:0048167)
Schaffer collateral - ca1 synapse
(GO:0098685)
Signaling receptor binding
(GO:0005102)
Synaptic vesicle
(GO:0008021)
Vesicle membrane
(GO:0012506)

Other Information

Proteins

PDZ domain-containing protein GIPC1
A8K2I7_HUMAN

Genular Protein ID: 1786648287

Symbol: GIPC1_HUMAN

Name: PDZ domain-containing protein GIPC1

UniProtKB Accession Codes:

O14908 A8K4I3 A8MZG3 Q9BTC9

Database IDs:

Citations:

PubMed ID: 9770488

Title: GIPC, a PDZ domain containing protein, interacts specifically with the C-terminus of RGS-GAIP.

PubMed ID: 9770488

DOI: 10.1073/pnas.95.21.12340

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9482110

Title: The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.

PubMed ID: 9482110

DOI: 10.1038/sj.onc.1201567

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 32413282

Title: Expansion of GGC Repeat in GIPC1 Is Associated with Oculopharyngodistal Myopathy.

PubMed ID: 32413282

DOI: 10.1016/j.ajhg.2020.04.011

Sequence Information:

Length: 333
Mass: 36049
Checksum: AA980A4B907E3FD9
Sequence:

MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF 
HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE 
DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA 
INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR 
GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL 
AEALDERLGD FAFPDEFVFD VWGAIGDAKV GRY

Genular Protein ID: 3319057291

Symbol: A8K2I7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K2I7

Database IDs:

Sequence Information:

Length: 333
Mass: 36039
Checksum: AA980A49FDEE3FD9
Sequence:

MPLGLGRRKK APPLVENEEA EPGRGGLGVG EPGPLGGGGS GGPQMGLPPP PPALRPRLVF 
HTQLAHGSPT GRIEGFTNVK ELYGKIAEAF RLPTAEVMFC TLNTHKVDMD KLLGGQIGLE 
DFIFAHVKGQ RKEVEVFKSE DALGLTITDN GAGYAFIKRI KEGSVIDHIH LISVGDMIEA 
INGQSLLGCR HYEVARLLKE LPRGRTFTLK LTEPRKAFDM ISQRSAGGRP GSGPQLGTGR 
GTLRLRSRGP ATVEDLPSAF EEKAIEKVDD LLESYMGIRD TELAATMVEL GKDKRNPDEL 
AEALDERLGD FAFSDEFVFD VWGAIGDAKV GRY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: GIPC1

Associated with

Other Information

GIPC, a PDZ domain containing protein, interacts specifically with the C-terminus of RGS-GAIP. PubMed ID: 9770488

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and biology of human chromosome 19. PubMed ID: 15057824

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins. PubMed ID: 9482110

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

Expansion of GGC Repeat in GIPC1 Is Associated with Oculopharyngodistal Myopathy. PubMed ID: 32413282