Details for: SRSF10

Gene ID: 10772

Symbol: SRSF10

Ensembl ID: ENSG00000188529

Description: serine and arginine rich splicing factor 10

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 6.66
    Marker Score: 88,536
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 3.5
    Marker Score: 1,701
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 3.23
    Marker Score: 2,161
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: 3.2
    Marker Score: 1,941
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 3.12
    Marker Score: 2,782
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 2.83
    Marker Score: 1,997
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.73
    Marker Score: 92,938
  • Cell Name: IgG-negative class switched memory B cell (CL0002117)
    Fold Change: 2.66
    Marker Score: 2,622
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.64
    Marker Score: 2,805
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.63
    Marker Score: 139,188
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.61
    Marker Score: 2,784
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.52
    Marker Score: 56,208
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 2.52
    Marker Score: 33,176
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.43
    Marker Score: 7,669
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.42
    Marker Score: 24,538
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.31
    Marker Score: 15,022
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 2.31
    Marker Score: 2,405
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 2.3
    Marker Score: 675
  • Cell Name: CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell (CL0000915)
    Fold Change: 2.3
    Marker Score: 3,250
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 2.29
    Marker Score: 3,886
  • Cell Name: class switched memory B cell (CL0000972)
    Fold Change: 2.27
    Marker Score: 2,130
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.26
    Marker Score: 4,728
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 2.25
    Marker Score: 1,495
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 2.24
    Marker Score: 2,055
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.23
    Marker Score: 2,100
  • Cell Name: enteric neuron (CL0007011)
    Fold Change: 2.23
    Marker Score: 1,186
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 2.21
    Marker Score: 6,571
  • Cell Name: central memory CD8-positive, alpha-beta T cell (CL0000907)
    Fold Change: 2.21
    Marker Score: 5,386
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.2
    Marker Score: 22,126
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.19
    Marker Score: 1,597
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.18
    Marker Score: 1,366
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 2.17
    Marker Score: 1,703
  • Cell Name: IgG memory B cell (CL0000979)
    Fold Change: 2.17
    Marker Score: 1,306
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 2.17
    Marker Score: 9,002
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.16
    Marker Score: 25,124
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2.15
    Marker Score: 12,780
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 2.15
    Marker Score: 5,850
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.14
    Marker Score: 2,271
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: 2.13
    Marker Score: 787
  • Cell Name: smooth muscle cell of large intestine (CL1000279)
    Fold Change: 2.13
    Marker Score: 805
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: 2.11
    Marker Score: 1,179
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.11
    Marker Score: 5,751
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 2.1
    Marker Score: 7,461
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.1
    Marker Score: 2,240
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 2.09
    Marker Score: 2,108
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 2.07
    Marker Score: 3,436
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 2.06
    Marker Score: 2,223
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.06
    Marker Score: 662
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 2.06
    Marker Score: 1,562
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 2.06
    Marker Score: 1,492
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 2.05
    Marker Score: 725
  • Cell Name: T-helper 22 cell (CL0001042)
    Fold Change: 2.05
    Marker Score: 8,775
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.05
    Marker Score: 1,797
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.04
    Marker Score: 487
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 2.03
    Marker Score: 7,499
  • Cell Name: CD38-negative naive B cell (CL0002102)
    Fold Change: 2.02
    Marker Score: 4,237
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.02
    Marker Score: 871
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 2.02
    Marker Score: 1,711
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2
    Marker Score: 2,775
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 2
    Marker Score: 1,136
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 2
    Marker Score: 1,638
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.99
    Marker Score: 752
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.99
    Marker Score: 1,864
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.99
    Marker Score: 5,334
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.98
    Marker Score: 8,298
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.98
    Marker Score: 22,321
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.98
    Marker Score: 4,997
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.98
    Marker Score: 989
  • Cell Name: CD4-positive helper T cell (CL0000492)
    Fold Change: 1.97
    Marker Score: 2,148
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.97
    Marker Score: 68,200
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.97
    Marker Score: 2,784
  • Cell Name: memory B cell (CL0000787)
    Fold Change: 1.96
    Marker Score: 1,484
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.96
    Marker Score: 8,021
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.96
    Marker Score: 3,765
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.95
    Marker Score: 582
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 1.95
    Marker Score: 2,872
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 1.95
    Marker Score: 1,881
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.95
    Marker Score: 2,622
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 1.94
    Marker Score: 1,070
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: 1.94
    Marker Score: 1,138
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.94
    Marker Score: 5,539
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.94
    Marker Score: 2,091
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.93
    Marker Score: 2,035
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.93
    Marker Score: 2,337
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.93
    Marker Score: 2,842
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.92
    Marker Score: 9,425
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 1.92
    Marker Score: 2,028
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 1.91
    Marker Score: 2,000
  • Cell Name: effector memory CD4-positive, alpha-beta T cell (CL0000905)
    Fold Change: 1.91
    Marker Score: 1,396
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 1.9
    Marker Score: 3,572
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.89
    Marker Score: 1,964
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 1.88
    Marker Score: 2,900
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.88
    Marker Score: 2,504
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.88
    Marker Score: 659
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.88
    Marker Score: 1,252
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.87
    Marker Score: 601
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.87
    Marker Score: 13,893
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.86
    Marker Score: 757
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.84
    Marker Score: 642
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.84
    Marker Score: 4,328

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Serine and Arginine Rich Domain**: SRSF10 contains a serine and arginine rich domain, which is a hallmark of splicing factors. This domain is essential for its interaction with other splicing factors and the RNA substrate. 2. **Spliceosome Assembly**: SRSF10 is involved in the assembly of the spliceosome, a complex that catalyzes the removal of introns and the joining of exons during RNA splicing. 3. **Alternative Splicing Regulation**: SRSF10 regulates alternative splicing, a mechanism that allows a single gene to produce multiple protein isoforms. This is achieved through the recruitment of other splicing factors and the modulation of splice site selection. 4. **Cell-Type Specific Expression**: SRSF10 is expressed in various cell types, including cardiac muscle cells, myeloid dendritic cells, and kidney epithelial cells, highlighting its importance in tissue-specific gene expression. **Pathways and Functions** 1. **RNA Splicing**: SRSF10 is involved in the RNA splicing process, which involves the removal of introns and the joining of exons. 2. **Spliceosome Assembly**: SRSF10 plays a crucial role in the assembly of the spliceosome, a complex that catalyzes the RNA splicing process. 3. **Alternative Splicing Regulation**: SRSF10 regulates alternative splicing, a mechanism that allows a single gene to produce multiple protein isoforms. 4. **Regulation of Gene Expression**: SRSF10 influences gene expression by modulating the alternative splicing of target genes, thereby affecting the production of functional protein isoforms. **Clinical Significance** 1. **Disease Association**: Alterations in SRSF10 expression have been associated with various diseases, including cancer, where changes in splicing patterns can impact tumor progression and metastasis. 2. **Immune System**: SRSF10 plays a critical role in the regulation of immune cell subsets, such as CD14-low, CD16-positive monocytes, which are involved in the immune response against pathogens. 3. **Tissue Repair**: SRSF10 is expressed in cardiac muscle cells and other cell types involved in tissue repair, highlighting its potential role in maintaining tissue homeostasis. 4. **Cancer Therapy**: Targeting SRSF10 and its associated splicing factors may provide a novel therapeutic strategy for cancer treatment, particularly in cases where alternative splicing patterns contribute to tumor progression. In conclusion, SRSF10 is a critical component of the spliceosome, regulating alternative splicing and influencing gene expression in various cell types. Its clinical significance is underscored by its association with disease, the immune system, and tissue repair, highlighting the potential for therapeutic targeting of this gene in cancer and other diseases.

Genular Protein ID: 857370986

Symbol: SRS10_HUMAN

Name: Serine/arginine-rich splicing factor 10

UniProtKB Accession Codes:

O75494 A6NFM6 A6NI42 A6NIU7 B4DJP9 O60572 Q5JRH9 Q5JRI0 Q5JRI2 Q5JRI3 Q5JRI4 Q96G09 Q96P17

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 6 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 16 EPD 1 Ensembl 6 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 2 RefSeq 6 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 5 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9774382

Title: Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.

PubMed ID: 9774382

DOI: 10.1074/jbc.273.43.27761

PubMed ID: 10779324

Title: TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins.

PubMed ID: 10779324

DOI: 10.1128/mcb.20.10.3345-3354.2000

PubMed ID: 11684676

Title: Serine-arginine (SR) protein-like factors that antagonize authentic SR proteins and regulate alternative splicing.

PubMed ID: 11684676

DOI: 10.1074/jbc.m103967200

PubMed ID: 12419250

Title: The SR protein SRp38 represses splicing in M Phase cells.

PubMed ID: 12419250

DOI: 10.1016/s0092-8674(02)01038-3

PubMed ID: 11891055

Title: Characterization and expression of the human gene encoding two translocation liposarcoma protein-associated serine-arginine (TASR) proteins.

PubMed ID: 11891055

DOI: 10.1016/s0378-1119(02)00382-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14765198

Title: Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock.

PubMed ID: 14765198

DOI: 10.1038/nature02288

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26876937

Title: Nuclear m(6)A reader YTHDC1 regulates mRNA splicing.

PubMed ID: 26876937

DOI: 10.1016/j.molcel.2016.01.012

Sequence Information:

  • Length: 262
  • Mass: 31301
  • Checksum: 205F95D36CBBFAB4
  • Sequence:
    • MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED 
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR 
SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR 
SRSKSQPKKE MKAKSRSRSA SHTKTRGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR 
SQSRSRSKSR SRSWTSPKSS GH

Genular Protein ID: 1193977876

Symbol: B3KNY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KNY6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 4 GenomeRNAi 1 NCBI Taxonomy 1 OrthoDB 1 PeptideAtlas 1 RefSeq 3 SAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 167
  • Mass: 19993
  • Checksum: 957B1E5C75C592EB
  • Sequence:
    • MKAKEGRNVY SSSRYDDYDR YRRSRSRSYE RRRSRSRSFD YNYRRSYSPR NSRPTGRPRR 
SRSHSDNDRF KHRNRSFSRS KSNSRSRSKS QPKKEMKAKS RSRSASHTKT RGTSKTDSKT 
HYKSGSRYEK ESRKKEPPRS KSQSRSQSRS RSKSRSRSWT SPKSSGH

Genular Protein ID: 3702133397

Symbol: Q5JRI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5JRI1

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 2 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 IntAct 1 InterPro 3 MINT 1 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.M800588-MCP200

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 172
  • Mass: 20913
  • Checksum: 0947F29C81A94681
  • Sequence:
    • MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED 
VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR 
SRSYERRRSR SRSFDYNYRR SYSPRNRPTG RPRRSRSHSD NDSQVSKKKN ER

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.