Details for: IQGAP2

Gene ID: 10788

Symbol: IQGAP2

Ensembl ID: ENSG00000145703

Description: IQ motif containing GTPase activating protein 2

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 4.41
    Marker Score: 5,496
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.48
    Marker Score: 11,389
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.93
    Marker Score: 856
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 2.45
    Marker Score: 1,056
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.3
    Marker Score: 9,627
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 2.15
    Marker Score: 8,810
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 2.08
    Marker Score: 1,705
  • Cell Name: podocyte (CL0000653)
    Fold Change: 2.03
    Marker Score: 752
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.99
    Marker Score: 1,994
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.93
    Marker Score: 4,395
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 1.92
    Marker Score: 595
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: 1.82
    Marker Score: 5,105
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.79
    Marker Score: 3,934
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.78
    Marker Score: 4,436
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.76
    Marker Score: 17,886
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.76
    Marker Score: 9,476
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.76
    Marker Score: 1,357
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.73
    Marker Score: 11,115
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 1.73
    Marker Score: 621
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.73
    Marker Score: 1,251
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.71
    Marker Score: 95,824
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 1.7
    Marker Score: 1,762
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 1.69
    Marker Score: 888
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: 1.69
    Marker Score: 1,928
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 1.69
    Marker Score: 8,087
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.67
    Marker Score: 1,140
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 1.65
    Marker Score: 617
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.65
    Marker Score: 7,114
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.65
    Marker Score: 560
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 1.64
    Marker Score: 3,722
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.62
    Marker Score: 513
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.62
    Marker Score: 5,990
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.61
    Marker Score: 3,783
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 1.59
    Marker Score: 744
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.56
    Marker Score: 9,947
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.49
    Marker Score: 481
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 1.48
    Marker Score: 726
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 1.47
    Marker Score: 1,378
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.47
    Marker Score: 424
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.46
    Marker Score: 729
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.45
    Marker Score: 166,739
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.44
    Marker Score: 961
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.43
    Marker Score: 860
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: 1.43
    Marker Score: 1,202
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 1.43
    Marker Score: 9,121
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.41
    Marker Score: 495
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 1.41
    Marker Score: 13,983
  • Cell Name: memory regulatory T cell (CL0002678)
    Fold Change: 1.4
    Marker Score: 490
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.39
    Marker Score: 2,633
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.38
    Marker Score: 343
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.37
    Marker Score: 409
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 1.36
    Marker Score: 837
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 1.35
    Marker Score: 1,364
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: 1.35
    Marker Score: 1,988
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.34
    Marker Score: 4,232
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.34
    Marker Score: 23,776
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.34
    Marker Score: 1,434
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 1.32
    Marker Score: 3,864
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 1.31
    Marker Score: 3,311
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 1.31
    Marker Score: 398
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.29
    Marker Score: 749
  • Cell Name: Unknown (CL0000548)
    Fold Change: 1.27
    Marker Score: 929
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 1.27
    Marker Score: 3,521
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 1.27
    Marker Score: 324
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.26
    Marker Score: 4,469
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 1.25
    Marker Score: 1,102
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.25
    Marker Score: 31,988
  • Cell Name: blood cell (CL0000081)
    Fold Change: 1.21
    Marker Score: 14,072
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.2
    Marker Score: 4,135
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 1.2
    Marker Score: 2,534
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 1.2
    Marker Score: 385
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.2
    Marker Score: 375
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 1.19
    Marker Score: 789
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.17
    Marker Score: 3,668
  • Cell Name: dendritic cell, human (CL0001056)
    Fold Change: 1.17
    Marker Score: 1,189
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.17
    Marker Score: 1,608
  • Cell Name: CD56-positive, CD161-positive immature natural killer cell, human (CL0002338)
    Fold Change: 1.16
    Marker Score: 382
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 1.15
    Marker Score: 262
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 1.15
    Marker Score: 1,389
  • Cell Name: peptic cell (CL0000155)
    Fold Change: 1.15
    Marker Score: 481
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 1.15
    Marker Score: 1,523
  • Cell Name: CD14-positive, CD16-positive monocyte (CL0002397)
    Fold Change: 1.14
    Marker Score: 2,224
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 1.14
    Marker Score: 223
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.13
    Marker Score: 773
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: 1.13
    Marker Score: 661
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.12
    Marker Score: 226
  • Cell Name: CD16-negative, CD56-bright natural killer cell, human (CL0000938)
    Fold Change: 1.12
    Marker Score: 916
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 1.11
    Marker Score: 1,434
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.11
    Marker Score: 1,564
  • Cell Name: central memory CD4-positive, alpha-beta T cell (CL0000904)
    Fold Change: 1.1
    Marker Score: 1,191
  • Cell Name: lung microvascular endothelial cell (CL2000016)
    Fold Change: 1.1
    Marker Score: 234
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 1.1
    Marker Score: 687
  • Cell Name: macrophage (CL0000235)
    Fold Change: 1.09
    Marker Score: 1,213
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.09
    Marker Score: 634
  • Cell Name: IgG plasmablast (CL0000982)
    Fold Change: 1.07
    Marker Score: 294
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: 1.06
    Marker Score: 366
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.06
    Marker Score: 1,056
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 1.05
    Marker Score: 1,005
  • Cell Name: mesenchymal lymphangioblast (CL0005021)
    Fold Change: 1.05
    Marker Score: 234
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 1.04
    Marker Score: 360

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **IQ motif**: IQGAP2 contains an IQ motif, a conserved protein-protein interaction domain that binds to the actin cytoskeleton. 2. **GTPase activating activity**: IQGAP2 has GTPase activating activity, which means it can accelerate the hydrolysis of GTP to GDP, thereby regulating the activity of small GTPases. 3. **Actin cytoskeleton binding**: IQGAP2 interacts with the actin cytoskeleton, influencing its organization and dynamics. 4. **Cell surface localization**: IQGAP2 is localized to the cell surface, where it can interact with various receptors and signaling molecules. 5. **Immune system involvement**: IQGAP2 is highly expressed in immune cells, where it plays a role in regulating immune responses, including neutrophil degranulation and T cell activation. **Pathways and Functions** 1. **Rho GTPase signaling**: IQGAP2 interacts with Rho GTPases, such as RhoA, Rac1, and Cdc42, and regulates their activity. 2. **Actin cytoskeleton organization**: IQGAP2 influences the organization and dynamics of the actin cytoskeleton, which is essential for cell migration, shape changes, and cell signaling. 3. **Immune response regulation**: IQGAP2 plays a role in regulating immune responses, including neutrophil degranulation, T cell activation, and cytokine secretion. 4. **Neuronal function**: IQGAP2 is expressed in cardiac neurons and plays a role in regulating neuronal function and signaling. 5. **Epithelial cell function**: IQGAP2 is expressed in epithelial cells and influences their function, including cell migration and signaling. **Clinical Significance** 1. **Cancer**: IQGAP2 has been implicated in cancer progression, including metastasis and tumor growth. 2. **Neurological disorders**: IQGAP2 has been linked to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. 3. **Immune system disorders**: IQGAP2 has been implicated in immune system disorders, including autoimmune diseases and immunodeficiency diseases. 4. **Cardiovascular disease**: IQGAP2 has been linked to cardiovascular disease, including hypertension and atherosclerosis. 5. **Regulatory T cells**: IQGAP2 has been shown to play a role in the regulation of regulatory T cells, which are essential for maintaining immune tolerance. In conclusion, IQGAP2 is a multifunctional protein that plays a crucial role in various cellular processes, including cell signaling, cytoskeletal organization, and immune response. Its unique ability to interact with both the actin cytoskeleton and small GTPases makes it an important regulator of cytoskeletal dynamics and cell migration. IQGAP2's involvement in various diseases, including cancer, neurological disorders, and immune system disorders, highlights its potential as a therapeutic target.

Genular Protein ID: 41845908

Symbol: IQGA2_HUMAN

Name: Ras GTPase-activating-like protein IQGAP2

UniProtKB Accession Codes:

Q13576 A8K4V1 B7Z8A4 J3KR91

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 CarbonylDB 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OGP 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 3 PRO 1 PROSITE 6 PROSITE-ProRule 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8756646

Title: The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases.

PubMed ID: 8756646

DOI: 10.1128/mcb.16.9.4869

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23033978

Title: Diagnostic exome sequencing in persons with severe intellectual disability.

PubMed ID: 23033978

DOI: 10.1056/nejmoa1206524

Sequence Information:

  • Length: 1575
  • Mass: 180578
  • Checksum: BCC8CED6645CB09B
  • Sequence:
    • MPHEELPSLQ RPRYGSIVDD ERLSAEEMDE RRRQNIAYEY LCHLEEAKRW MEVCLVEELP 
PTTELEEGLR NGVYLAKLAK FFAPKMVSEK KIYDVEQTRY KKSGLHFRHT DNTVQWLRAM 
ESIGLPKIFY PETTDVYDRK NIPRMIYCIH ALSLYLFKLG IAPQIQDLLG KVDFTEEEIS 
NMRKELEKYG IQMPSFSKIG GILANELSVD EAALHAAVIA INEAVEKGIA EQTVVTLRNP 
NAVLTLVDDN LAPEYQKELW DAKKKKEENA RLKNSCISEE ERDAYEELLT QAEIQGNINK 
VNRQAAVDHI NAVIPEGDPE NTLLALKKPE AQLPAVYPFA AAMYQNELFN LQKQNTMNYL 
AHEELLIAVE MLSAVALLNQ ALESNDLVSV QNQLRSPAIG LNNLDKAYVE RYANTLLSVK 
LEVLSQGQDN LSWNEIQNCI DMVNAQIQEE NDRVVAVGYI NEAIDEGNPL RTLETLLLPT 
ANISDVDPAH AQHYQDVLYH AKSQKLGDSE SVSKVLWLDE IQQAVDDANV DKDRAKQWVT 
LVVDVNQCLE GKKSSDILSV LKSSTSNAND IIPECADKYY DALVKAKELK SERVSSDGSW 
LKLNLHKKYD YYYNTDSKES SWVTPESCLY KESWLTGKEI EDIIEEVTVG YIRENIWSAS 
EELLLRFQAT SSGPILREEF EARKSFLHEQ EENVVKIQAF WKGYKQRKEY MHRRQTFIDN 
TDSIVKIQSW FRMATARKSY LSRLQYFRDH NNEIVKIQSL LRANKARDDY KTLVGSENPP 
LTVIRKFVYL LDQSDLDFQE ELEVARLREE VVTKIRANQQ LEKDLNLMDI KIGLLVKNRI 
TLEDVISHSK KLNKKKGGEM EILNNTDNQG IKSLSKERRK TLETYQQLFY LLQTNPLYLA 
KLIFQMPQNK STKFMDTVIF TLYNYASNQR EEYLLLKLFK TALEEEIKSK VDQVQDIVTG 
NPTVIKMVVS FNRGARGQNT LRQLLAPVVK EIIDDKSLII NTNPVEVYKA WVNQLETQTG 
EASKLPYDVT TEQALTYPEV KNKLEASIEN LRRVTDKVLN SIISSLDLLP YGLRYIAKVL 
KNSIHEKFPD ATEDELLKIV GNLLYYRYMN PAIVAPDGFD IIDMTAGGQI NSDQRRNLGS 
VAKVLQHAAS NKLFEGENEH LSSMNNYLSE TYQEFRKYFK EACNVPEPEE KFNMDKYTDL 
VTVSKPVIYI SIEEIISTHS LLLEHQDAIA PEKNDLLSEL LGSLGEVPTV ESFLGEGAVD 
PNDPNKANTL SQLSKTEISL VLTSKYDIED GEAIDSRSLM IKTKKLIIDV IRNQPGNTLT 
EILETPATAQ QEVDHATDMV SRAMIDSRTP EEMKHSQSMI EDAQLPLEQK KRKIQRNLRT 
LEQTGHVSSE NKYQDILNEI AKDIRNQRIY RKLRKAELAK LQQTLNALNK KAAFYEEQIN 
YYDTYIKTCL DNLKRKNTRR SIKLDGKGEP KGAKRAKPVK YTAAKLHEKG VLLDIDDLQT 
NQFKNVTFDI IATEDVGIFD VRSKFLGVEM EKVQLNIQDL LQMQYEGVAV MKMFDKVKVN 
VNLLIYLLNK KFYGK

Genular Protein ID: 527644307

Symbol: Q59HA3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59HA3

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 4 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 1155
  • Mass: 132687
  • Checksum: 3FBD3142ACD684E7
  • Sequence:
    • LEVLSQGQDN LSWNEIQNCI DMVNAQIQEE NDRVVAVGYI NEAIDEGNPL RTLETLLLPT 
ANISDVDPAH AQHYQDVLYH AKSQKLGDSE SVSKVLWLDE IQQAVDEANV DEDRAKQWVT 
LVVDVNQCLE GKKSSDILSV LKSSTSNAND IIPECADKYY DALVKAKELK SERVSSDGSW 
LKLNLHKKYD YYYNTDSKES SWVTPESCLY KESWLTGKEI EDIIEEVTVG YIRENIWSAS 
EELLLRFQAT SSGPILREEF EARKSFLHEQ EENVVKIQAF WKGYKQRKEY MHRRQTFIDN 
TDSIVKIQSW FRMATARKSY LSRLQYFRDH NNEIVKIQSL LRANKARDDY KTLVGSENPP 
LTVIRKFVYL LDQSDLDFQE ELEVARLREE VVTKIRANQQ LEKDLNLMDI KIGLLVKNRI 
TLEDVISHSK KLNKKKGGEM EILNNTDNQG IKSLSKERRK TLETYQQLFY LLQTNPLYLA 
KLIFQMPQNK STKFMDTVIF TLYNYASNQR EEYLLLKLFK TALEEEIKSK VDQVQDIVTG 
NPTVIKMVVS FNRGARGQNT LRQLLAPVVK EIIDDKSLII NTNPVEVYKA WVNQLETQTG 
EASKLPYDVT TEQALTYPEV KNKLEASIEN LRRVTDKVLN SIISSLDLLP YGLRYIAKVL 
KNSIHEKFPD ATEDELLKIV GNLLYYRYMN PAIVAPDGFD IIDMTAGGQI NSDQRRNLGS 
VAKVLQHAAS NKLFEGENEH LSSMNNYLSE TYQEFRKYFK EACNVPEPEE KFNMDKYTDL 
VTVSKPVIYI SIEEIISTHS LLLEHQDAIA PEKNDLLSEL LGSLGEVPTV ESFLGEGAVD 
PNDPNKANTL SQLSKTEISL VLTSKYDIED GEAIDSRSLM IKTKKLIIDV IRNQPGNTLT 
EILETPATAQ QEVDHATDMV SRAMIDSRTP EEMKHSQSMI EDAQLPLEQK KRKIQRNLRT 
LEQTGHVSSE NKYQDILNEI AKDIRNQRIY RKLRKAELAK LQQTLNALNK KAAFYEEQIN 
YYDTYIKTCL DNLKRKNTRR SIKLDGKGEP KGAKRAKPVK YTAAKLHEKG VLLDIDDLQT 
NQFKNVTFDI IATEDVGIFD VRSKFLGVEM EKVQLNIQDL LQMQYEGVAV MKMFDKVKVN 
VNLLIYLLNK KFYGK

Genular Protein ID: 284617670

Symbol: B7Z7X2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7X2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 Gene3D 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 1 RefSeq 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 377
  • Mass: 43671
  • Checksum: FD3E668D32ED6FF9
  • Sequence:
    • MGCFKGVVAV GYINEAIDEG NPLRTLETLL LPTANISDVD PAHAQHYQDV LYHAKSQKLG 
DSESVSKVLW LDEIQQAVDE ANVDEDRAKQ WVTLVVDVNQ CLEGKKSSDI LSVLKSSTSN 
ANDIIPECAD KYYDALVKAK ELKSERVSSD GSWLKLNLHK KYDYYYNTDS KESSWVTPES 
CLYKESWLTG KEIEDIIEEV TVGYIRENIW SASEELLLRF QATSSGPILR EEFEARKSFL 
HEQEENVVKI QAFWKGYKQR KEYMHRRQTF IDNTDSIVKI QSWFRMATAR KSYLSRLQYF 
RDHNNEIVKI QSLLRANKAR DDYKTLVGSE NPPLTVIRKF VYLLDQSDLD FQEELEVARL 
REEVVTKIRA NQQLEKT

Genular Protein ID: 3129271757

Symbol: B7Z7U6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7U6

Database IDs:

BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 GenomeRNAi 1 IntAct 1 InterPro 8 KEGG 1 MINT 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 9 PeptideAtlas 1 Pfam 4 RefSeq 3 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 1402
  • Mass: 160251
  • Checksum: 0DF41EA5BE56239A
  • Sequence:
    • MEVCLVEELP PTTVLEEGLR NGVYLAKLAK FFAPKMVSEK KIYDVEQTRY KKSGLHFRHT 
DNTVQWLRAM ESIGLPKIFY PETTDVYDRK NIPRMIYCIH ALSLYLFKLG IAPQIQDLLG 
KVDFTEEEIS NMRKELEKYG IQMPSFSKIG GILANELSVD EAALHAAVIA INEAVEKGIA 
EQTVVTLRNP NAVLTLVDDN LAPEHQKELW DAKKKKEENA RLKNSCISEE ERDAYEELLT 
QAEIQGNINK VNRQAAVDHI NAVIPEGDPE NTLLALKKPE AQLPAVYPFA AAMYQNELFN 
LQKQNTMNYL AHEELLIAVE MLSAVALLNQ ALESNDLVSV QNQLRSPAIG LNNLDKAYVE 
RYANTLLSVK LEVLSQGQDN LSWNEIQNCI DMVNAQIQEE NDRVVAVGYI NEAIDEGNPL 
RTLETLLLPT ANISDVDPAH AQHYQDVLYH AKSQKLGDSE SVSKVLWLDE IQQAVDDANV 
DEDRAKQWVT LVVDVNQCLE GKKSSDILSV LKSSTSNAND IIPECADKYY DALVKAKELK 
SERVSSDGSW LKLNLHKKYD YYYNTDSKES SWVTPESCLY KESWLTGKEI EDIIEEVTVG 
YIRENIWSAS EELLLRFQAT SSGPILREEF EARKSFLHEQ EENVVKIQAF WKGYKQRKEY 
MHRRQTFIDN TDSIVKIQSW FRMATARKSY LSRLQYFRDH NNEIVKIQSL LRANKARDDY 
KTLVGSENPP LTVIRKFVYL LDQSDLDFQE ELEVARLREE VVTKIRANQQ LEKDLNLMDI 
KIGLLVKNRI TLEDVISHSK KLNKKKGGEM EILNNTDNQG IKSLSKERRK TLETYQQLFY 
LLQTNPLYLA KLIFQMPQNK STKFMDTVIF TLYNYASNQR EEYLLLKLFK TALEEEIKSK 
VDQVQDIVTG NPTVIKMVAS FNRGARGQNT LRQLLAPVVK EIIDDKSLII NTNPVEVYKA 
WVNQLETQTG EASKLPYDVT TEQALTYPEV KNKLEASIEN LRRVTDKVLN SIISSLDLLP 
YGLRYIAKVL KNSIHEKFPD ATEDELLKIV GNLLYYRYMN PAIVAPDGFD IIDMTAGGQI 
NSDQRRNLGS VAKVLQHAAS NKLFEGENEH LSSMNNYLSE TYQEFRKYFK EACNVPEPEE 
KFNMDKYTDL VTVSKPVIYI SIEEIISTHS LLLEHQDAIA PEKNDLLSEL LGSLGEVPTV 
ESFLGEGAVD PNDPNKANTL SQLSKTEISL VLTSKYDIED GEAIDSRSLM IKTKKLIIDV 
IRNQPGNTLT EILETPATAQ QEVDHATDMV SRAMIDSRTP EEMKHSQSMI EDAQLPLEQK 
KRKIQRNLRT LEQTGHVSSE NKYQDILNEI AKDIRNQRIY RKLRKAELAK LQQTLNALNK 
KAAFYEEQIN YYDTYIKTCL DN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.