Details for: ADCY2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 301.9701
Cell Significance Index: -46.9700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 188.6507
Cell Significance Index: -47.8500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 43.2472
Cell Significance Index: -41.2900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 38.1684
Cell Significance Index: -47.0600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 12.1286
Cell Significance Index: -47.8600 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 9.3553
Cell Significance Index: 130.8200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.3472
Cell Significance Index: -16.0800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 6.1600
Cell Significance Index: 158.3400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 6.0145
Cell Significance Index: 146.7500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 4.2712
Cell Significance Index: 1532.0000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.0455
Cell Significance Index: 610.9200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.8318
Cell Significance Index: 80.8100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 2.7084
Cell Significance Index: 43.7000 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 2.6403
Cell Significance Index: 34.2400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.5492
Cell Significance Index: 1071.4600 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.2455
Cell Significance Index: 13.8400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 1.1931
Cell Significance Index: 15.9200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.1095
Cell Significance Index: 74.6000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.1038
Cell Significance Index: 23.6000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.9855
Cell Significance Index: 24.6400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.8917
Cell Significance Index: 54.8100 - Cell Name: chandelier cell (CL4023083)
Fold Change: 0.7480
Cell Significance Index: 6.0400 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.4691
Cell Significance Index: 8.1100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.4131
Cell Significance Index: 777.7800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2935
Cell Significance Index: 7.0400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2379
Cell Significance Index: 214.7700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.1936
Cell Significance Index: 5.4100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1841
Cell Significance Index: 35.0400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1292
Cell Significance Index: 82.0500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.1068
Cell Significance Index: 1.6100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1013
Cell Significance Index: 2.9200 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.0915
Cell Significance Index: 0.6200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0588
Cell Significance Index: 26.7100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0054
Cell Significance Index: 3.3500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0002
Cell Significance Index: -0.0300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0097
Cell Significance Index: -17.8100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0196
Cell Significance Index: -30.1100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0212
Cell Significance Index: -0.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0217
Cell Significance Index: -29.4600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0241
Cell Significance Index: -17.8500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0443
Cell Significance Index: -0.9400 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0451
Cell Significance Index: -4.4700 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0508
Cell Significance Index: -1.0200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0522
Cell Significance Index: -1.8400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0573
Cell Significance Index: -32.3300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0580
Cell Significance Index: -9.4300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0681
Cell Significance Index: -51.5600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0724
Cell Significance Index: -32.0200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0730
Cell Significance Index: -13.1600 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0830
Cell Significance Index: -45.3500 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0838
Cell Significance Index: -1.0400 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.0897
Cell Significance Index: -0.9900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1068
Cell Significance Index: -1.5300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.1218
Cell Significance Index: -13.2500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1249
Cell Significance Index: -7.0100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1368
Cell Significance Index: -8.3900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1401
Cell Significance Index: -3.0400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1405
Cell Significance Index: -14.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1412
Cell Significance Index: -40.6300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1472
Cell Significance Index: -29.2100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1539
Cell Significance Index: -32.4200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1887
Cell Significance Index: -32.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2117
Cell Significance Index: -6.9300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.2301
Cell Significance Index: -10.4300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2579
Cell Significance Index: -15.4800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2647
Cell Significance Index: -36.3500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2912
Cell Significance Index: -35.8100 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.3038
Cell Significance Index: -2.3300 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.3295
Cell Significance Index: -3.5900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.3439
Cell Significance Index: -44.0800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3512
Cell Significance Index: -45.3700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3515
Cell Significance Index: -40.2700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3682
Cell Significance Index: -25.4700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3865
Cell Significance Index: -9.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3908
Cell Significance Index: -12.4500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.3990
Cell Significance Index: -46.5000 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.4131
Cell Significance Index: -5.7900 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.4194
Cell Significance Index: -4.8000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4245
Cell Significance Index: -48.4600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.4392
Cell Significance Index: -9.4900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.4407
Cell Significance Index: -45.0200 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.4437
Cell Significance Index: -6.7500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.5455
Cell Significance Index: -41.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.5943
Cell Significance Index: -44.2900 - Cell Name: neural cell (CL0002319)
Fold Change: -0.6832
Cell Significance Index: -7.9700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.6838
Cell Significance Index: -35.5200 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.6911
Cell Significance Index: -30.0500 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.7235
Cell Significance Index: -8.7700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7249
Cell Significance Index: -38.0600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.7277
Cell Significance Index: -46.9500 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.7483
Cell Significance Index: -47.1600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7610
Cell Significance Index: -26.6600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.7963
Cell Significance Index: -41.4800 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.8503
Cell Significance Index: -10.7300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.8521
Cell Significance Index: -16.6300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.8850
Cell Significance Index: -18.4700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.9006
Cell Significance Index: -28.8500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.9147
Cell Significance Index: -42.9900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.9272
Cell Significance Index: -43.2300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.9842
Cell Significance Index: -37.2700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2995545697
Symbol: ADCY2_HUMAN
Name: Adenylate cyclase type 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10470851
Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10470851
PubMed ID: 1427768
Title: Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.
PubMed ID: 1427768
DOI: 10.1007/bf00210755
PubMed ID: 8476432
Title: A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.
PubMed ID: 8476432
PubMed ID: 11549699
Title: Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.
PubMed ID: 11549699
PubMed ID: 15385642
Title: Raf kinase activation of adenylyl cyclases: isoform-selective regulation.
PubMed ID: 15385642
DOI: 10.1124/mol.66.4.921
PubMed ID: 21228062
Title: Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains.
PubMed ID: 21228062
Sequence Information:
- Length: 1091
- Mass: 123603
- Checksum: 41FD8BC607C075D1
- Sequence:
MWQEAMRRRR YLRDRSEEAA GGGDGLPRSR DWLYESYYCM SQQHPLIVFL LLIVMGSCLA LLAVFFALGL EVEDHVAFLI TVPTALAIFF AIFILVCIES VFKKLLRLFS LVIWICLVAM GYLFMCFGGT VSPWDQVSFF LFIIFVVYTM LPFNMRDAII ASVLTSSSHT IVLSVCLSAT PGGKEHLVWQ ILANVIIFIC GNLAGAYHKH LMELALQQTY QDTCNCIKSR IKLEFEKRQQ ERLLLSLLPA HIAMEMKAEI IQRLQGPKAG QMENTNNFHN LYVKRHTNVS ILYADIVGFT RLASDCSPGE LVHMLNELFG KFDQIAKENE CMRIKILGDC YYCVSGLPIS LPNHAKNCVK MGLDMCEAIK KVRDATGVDI NMRVGVHSGN VLCGVIGLQK WQYDVWSHDV TLANHMEAGG VPGRVHISSV TLEHLNGAYK VEEGDGDIRD PYLKQHLVKT YFVINPKGER RSPQHLFRPR HTLDGAKMRA SVRMTRYLES WGAAKPFAHL HHRDSMTTEN GKISTTDVPM GQHNFQNRTL RTKSQKKRFE EELNERMIQA IDGINAQKQW LKSEDIQRIS LLFYNKVLEK EYRATALPAF KYYVTCACLI FFCIFIVQIL VLPKTSVLGI SFGAAFLLLA FILFVCFAGQ LLQCSKKASP LLMWLLKSSG IIANRPWPRI SLTIITTAII LMMAVFNMFF LSDSEETIPP TANTTNTSFS ASNNQVAILR AQNLFFLPYF IYSCILGLIS CSVFLRVNYE LKMLIMMVAL VGYNTILLHT HAHVLGDYSQ VLFERPGIWK DLKTMGSVSL SIFFITLLVL GRQNEYYCRL DFLWKNKFKK EREEIETMEN LNRVLLENVL PAHVAEHFLA RSLKNEELYH QSYDCVCVMF ASIPDFKEFY TESDVNKEGL ECLRLLNEII ADFDDLLSKP KFSGVEKIKT IGSTYMAATG LSAVPSQEHS QEPERQYMHI GTMVEFAFAL VGKLDAINKH SFNDFKLRVG INHGPVIAGV IGAQKPQYDI WGNTVNVASR MDSTGVLDKI QVTEETSLVL QTLGYTCTCR GIINVKGKGD LKTYFVNTEM SRSLSQSNVA S
Genular Protein ID: 971448224
Symbol: Q71UM8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8619474
Title: A "double adaptor" method for improved shotgun library construction.
PubMed ID: 8619474
PubMed ID: 9110174
Title: Large-scale concatenation cDNA sequencing.
PubMed ID: 9110174
Sequence Information:
- Length: 367
- Mass: 41622
- Checksum: A4D44988A2679601
- Sequence:
QVAILRAQNL FFLPYFIYSC ILGLISCSVF LRVNYELKML IMMVALVGYN TILLHTHAHV LGDYSQVLFE RPGIWKDLKT MGSVSLSIFF ITLLVLGRQN EYYCRLDFLW KNKFKKEREE IETMENLNRV LLENVLPAHV AEHFLARSLK NEELYHQSYD CVCVMFASIP DFKEFYTESD VNKEGLECLR LLNEIIADFD DLLSKPKFSG VEKIKTIGST YMAATGLSAV PSQEHSQEPE RQYMHIGTMV EFAFALVGKL DAINKHSFND FKLRVGINHG PVIAGVIGAQ KPQYDIWGNT VNVASRMDST GVLDKIQVTE ETSLVLQTLG YTCTCRGIIN VKGKGDLKTY FVNTEMSRSL SQSNVAS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.