ADCY2 | ENSG00000078295 | NCBI 108

Details for: ADCY2

Gene ID: 108

Symbol: ADCY2

Ensembl ID: ENSG00000078295

Description: adenylate cyclase 2

Associated with

Activation of gabab receptors
(R-HSA-991365)
Adenylate cyclase activating pathway
(R-HSA-170660)
Adenylate cyclase inhibitory pathway
(R-HSA-170670)
Adora2b mediated anti-inflammatory cytokines production
(R-HSA-9660821)
Anti-inflammatory response favouring leishmania parasite infection
(R-HSA-9662851)
Aquaporin-mediated transport
(R-HSA-445717)
Ca-dependent events
(R-HSA-111996)
Calmodulin induced events
(R-HSA-111933)
Cam pathway
(R-HSA-111997)
Dag and ip3 signaling
(R-HSA-1489509)
Disease
(R-HSA-1643685)
Fcgr3a-mediated il10 synthesis
(R-HSA-9664323)
G-protein mediated events
(R-HSA-112040)
Gaba b receptor activation
(R-HSA-977444)
Gaba receptor activation
(R-HSA-977443)
G alpha (i) signalling events
(R-HSA-418594)
G alpha (s) signalling events
(R-HSA-418555)
G alpha (z) signalling events
(R-HSA-418597)
Glucagon signaling in metabolic regulation
(R-HSA-163359)
Gpcr downstream signalling
(R-HSA-388396)
Gper1 signaling
(R-HSA-9634597)
Hedgehog 'off' state
(R-HSA-5610787)
Infectious disease
(R-HSA-5663205)
Integration of energy metabolism
(R-HSA-163685)
Intracellular signaling by second messengers
(R-HSA-9006925)
Leishmania infection
(R-HSA-9658195)
Leishmania parasite growth and survival
(R-HSA-9664433)
Metabolism
(R-HSA-1430728)
Neuronal system
(R-HSA-112316)
Neurotransmitter receptors and postsynaptic signal transmission
(R-HSA-112314)
Opioid signalling
(R-HSA-111885)
Parasitic infection pathways
(R-HSA-9824443)
Pka-mediated phosphorylation of creb
(R-HSA-111931)
Pka activation
(R-HSA-163615)
Pka activation in glucagon signalling
(R-HSA-164378)
Plc beta mediated events
(R-HSA-112043)
Signaling by gpcr
(R-HSA-372790)
Signaling by hedgehog
(R-HSA-5358351)
Signal transduction
(R-HSA-162582)
Transmission across chemical synapses
(R-HSA-112315)
Transport of small molecules
(R-HSA-382551)
Vasopressin regulates renal water homeostasis via aquaporins
(R-HSA-432040)
Adenylate cyclase-activating g protein-coupled receptor signaling pathway
(GO:0007189)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Adenylate cyclase activity
(GO:0004016)
Adenylate cyclase binding
(GO:0008179)
Atp binding
(GO:0005524)
Camp-mediated signaling
(GO:0019933)
Camp biosynthetic process
(GO:0006171)
Cellular response to forskolin
(GO:1904322)
Cytoplasm
(GO:0005737)
Dendrite
(GO:0030425)
Magnesium ion binding
(GO:0000287)
Manganese ion binding
(GO:0030145)
Membrane
(GO:0016020)
Membrane raft
(GO:0045121)
Plasma membrane
(GO:0005886)

Other Information

Proteins

Adenylate cyclase type 2
Q71UM8_HUMAN

Genular Protein ID: 2995545697

Symbol: ADCY2_HUMAN

Name: Adenylate cyclase type 2

UniProtKB Accession Codes:

Q08462 B7Z2C1 Q2NKL8 Q9UDB2 Q9UPU2

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 1427768

Title: Different chromosomal localization of two adenylyl cyclase genes expressed in human brain.

PubMed ID: 1427768

DOI: 10.1007/bf00210755

PubMed ID: 8476432

Title: A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line.

PubMed ID: 8476432

DOI: 10.1006/bbrc.1993.1415

PubMed ID: 11549699

Title: Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland.

PubMed ID: 11549699

DOI: 10.1210/jcem.86.9.7837

PubMed ID: 15385642

Title: Raf kinase activation of adenylyl cyclases: isoform-selective regulation.

PubMed ID: 15385642

DOI: 10.1124/mol.66.4.921

PubMed ID: 21228062

Title: Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains.

PubMed ID: 21228062

DOI: 10.1124/jpet.110.177923

Sequence Information:

Length: 1091
Mass: 123603
Checksum: 41FD8BC607C075D1
Sequence:

MWQEAMRRRR YLRDRSEEAA GGGDGLPRSR DWLYESYYCM SQQHPLIVFL LLIVMGSCLA 
LLAVFFALGL EVEDHVAFLI TVPTALAIFF AIFILVCIES VFKKLLRLFS LVIWICLVAM 
GYLFMCFGGT VSPWDQVSFF LFIIFVVYTM LPFNMRDAII ASVLTSSSHT IVLSVCLSAT 
PGGKEHLVWQ ILANVIIFIC GNLAGAYHKH LMELALQQTY QDTCNCIKSR IKLEFEKRQQ 
ERLLLSLLPA HIAMEMKAEI IQRLQGPKAG QMENTNNFHN LYVKRHTNVS ILYADIVGFT 
RLASDCSPGE LVHMLNELFG KFDQIAKENE CMRIKILGDC YYCVSGLPIS LPNHAKNCVK 
MGLDMCEAIK KVRDATGVDI NMRVGVHSGN VLCGVIGLQK WQYDVWSHDV TLANHMEAGG 
VPGRVHISSV TLEHLNGAYK VEEGDGDIRD PYLKQHLVKT YFVINPKGER RSPQHLFRPR 
HTLDGAKMRA SVRMTRYLES WGAAKPFAHL HHRDSMTTEN GKISTTDVPM GQHNFQNRTL 
RTKSQKKRFE EELNERMIQA IDGINAQKQW LKSEDIQRIS LLFYNKVLEK EYRATALPAF 
KYYVTCACLI FFCIFIVQIL VLPKTSVLGI SFGAAFLLLA FILFVCFAGQ LLQCSKKASP 
LLMWLLKSSG IIANRPWPRI SLTIITTAII LMMAVFNMFF LSDSEETIPP TANTTNTSFS 
ASNNQVAILR AQNLFFLPYF IYSCILGLIS CSVFLRVNYE LKMLIMMVAL VGYNTILLHT 
HAHVLGDYSQ VLFERPGIWK DLKTMGSVSL SIFFITLLVL GRQNEYYCRL DFLWKNKFKK 
EREEIETMEN LNRVLLENVL PAHVAEHFLA RSLKNEELYH QSYDCVCVMF ASIPDFKEFY 
TESDVNKEGL ECLRLLNEII ADFDDLLSKP KFSGVEKIKT IGSTYMAATG LSAVPSQEHS 
QEPERQYMHI GTMVEFAFAL VGKLDAINKH SFNDFKLRVG INHGPVIAGV IGAQKPQYDI 
WGNTVNVASR MDSTGVLDKI QVTEETSLVL QTLGYTCTCR GIINVKGKGD LKTYFVNTEM 
SRSLSQSNVA S

Genular Protein ID: 971448224

Symbol: Q71UM8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q71UM8

Database IDs:

Citations:

PubMed ID: 8619474

Title: A "double adaptor" method for improved shotgun library construction.

PubMed ID: 8619474

DOI: 10.1006/abio.1996.0138

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

Sequence Information:

Length: 367
Mass: 41622
Checksum: A4D44988A2679601
Sequence:

QVAILRAQNL FFLPYFIYSC ILGLISCSVF LRVNYELKML IMMVALVGYN TILLHTHAHV 
LGDYSQVLFE RPGIWKDLKT MGSVSLSIFF ITLLVLGRQN EYYCRLDFLW KNKFKKEREE 
IETMENLNRV LLENVLPAHV AEHFLARSLK NEELYHQSYD CVCVMFASIP DFKEFYTESD 
VNKEGLECLR LLNEIIADFD DLLSKPKFSG VEKIKTIGST YMAATGLSAV PSQEHSQEPE 
RQYMHIGTMV EFAFALVGKL DAINKHSFND FKLRVGINHG PVIAGVIGAQ KPQYDIWGNT 
VNVASRMDST GVLDKIQVTE ETSLVLQTLG YTCTCRGIIN VKGKGDLKTY FVNTEMSRSL 
SQSNVAS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: ADCY2

Associated with

Other Information

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The DNA sequence and comparative analysis of human chromosome 5. PubMed ID: 15372022

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. PubMed ID: 10470851

Different chromosomal localization of two adenylyl cyclase genes expressed in human brain. PubMed ID: 1427768

A novel adenylyl cyclase sequence cloned from the human erythroleukemia cell line. PubMed ID: 8476432

Expression and regulation of adenylyl cyclase isoforms in the human adrenal gland. PubMed ID: 11549699

Raf kinase activation of adenylyl cyclases: isoform-selective regulation. PubMed ID: 15385642

Human bronchial smooth muscle cells express adenylyl cyclase isoforms 2, 4, and 6 in distinct membrane microdomains. PubMed ID: 21228062

A "double adaptor" method for improved shotgun library construction. PubMed ID: 8619474

Large-scale concatenation cDNA sequencing. PubMed ID: 9110174